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Cheap flights from South Carolina to Manchester from £207

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
18 Dec — 25 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 18 November 2025.

Round-trip from

£464

One-way from

£207

Popular in

August

Cheapest in

October

Average price

£726
American Airlines
  • American Airlines
  • 3/3-17/3
  • 2 total stops
  • 29h 20m total
  • South Carolina to Manchester
Search Deals
5/12
  • 5/12
  • 2 total stops
  • 16h 53m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 30% potential increase in price (£296 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 15% potential price decrease (£91 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 November 2025.

Tue 2/1209:30CLT - MAN
2 stops24h 20mMultiple Airlines
Tue 9/1209:10MAN - CLT
2 stops16h 47mMultiple Airlines
Deal found 17/11£575
Mon 15/1211:38CLT - MAN
2 stops15h 17mDelta
Wed 24/1213:30MAN - CLT
1 stop15h 16mDelta
Deal found 16/11£577
Mon 15/1211:38CLT - MAN
2 stops15h 17mDelta
Thu 25/1213:30MAN - CLT
1 stop29h 16mDelta
Deal found 16/11£581
Wed 31/1218:00CLT - MAN
2 stops14h 55mBritish Airways
Wed 7/118:30MAN - CLT
1 stop24h 45mBritish Airways
Deal found 16/11£586
Wed 31/1223:00CLT - MAN
1 stop14h 45mAmerican Airlines
Wed 7/108:55MAN - CLT
1 stop15h 10mAmerican Airlines
Deal found 16/11£604
Wed 3/1218:56MYR - MAN
1 stop10h 34mVirgin Atlantic
Sun 7/1209:05MAN - MYR
1 stop19h 38mVirgin Atlantic
Deal found 16/11£617
Wed 31/1211:02CLT - MAN
2 stops16h 38mUnited Airlines
Wed 7/113:00MAN - CLT
2 stops34h 59mUnited Airlines
Deal found 15/11£618
Wed 3/1214:40MYR - MAN
2 stops14h 30mDelta
Sun 7/1210:25MAN - MYR
2 stops18h 18mDelta
Deal found 16/11£624
Sun 14/1222:50CLT - MAN
1 stop11h 45mBritish Airways
Sun 21/1207:55MAN - CLT
2 stops18h 29mBritish Airways
Deal found 16/11£628
Fri 12/1216:05MYR - MAN
2 stops19h 30mBritish Airways
Tue 16/1206:15MAN - MYR
2 stops17h 06mBritish Airways
Deal found 17/11£631
Wed 17/1208:19CLT - MAN
2 stops18h 36mDelta
Wed 24/1213:30MAN - CLT
1 stop15h 16mDelta
Deal found 17/11£641
Wed 31/1214:34MYR - MAN
2 stops18h 21mAmerican Airlines
Wed 7/107:50MAN - MYR
2 stops21h 07mAmerican Airlines
Deal found 16/11£648

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 November 2025.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

South Carolina

Fly to

Manchester

Route

Depart

Return

Price

Myrtle BeachManchester

MYR - MAN

MYRMAN

Myrtle Beach Intl

Sun 18/1

10:33-10:10

2 stops18h 37m

Manchester

Sat 31/1

13:30-23:43

1 stop15h 13m

£474

Myrtle BeachManchester

MYR - MAN

MYRMAN

Myrtle Beach Intl

Sun 18/1

10:33-08:40

1 stop17h 07m

Manchester

Sat 31/1

13:30-09:46

1 stop25h 16m

£475

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 5/5

18:59-08:24

1 stop32h 25m

Manchester

Wed 13/5

14:50-18:18

1 stop32h 28m

£491

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 5/5

10:00-08:24

1 stop17h 24m

Manchester

Tue 12/5

11:00-08:38

1 stop26h 38m

£491

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 5/5

18:59-08:24

1 stop32h 25m

Manchester

Fri 15/5

11:00-19:21

1 stop13h 21m

£491

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

18:59-16:50

2 stops16h 51m

Manchester

Fri 15/5

11:00-11:06

1 stop29h 06m

£495

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

18:59-16:50

2 stops16h 51m

Manchester

Tue 12/5

14:50-10:07

1 stop24h 17m

£495

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

18:59-16:50

2 stops16h 51m

Manchester

Thu 14/5

15:50-11:06

2 stops24h 16m

£498

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

18:59-16:50

2 stops16h 51m

Manchester

Wed 13/5

06:00-21:05

2 stops20h 05m

£501

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 26/2

18:30-14:20

1 stop14h 50m

Manchester

Wed 4/3

06:10-14:20

1 stop13h 10m

£502

Flights are sorted by cheapest return flights first.

Deals found on 15/11

Showing 1-10 of 45 results
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £373). Flying from South Carolina to Manchester in June is currently the most expensive (average of £834). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MAN?

Find hourly flight availability from South Carolina to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 18 November 2025.

It’s typically best to fly out from South Carolina to Manchester in the evening. Doing so could potentially save you 33% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 17h 07m. Air France provides one of the quickest options available for as low as £475. Airlines will cover a distance of 3864 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Manchester one-way?

    The cheapet airlines for a one-way flight from South Carolina to Manchester are United Airlines (£335), Aer Lingus (£345), and British Airways (£363).

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Charleston - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £373). Flying from South Carolina to Manchester in June is currently the most expensive (average of £834). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

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Alternative routes for South Carolina to Manchester

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Top airline flying from South Carolina to Manchester

Discover the top airline that operate flights from South Carolina to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 November 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£488Average£958FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from South Carolina to Manchester become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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