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Cheap flights from South Carolina to Manchester from £213

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
4 Dec — 11 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 4 November 2025.

Round-trip from

£436

One-way from

£213

Popular in

August

Cheapest in

October

Average price

£517
Virgin Atlantic
  • Virgin Atlantic
  • 3/12-10/12
  • 2 total stops
  • 27h 50m total
  • South Carolina to Manchester
Search Deals
2/2
  • 2/2
  • 3 total stops
  • 35h 24m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 33% potential increase in price (£319 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 16% potential price decrease (£93 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 4 November 2025.

Wed 3/1217:00CHS - MAN
1 stop12h 30mVirgin Atlantic
Wed 10/1213:30MAN - CHS
1 stop15h 20mVirgin Atlantic
Deal found 3/11£436
Wed 3/1206:00CHS - MAN
1 stop19h 40mMultiple Airlines
Wed 10/1209:05MAN - CHS
2 stops16h 56mMultiple Airlines
Deal found 3/11£464
Wed 3/1217:38CHS - MAN
2 stops17h 42mAmerican Airlines
Wed 10/1208:05MAN - CHS
2 stops20h 13mAmerican Airlines
Deal found 3/11£468
Fri 5/1218:50CLT - MAN
2 stops20h 35mMultiple Airlines
Tue 9/1219:50MAN - CLT
3 stops30h 07mMultiple Airlines
Deal found 2/11£470
Tue 9/1214:52GSP - MAN
2 stops16h 28mUnited Airlines
Tue 16/1206:10MAN - GSP
2 stops18h 00mUnited Airlines
Deal found 2/11£486
Wed 3/1223:00CLT - MAN
1 stop12h 20mBritish Airways
Wed 10/1208:55MAN - CLT
1 stop12h 05mBritish Airways
Deal found 3/11£503
Mon 3/1106:00CLT - MAN
2 stops31h 35mScandinavian Airlines
Fri 7/1119:15MAN - CLT
2 stops32h 22mScandinavian Airlines
Deal found 2/11£505
Mon 17/1115:47CHS - MAN
2 stops21h 48mScandinavian Airlines
Thu 20/1119:15MAN - CHS
2 stops32h 35mScandinavian Airlines
Deal found 3/11£505
Wed 3/1223:00CLT - MAN
1 stop14h 45mAmerican Airlines
Wed 10/1208:05MAN - CLT
2 stops16h 33mAmerican Airlines
Deal found 3/11£512
Sun 30/1120:23SAV - MAN
2 stops16h 42mAmerican Airlines
Sun 7/1208:05MAN - SAV
2 stops14h 44mAmerican Airlines
Deal found 2/11£526
Thu 13/1114:15CLT - MAN
2 stops23h 20mScandinavian Airlines
Sun 16/1119:15MAN - CLT
2 stops31h 40mScandinavian Airlines
Deal found 3/11£527
Wed 3/1205:35CLT - MAN
2 stops24h 10mMultiple Airlines
Wed 10/1211:55MAN - CLT
3 stops31h 08mMultiple Airlines
Deal found 3/11£532

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 November 2025.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

South Carolina

Fly to

Manchester

Route

Depart

Return

Price

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 3/12

17:00-10:30

1 stop12h 30m

Manchester

Wed 10/12

13:30-23:50

1 stop15h 20m

£436

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 3/12

06:00-06:40

1 stop19h 40m

Manchester

Wed 10/12

09:05-21:01

2 stops16h 56m

£464

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Wed 3/12

17:38-16:20

2 stops17h 42m

Manchester

Wed 10/12

08:05-23:18

2 stops20h 13m

£468

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Tue 9/12

14:52-12:20

2 stops16h 28m

Manchester

Tue 16/12

06:10-19:10

2 stops18h 00m

£486

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Tue 9/12

14:52-12:20

2 stops16h 28m

Manchester

Tue 16/12

06:10-19:10

2 stops18h 00m

£486

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 26/2

18:30-14:20

1 stop14h 50m

Manchester

Wed 4/3

06:10-14:20

1 stop13h 10m

£504

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 1/3

06:00-18:35

2 stops31h 35m

Manchester

Thu 5/3

19:15-22:24

2 stops32h 09m

£505

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 26/2

11:49-09:30

2 stops16h 41m

Manchester

Wed 4/3

19:15-22:42

2 stops32h 27m

£505

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Mon 17/11

15:47-18:35

2 stops21h 48m

Manchester

Thu 20/11

19:15-22:50

2 stops32h 35m

£505

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 3/12

23:00-18:45

1 stop14h 45m

Manchester

Wed 10/12

08:05-19:38

2 stops16h 33m

£512

Flights are sorted by cheapest return flights first.

Deals found on 3/11

Showing 1-10 of 42 results
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £374). Flying from South Carolina to Manchester in June is currently the most expensive (average of £836). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MAN?

Find hourly flight availability from South Carolina to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 4 November 2025.

It’s typically best to fly out from South Carolina to Manchester in the evening. Doing so could potentially save you 33% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 12h 30m. Virgin Atlantic provides one of the quickest options available for as low as £436. Airlines will cover a distance of 3948 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Charleston - Manchester or Greenville - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £374). Flying from South Carolina to Manchester in June is currently the most expensive (average of £836). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
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Southport
Blackburn
Stoke-on-Trent
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Telford
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Warrington
Huddersfield

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Alternative routes for South Carolina to Manchester

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Top airline flying from South Carolina to Manchester

Discover the top airline that operate flights from South Carolina to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 November 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£489Average£960FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from South Carolina to Manchester become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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