Find flights
When to book
FAQs

Cheap flights from Frankfurt am Main Airport to Panama City from £455

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/9. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — PTY
12 Sep — 19 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Frankfurt to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Frankfurt to Panama City
Explore the most affordable flight options available from Frankfurt to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 August 2026.

Tue 27/1010:45 -
1 stop15h 00m
Tue 10/1121:30 -
1 stop14h 25m
Deal found 13/8£575
Wed 28/1010:45 -
1 stop15h 00m
Tue 10/1121:30 -
1 stop14h 25m
Deal found 11/8£576
Tue 27/1010:45 -
1 stop15h 00m
Sun 8/1121:30 -
1 stop30h 15m
Deal found 13/8£581
Sat 31/1018:55 -
1 stop30h 50m
Tue 10/1121:30 -
1 stop14h 25m
Deal found 12/8£583
Thu 29/1018:55 -
1 stop30h 50m
Tue 10/1121:30 -
1 stop14h 25m
Deal found 11/8£584
Thu 29/1018:55 -
1 stop30h 50m
Thu 12/1121:30 -
1 stop14h 25m
Deal found 10/8£585
Tue 27/1010:45 -
1 stop15h 00m
Sat 7/1121:30 -
1 stop30h 15m
Deal found 13/8£586
Thu 5/1118:55 -
1 stop30h 50m
Thu 12/1121:30 -
1 stop14h 25m
Deal found 13/8£589
Mon 26/1018:55 -
1 stop30h 50m
Sun 8/1121:30 -
1 stop30h 15m
Deal found 13/8£589
Thu 29/1018:55 -
1 stop30h 50m
Sun 8/1121:30 -
1 stop30h 15m
Deal found 11/8£590
Tue 20/1019:10 -
1 stop30h 30m
Thu 29/1021:30 -
1 stop30h 15m
Deal found 13/8£594

Find flight deals from Frankfurt to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 13 August 2026.

Round-trip from

£575

One-way from

£455

Popular in

June

Cheapest in

September

Average price

£674
Air Europa
  • Air Europa
  • 27/10-12/11
  • 2 total stops
  • 29h 25m total
  • Frankfurt am Main to Panama City
Search Deals
15/9
  • 15/9
  • 2 total stops
  • 20h 15m total
  • Frankfurt am Main to Panama City
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (£24 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (£6 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Frankfurt to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 August 2026.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Thu 3/9

06:35-19:31

2 stops19h 56m

Panama City Tocumen Intl

Thu 10/9

09:45-11:15

2 stops18h 30m

£614

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Mon 14/9

07:45-19:31

2 stops18h 46m

Panama City Tocumen Intl

Mon 28/9

10:00-12:05

2 stops19h 05m

£618

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Sun 30/8

08:20-19:31

2 stops18h 11m

Panama City Tocumen Intl

Tue 8/9

10:00-06:30

2 stops37h 30m

£619

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Sat 12/9

11:10-19:31

1 stop15h 21m

Panama City Tocumen Intl

Sat 19/9

09:45-09:10

1 stop16h 25m

£619
Fastest return journey

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Mon 7/9

11:10-19:31

1 stop15h 21m

Panama City Tocumen Intl

Mon 14/9

09:45-07:35

1 stop14h 50m

£620

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Sun 1/11

13:50-14:45

1 stop30h 55m

Panama City Tocumen Intl

Sat 14/11

08:55-11:40

1 stop20h 45m

£620

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Mon 28/12

13:50-17:12

1 stop33h 22m

Panama City Tocumen Intl

Fri 15/1

11:35-06:35

2 stops37h 00m

£620

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Sat 3/10

17:10-19:31

2 stops33h 21m

Panama City Tocumen Intl

Sat 10/10

15:30-09:20

2 stops34h 50m

£620

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Sun 8/11

13:50-14:45

1 stop30h 55m

Panama City Tocumen Intl

Sun 6/12

08:55-11:40

1 stop20h 45m

£620
Cheapest one-way

Frankfurt am MainPanama City

FRA Frankfurt am Main - PTY Panama City Tocumen Intl

FRAPTY

Frankfurt am Main

Tue 8/9

20:00-09:15

2 stops20h 15m

£456

Flights are sorted by cheapest return flights first.

Deals found on 9/8

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Frankfurt to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Frankfurt with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Panama City

How far ahead should I book a flight from Frankfurt am Main Airport to Panama City?

To ensure you get the cheapest price possible for a flight from Frankfurt am Main Airport to Panama City, you should look to book at least 11 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

Currently, September is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £512). Flying from Frankfurt am Main Airport to Panama City in June is currently the most expensive (average of £706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Frankfurt am Main Airport to Panama City?

Airfare is below average for this route at the moment.

Frankfurt am Main Airport to Panama City flights typically cost between £606 and £752 in October.
The cheapest return price found within the last 5 days was £575 on Air Europa (27 Oct–10 Nov).

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Frankfurt am Main?

    For a flight from Frankfurt am Main to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from Frankfurt am Main per day. 0 airlines have flights to Panama City Tocumen Intl from Frankfurt am Main on a regular basis.

  • How long is the flight from Frankfurt am Main Airport to Panama City?

    Departing from Frankfurt am Main Airport to Panama City will take you 19h 56m. Airlines will cover a distance of 5644 mi.

  • Can I find deals for flights from Frankfurt to Panama City that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Panama City.

  • Can I find deals for business class flights from Frankfurt to Panama City?

    Yes. Cheapflights offers flight deals from Frankfurt to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

    Currently, September is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £512). Flying from Frankfurt am Main Airport to Panama City in June is currently the most expensive (average of £706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Frankfurt to Panama City?

Deals for Frankfurt to Panama City flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Frankfurt to Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Frankfurt to Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Frankfurt to Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Frankfurt to Panama City with no change fees.

Can Cheapflights notify me if prices for flights from Frankfurt to Panama City become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.