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Cheap flights from South Carolina to Manchester from £259

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
12 Jun — 19 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 May 2026.

Tue 1/909:20
CLT
-
MAN
2 stops28h 10m
Multiple Airlines
Tue 15/907:30
MAN
-
CLT
2 stops18h 27m
Multiple Airlines
Deal found 7/5£622
Wed 26/818:40
CLT
-
MAN
2 stops32h 35m
SWISS
Wed 2/918:40
MAN
-
CLT
2 stops32h 06m
SWISS
Deal found 11/5£636
Sun 4/1018:00
CLT
-
MAN
2 stops17h 05m
British Airways
Tue 13/1020:05
MAN
-
CLT
2 stops24h 00m
British Airways
Deal found 11/5£647
Sun 4/1008:00
CLT
-
MAN
1 stop18h 15m
Delta
Tue 13/1015:00
MAN
-
CLT
1 stop12h 16m
Delta
Deal found 11/5£647
Tue 1/920:15
CLT
-
MAN
1 stop11h 50m
American Airlines
Tue 15/906:55
MAN
-
CLT
2 stops15h 40m
American Airlines
Deal found 7/5£650
Wed 26/823:50
CLT
-
MAN
1 stop16h 55m
American Airlines
Wed 2/907:05
MAN
-
CLT
1 stop14h 00m
American Airlines
Deal found 7/5£650
Wed 26/813:20
CLT
-
MAN
2 stops15h 45m
Delta
Wed 2/910:40
MAN
-
CLT
1 stop18h 17m
Delta
Deal found 7/5£651
Sun 8/1109:20
CLT
-
MAN
1 stop18h 40m
Multiple Airlines
Sun 15/1106:25
MAN
-
CLT
1 stop15h 30m
Multiple Airlines
Deal found 12/5£660
Sun 8/1118:50
CLT
-
MAN
2 stops32h 30m
SWISS
Sun 15/1118:45
MAN
-
CLT
2 stops27h 10m
SWISS
Deal found 12/5£668
Sat 22/806:00
CHS
-
MAN
2 stops24h 45m
Scandinavian Airlines
Wed 26/819:10
MAN
-
CHS
2 stops31h 57m
Scandinavian Airlines
Deal found 11/5£698
Wed 9/918:28
SAV
-
MAN
2 stops16h 02m
American Airlines
Mon 14/908:00
MAN
-
SAV
2 stops18h 53m
American Airlines
Deal found 11/5£723
Wed 5/814:55
GSP
-
MAN
2 stops14h 30m
United Airlines
Wed 12/809:00
MAN
-
GSP
2 stops42h 53m
United Airlines
Deal found 11/5£733

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 13 May 2026.

Round-trip from

£622

One-way from

£259
1/9-15/9
  • 1/9-15/9
  • 4 total stops
  • 46h 37m total
  • South Carolina to Manchester
Search Deals
American Airlines
  • American Airlines
  • 13/9
  • 2 total stops
  • 17h 42m total
  • South Carolina to Manchester
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 May 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 26/8

13:20-10:05

2 stops15h 45m

Manchester

Wed 2/9

10:40-20:23

1 stop14h 43m

£652

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 3/9

09:20-06:30

1 stop16h 10m

Manchester

Sun 13/9

09:00-14:57

1 stop10h 57m

£723

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

10:30-10:25

2 stops18h 55m

Manchester

Wed 12/8

09:00-22:53

2 stops42h 53m

£733

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 9/9

07:25-08:15

1 stop19h 50m

Manchester

Mon 14/9

13:00-22:39

1 stop14h 39m

£791

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 9/9

18:30-14:00

2 stops14h 30m

Manchester

Mon 14/9

13:00-20:53

1 stop12h 53m

£796

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Tue 7/7

11:18-10:25

2 stops18h 07m

Manchester

Tue 21/7

06:05-21:17

2 stops20h 12m

£810

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

14:51-07:15

1 stop11h 24m

Manchester

Wed 12/8

05:55-20:32

2 stops19h 37m

£818

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Tue 9/6

14:43-13:05

2 stops17h 22m

Manchester

Wed 17/6

09:30-10:50

2 stops30h 20m

£825

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Tue 14/7

06:10-10:25

2 stops23h 15m

Manchester

Sat 25/7

06:05-23:34

2 stops22h 29m

£863

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Fri 21/8

15:15-13:25

2 stops17h 10m

Manchester

Sat 19/12

13:25-21:46

1 stop13h 21m

£873

Flights are sorted by cheapest return flights first.

Deals found on 11/5

Showing 1-10 of 45 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £436). Flying from South Carolina to Manchester in March is currently the most expensive (average of £997). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 15h 45m. Delta provides one of the quickest options available for as low as £652. Airlines will cover a distance of 3870 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Myrtle Beach Intl - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £436). Flying from South Carolina to Manchester in March is currently the most expensive (average of £997). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Bradford
Lincoln
Llandudno
Southport
Harrogate
Derby
Stoke-on-Trent
Otley
Warrington
Salford
Lancaster
Shrewsbury
Huddersfield
Telford
Preston
Wakefield
Bolton
Wilmslow
Macclesfield

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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