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Cheap flights from South Carolina to Manchester from £168

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
27 Feb — 6 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 January 2026.

Mon 26/1019:50
CLT
-
MAN
1 stop17h 05m
Lufthansa
Tue 3/1106:25
MAN
-
CLT
1 stop15h 30m
Lufthansa
Deal found 25/1£446
Tue 5/518:40
CLT
-
MAN
1 stop17h 25m
Lufthansa
Thu 14/507:00
MAN
-
CLT
1 stop14h 45m
Lufthansa
Deal found 26/1£453
Tue 5/516:34
CLT
-
MAN
2 stops15h 31m
British Airways
Thu 14/520:00
MAN
-
CLT
2 stops24h 05m
British Airways
Deal found 25/1£454
Wed 4/314:01
SAV
-
MAN
1 stop15h 29m
Delta
Tue 10/313:00
MAN
-
SAV
1 stop13h 03m
Delta
Deal found 27/1£454
Wed 11/306:00
CHS
-
MAN
1 stop20h 40m
Virgin Atlantic
Wed 18/313:30
MAN
-
CHS
1 stop12h 24m
Virgin Atlantic
Deal found 26/1£454
Wed 11/316:57
SAV
-
MAN
1 stop13h 33m
Delta
Wed 18/313:30
MAN
-
SAV
1 stop14h 29m
Delta
Deal found 27/1£456
Wed 4/319:23
SAV
-
MAN
2 stops15h 57m
American Airlines
Tue 10/308:05
MAN
-
SAV
2 stops13h 51m
American Airlines
Deal found 25/1£458
Wed 11/314:48
CHS
-
MAN
2 stops20h 02m
Lufthansa
Wed 18/306:00
MAN
-
CHS
2 stops18h 57m
Lufthansa
Deal found 26/1£459
Mon 26/1018:00
CLT
-
MAN
2 stops17h 10m
British Airways
Tue 3/1112:35
MAN
-
CLT
2 stops14h 20m
British Airways
Deal found 25/1£461
Wed 4/315:41
SAV
-
MAN
2 stops13h 29m
KLM
Tue 10/313:30
MAN
-
SAV
1 stop14h 29m
KLM
Deal found 26/1£462
Tue 18/819:47
CLT
-
MAN
2 stops22h 28m
Lufthansa
Tue 1/910:35
MAN
-
CLT
2 stops17h 54m
Lufthansa
Deal found 26/1£463
Wed 11/312:44
CHS
-
MAN
2 stops17h 26m
Delta
Wed 18/309:05
MAN
-
CHS
2 stops16h 19m
Delta
Deal found 25/1£465

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 28 January 2026.

Round-trip from

£452

One-way from

£168

Popular in

August

Cheapest in

January

Average price

£357
Delta
  • Delta
  • 26/2-11/3
  • 2 total stops
  • 38h 14m total
  • South Carolina to Manchester
Search Deals
24/3
  • 24/3
  • 3 total stops
  • 47h 27m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 34% potential increase in price (£302 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 17% potential price decrease (£86 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 January 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

South Carolina

Fly to

Manchester

Route

Depart

Return

Price

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 4/3

14:01-10:30

1 stop15h 29m

Manchester

Tue 10/3

13:00-22:03

1 stop13h 03m

£454

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 11/3

06:00-06:40

1 stop20h 40m

Manchester

Wed 18/3

13:30-21:54

1 stop12h 24m

£454

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

16:34-13:10

2 stops15h 36m

Manchester

Thu 14/5

20:00-15:05

2 stops24h 05m

£456

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 4/3

11:59-10:55

2 stops17h 56m

Manchester

Tue 10/3

08:05-17:56

2 stops13h 51m

£458

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 11/3

14:48-14:50

2 stops20h 02m

Manchester

Wed 18/3

06:00-20:57

2 stops18h 57m

£459

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 4/3

15:41-10:10

2 stops13h 29m

Manchester

Tue 10/3

13:30-23:59

1 stop14h 29m

£462

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 11/3

11:43-10:10

2 stops18h 27m

Manchester

Wed 18/3

13:30-23:59

1 stop14h 29m

£464

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 11/3

12:44-10:10

2 stops17h 26m

Manchester

Wed 18/3

09:05-21:24

2 stops16h 19m

£465

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 11/3

19:47-10:20

2 stops34h 33m

Manchester

Wed 18/3

06:10-19:00

2 stops16h 50m

£467

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 11/3

11:28-10:20

2 stops18h 52m

Manchester

Wed 18/3

06:10-14:40

2 stops36h 30m

£469

Flights are sorted by cheapest return flights first.

Deals found on 27/1

Showing 1-10 of 44 results
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £357). Flying from South Carolina to Manchester in June is currently the most expensive (average of £655). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 15h 29m. Delta provides one of the quickest options available for as low as £454. Airlines will cover a distance of 4033 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Charleston - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £357). Flying from South Carolina to Manchester in June is currently the most expensive (average of £655). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Bradford
Lincoln
Derby
Harrogate
Stoke-on-Trent
Otley
Southport
Telford
Lancaster
Wakefield
Bolton
Preston
Salford
Huddersfield
Stockport
Rochdale
Blackburn
Skipton

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Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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