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Cheap flights from Manchester to Des Moines from £372

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 29/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — DSM
22 Mar — 29 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Des Moines

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Des Moines
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 20 February 2026.

Mon 1/609:35
MAN
-
DSM
2 stops18h 57m
Scandinavian Airlines
Mon 15/614:15
DSM
-
MAN
2 stops36h 40m
Scandinavian Airlines
Deal found 19/2£733
Thu 5/309:10
MAN
-
DSM
2 stops18h 30m
Multiple Airlines
Tue 10/314:04
DSM
-
MAN
2 stops19h 46m
Multiple Airlines
Deal found 16/2£908
Tue 2/605:55
MAN
-
DSM
2 stops38h 25m
Lufthansa
Tue 16/606:00
DSM
-
MAN
2 stops18h 30m
Lufthansa
Deal found 17/2£960
Tue 2/614:25
MAN
-
DSM
2 stops24h 01m
Aer Lingus
Tue 16/613:46
DSM
-
MAN
2 stops35h 54m
Aer Lingus
Deal found 18/2£966
Thu 5/313:30
MAN
-
DSM
1 stop14h 58m
Delta
Tue 10/305:35
DSM
-
MAN
2 stops23h 35m
Delta
Deal found 16/2£971
Sat 6/606:05
MAN
-
DSM
2 stops15h 43m
Lufthansa
Thu 11/605:00
DSM
-
MAN
2 stops19h 30m
Lufthansa
Deal found 17/2£999

Find flight deals from Manchester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 20 February 2026.

Round-trip from

£733

One-way from

£372

Popular in

July

Cheapest in

November

Average price

£910
Scandinavian Airlines
  • Scandinavian Airlines
  • 1/6-15/6
  • 4 total stops
  • 55h 37m total
  • Manchester to Des Moines
Search Deals
29/5
  • 29/5
  • 3 total stops
  • 56h 38m total
  • Manchester to Des Moines
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (£92 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£17 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 20 February 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Manchester

Fly to

Des Moines

Route

Depart

Return

Price

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

09:35-22:32

2 stops18h 57m

Des Moines

Mon 15/6

11:04-08:55

2 stops39h 51m

£792

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Thu 5/3

09:10-21:40

2 stops18h 30m

Des Moines

Tue 10/3

14:04-14:50

2 stops19h 46m

£908

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

05:55-14:20

2 stops38h 25m

Des Moines

Tue 16/6

06:00-06:30

2 stops18h 30m

£960

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

14:25-08:26

2 stops24h 01m

Des Moines

Tue 16/6

13:46-07:40

2 stops35h 54m

£966

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Thu 5/3

13:30-22:28

1 stop14h 58m

Des Moines

Tue 10/3

05:35-10:10

2 stops23h 35m

£971

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Sat 6/6

06:05-15:48

2 stops15h 43m

Des Moines

Thu 11/6

05:00-06:30

2 stops19h 30m

£999

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Sat 6/6

08:10-17:59

2 stops15h 49m

Des Moines

Thu 11/6

05:15-07:40

2 stops20h 25m

£1,006

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Sat 6/6

08:10-19:28

2 stops17h 18m

Des Moines

Fri 12/6

05:15-08:40

2 stops21h 25m

£1,025

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Thu 5/3

06:10-21:40

3 stops21h 30m

Des Moines

Tue 10/3

08:00-10:20

3 stops21h 20m

£1,052

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

13:00-17:53

1 stop34h 53m

Des Moines

Tue 16/6

17:25-14:00

2 stops14h 35m

£1,061

Flights are sorted by cheapest return flights first.

Deals found on 17/2

Showing 1-10 of 15 results
1
2

Best time to book a flight from Manchester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Des Moines

What is the cheapest month to book a flight from Manchester to Des Moines?

Currently, March is the cheapest month in which you can book a flight from Manchester to Des Moines (average of £595). Flying from Manchester to Des Moines in July is currently the most expensive (average of £1,005). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated 20 February 2026.
Get a feel of what it's like to fly with KLM, Virgin Atlantic, andAer Lingus from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,458 reviews
Check prices

Crew

8.4

Entertainment

7.1

Comfort

7.6

Food

7.3

Overall

7.7

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.7
Good
1,458 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Crew

8.4

Entertainment

7.1

Comfort

7.6

Food

7.3

Overall

7.7

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Virgin Atlantic
7.5
Good
679 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Crew

8.4

Entertainment

7.1

Comfort

7.6

Food

7.3

Overall

7.7

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Aer Lingus
7.2
Good
1,455 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Crew

8.4

Entertainment

7.1

Comfort

7.6

Food

7.3

Overall

7.7

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6.7
Okay
7,753 reviews
KLM
7.7
Good
1,458 reviews
Check prices

Crew

8.4

Entertainment

7.1

Comfort

7.6

Food

7.3

Overall

7.7

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester to Des Moines?

    Airlines like Scandinavian Airlines, Lufthansa, and Aer Lingus fly from Manchester to Des Moines in about 18h 57m. The time it takes to get you to your destination can typically vary by up to 19h 28m. There are 4045 mi between Manchester and Des Moines. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Manchester to Des Moines round-trip?

    Currently priced at £665, British Airways will fly you from Manchester to Des Moines and back. In addition to British Airways, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Virgin Atlantic and KLM - these airlines can fly you to your destination from £773 and £812, respectively. You may be able to fly from Manchester to Des Moines for 27% less than the average price by searching for these airlines.

  • Can I find deals for flights from Manchester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Manchester to Des Moines flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Des Moines.

  • Can I find deals for business class flights from Manchester to Des Moines?

    Yes. Cheapflights offers flight deals from Manchester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Des Moines?

    Currently, March is the cheapest month in which you can book a flight from Manchester to Des Moines (average of £595). Flying from Manchester to Des Moines in July is currently the most expensive (average of £1,005). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Manchester to Des Moines

Discover the top 4 airlines that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 20 February 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£665Average£909FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£773Average£910FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£812Average£899FlexibilityNo cancel feeOn-time75%
Search KLM flights
Aer LingusCheapest£923Average£997FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Des Moines?

When you search for this flight from Manchester to Des Moines, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Des Moines?

Millions of users choose and trust Cheapflights to book the best flight deals from Manchester to Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Manchester to Des Moines with no change fees?

Certainly. Search results for flights to Des Moines from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Manchester to Des Moines become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Des Moines from Manchester today and book when prices fit your budget.

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