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Cheap flights from South Carolina to Manchester from £281

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
24 May — 31 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 24 April 2026.

Mon 9/1106:00
GSP
-
MAN
2 stops22h 00m
United Airlines
Wed 11/1106:10
MAN
-
GSP
2 stops15h 50m
United Airlines
Deal found 18/4£599
Mon 16/1113:00
MYR
-
MAN
2 stops16h 20m
United Airlines
Wed 18/1106:10
MAN
-
MYR
2 stops37h 23m
United Airlines
Deal found 18/4£603
Tue 15/918:40
CLT
-
MAN
2 stops18h 15m
SWISS
Tue 22/909:00
MAN
-
CLT
2 stops17h 30m
SWISS
Deal found 19/4£638
Tue 25/815:40
CLT
-
MAN
1 stop9h 50m
Air Canada
Fri 18/909:00
MAN
-
CLT
2 stops41h 30m
Air Canada
Deal found 22/4£641
Mon 24/819:49
CLT
-
MAN
2 stops29h 41m
Air Canada
Fri 18/909:00
MAN
-
CLT
2 stops33h 50m
Air Canada
Deal found 22/4£644
Tue 15/917:55
CLT
-
MAN
1 stop14h 10m
American Airlines
Tue 22/912:20
MAN
-
CLT
1 stop11h 40m
American Airlines
Deal found 19/4£645
Mon 24/818:59
CLT
-
MAN
1 stop32h 21m
Delta
Fri 18/914:55
MAN
-
CLT
1 stop12h 28m
Delta
Deal found 22/4£649
Tue 15/914:30
CLT
-
MAN
2 stops17h 35m
British Airways
Thu 1/1020:00
MAN
-
CLT
2 stops24h 05m
British Airways
Deal found 22/4£650
Tue 25/815:40
CLT
-
MAN
1 stop9h 50m
United Airlines
Fri 18/909:00
MAN
-
CLT
1 stop10h 57m
United Airlines
Deal found 22/4£651
Tue 15/920:20
CLT
-
MAN
1 stop11h 45m
American Airlines
Thu 1/1007:45
MAN
-
CLT
2 stops14h 50m
American Airlines
Deal found 22/4£652
Wed 26/814:10
CLT
-
MAN
2 stops14h 55m
Delta
Fri 18/913:00
MAN
-
CLT
1 stop13h 38m
Delta
Deal found 22/4£653
Tue 15/918:59
CLT
-
MAN
2 stops14h 01m
Multiple Airlines
Tue 22/915:00
MAN
-
CLT
1 stop12h 23m
Multiple Airlines
Deal found 19/4£654

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 24 April 2026.

Round-trip from

£638

One-way from

£281

Popular in

July

Cheapest in

November

Average price

£532
SWISS
  • SWISS
  • 15/9-22/9
  • 4 total stops
  • 35h 45m total
  • South Carolina to Manchester
Search Deals
12/7
  • 12/7
  • 3 total stops
  • 53h 56m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 24% potential increase in price (£181 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£26 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 24 April 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight
Fastest return journey

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 15/9

18:59-14:00

2 stops14h 01m

Manchester

Tue 22/9

15:00-22:23

1 stop12h 23m

£654

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 9/9

15:14-17:35

2 stops21h 21m

Manchester

Mon 14/9

06:05-21:32

2 stops20h 27m

£742

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 7/5

09:45-08:20

1 stop17h 35m

Manchester

Tue 12/5

15:00-22:47

1 stop12h 47m

£767

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 7/5

09:41-08:20

2 stops17h 39m

Manchester

Tue 12/5

15:00-22:47

1 stop12h 47m

£767

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Tue 12/5

10:33-10:25

2 stops18h 52m

Manchester

Wed 27/5

06:05-19:04

2 stops17h 59m

£793

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Sun 10/5

06:36-10:25

2 stops22h 49m

Manchester

Thu 28/5

06:05-17:00

2 stops15h 55m

£793

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 9/9

07:25-08:15

1 stop19h 50m

Manchester

Mon 14/9

14:55-10:35

1 stop24h 40m

£798

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 9/9

19:15-06:30

2 stops30h 15m

Manchester

Mon 14/9

06:05-23:22

3 stops22h 17m

£798

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sat 9/5

19:43-10:25

2 stops33h 42m

Manchester

Thu 28/5

06:05-23:59

2 stops22h 54m

£830

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 21/7

06:15-06:30

2 stops19h 15m

Manchester

Sun 26/7

09:00-14:57

1 stop10h 57m

£831

Flights are sorted by cheapest return flights first.

Deals found on 20/4

Showing 1-10 of 47 resultsSorted by cheapest first
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5

Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £438). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,001). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from South Carolina to Manchester?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 17h 35m. United Airlines provides one of the quickest options available for as low as £767. Airlines will cover a distance of 3870 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Manchester one-way?

    The cheapet airlines for a one-way flight from South Carolina to Manchester are Air France (£179), TUI Airways (£248), and KLM (£288).

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Myrtle Beach Intl - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £438). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,001). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

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Otley
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Lancaster
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Preston
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Bolton
Wilmslow
Macclesfield

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Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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