Cheap flights from Manchester to Des Moines from £365

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — DSM
8 May — 15 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Des Moines

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Des Moines
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 8 April 2026.

Tue 2/620:55
MAN
-
DSM
2 stops27h 41m
Multiple Airlines
Tue 16/613:48
DSM
-
MAN
2 stops18h 07m
Multiple Airlines
Deal found 4/4£1,002
Mon 1/620:55
MAN
-
DSM
2 stops28h 37m
Multiple Airlines
Mon 15/620:02
DSM
-
MAN
2 stops29h 38m
Multiple Airlines
Deal found 3/4£1,017
Mon 1/606:00
MAN
-
DSM
2 stops19h 25m
Lufthansa
Mon 15/620:15
DSM
-
MAN
2 stops32h 10m
Lufthansa
Deal found 6/4£1,030
Mon 29/608:00
MAN
-
DSM
2 stops17h 32m
Multiple Airlines
Sat 11/718:51
DSM
-
MAN
2 stops53h 39m
Multiple Airlines
Deal found 4/4£1,041

Find flight deals from Manchester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MAN) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 8 April 2026.

Round-trip from

£1,002

One-way from

£365

Popular in

July

Cheapest in

October

Average price

£998
Aer Lingus
  • Aer Lingus
  • 2/6-16/6
  • 4 total stops
  • 45h 48m total
  • Manchester to Des Moines
6/5
  • 6/5
  • 3 total stops
  • 37h 11m total
  • Manchester to Des Moines
Highest demand for flights based on searches. 9% potential increase in price (£69 potential increase over avg. return price).
Cheapest flight prices on average. 2% potential price decrease (£17 potential savings vs. average return price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 8 April 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

20:55-00:08

2 stops33h 13m

Des Moines

Tue 16/6

13:48-13:55

2 stops18h 07m

£1,010

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

06:00-19:25

2 stops19h 25m

Des Moines

Mon 15/6

20:15-10:25

2 stops32h 10m

£1,030

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

05:55-22:35

2 stops22h 40m

Des Moines

Tue 16/6

05:00-10:25

2 stops23h 25m

£1,030

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Tue 2/6

13:00-11:08

1 stop28h 08m

Des Moines

Tue 16/6

14:45-14:00

2 stops17h 15m

£1,146
Fastest return journey

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Mon 1/6

05:55-20:36

2 stops20h 41m

Des Moines

Mon 15/6

05:25-08:50

1 stop21h 25m

£1,196
Cheapest one-way

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Wed 6/5

06:35-13:46

3 stops37h 11m

£365
Fastest single journey

ManchesterDes Moines

MAN - DSM

MANDSM

Manchester

Wed 6/5

10:40-22:34

1 stop17h 54m

£802

Flights are sorted by cheapest return flights first.

Deals found on 4/4

Sorted by cheapest first

Best time to book a flight from Manchester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Des Moines

What is the cheapest month to book a flight from Manchester to Des Moines?

Currently, October is the cheapest month in which you can book a flight from Manchester to Des Moines (average of £427). Flying from Manchester to Des Moines in July is currently the most expensive (average of £1,021). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated 8 April 2026.
Get a feel of what it's like to fly with Delta,Virgin Atlantic, andAer Lingus from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.2

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Manchester to Des Moines?

    Airlines like Lufthansa and Delta fly from Manchester to Des Moines in about 19h 25m. The time it takes to get you to your destination can typically vary by up to 8h 43m. There are 4045 mi between Manchester and Des Moines. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Manchester to Des Moines round-trip?

    Currently priced at £789, British Airways will fly you from Manchester to Des Moines and back. In addition to British Airways, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Virgin Atlantic and Aer Lingus - these airlines can fly you to your destination from £793 and £939, respectively. You may be able to fly from Manchester to Des Moines for 15% less than the average price by searching for these airlines.

  • Can I find deals for flights from Manchester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Manchester to Des Moines flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Des Moines.

  • Can I find deals for business class flights from Manchester to Des Moines?

    Yes. Cheapflights offers flight deals from Manchester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Des Moines?

    Currently, October is the cheapest month in which you can book a flight from Manchester to Des Moines (average of £427). Flying from Manchester to Des Moines in July is currently the most expensive (average of £1,021). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Manchester to Des Moines

Discover the top 4 airlines that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 8 April 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£789Average£992FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£793Average£934FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
Aer LingusCheapest£939Average£1,015FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights
DeltaCheapest£948Average£1,096FlexibilityNo cancel feeOn-timeN/A
Search Delta flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Des Moines?

When you search for this flight from Manchester to Des Moines, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Des Moines?

Millions of users choose and trust Cheapflights to book the best flight deals from Manchester to Des Moines for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Manchester to Des Moines with no change fees?

Certainly. Search results for flights to Des Moines from Manchester shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Manchester to Des Moines become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Des Moines from Manchester today and book when prices fit your budget.

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