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Cheap flights from South Carolina to Manchester from £204

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
18 Oct — 25 Oct1
1 adult
1 adult, Economy

Cheap flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 18 September 2025.

Round-trip from

£456

One-way from

£204

Popular in

August

Cheapest in

October

Average price

£544
Virgin Atlantic
  • Virgin Atlantic
  • 10/11-26/11
  • 2 total stops
  • 27h 39m total
  • South Carolina to Manchester
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2/10
  • 2/10
  • 3 total stops
  • 36h 42m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 32% potential increase in price (£288 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 16% potential price decrease (£85 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from South Carolina to Manchester

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 September 2025.

Mon 10/1113:22CLT - MAN
1 stop12h 18mVirgin Atlantic
Wed 26/1113:30MAN - CLT
1 stop15h 21mVirgin Atlantic
Deal found 17/9£456
Mon 10/1118:45CLT - MAN
1 stop30h 55mDelta
Wed 26/1110:25MAN - CLT
2 stops18h 26mDelta
Deal found 17/9£470
Wed 5/1110:02CLT - MAN
1 stop15h 38mDelta
Wed 26/1113:30MAN - CLT
1 stop15h 21mDelta
Deal found 18/9£473
Wed 5/1120:20CLT - MAN
1 stop15h 00mAmerican Airlines
Tue 11/1108:05MAN - CLT
2 stops16h 38mAmerican Airlines
Deal found 17/9£478
Sun 28/906:20CHS - MAN
1 stop21h 15mDelta
Tue 7/1012:35MAN - CHS
1 stop13h 16mDelta
Deal found 16/9£481
Tue 30/912:14HHH - MAN
1 stop15h 21mDelta
Tue 7/1012:35MAN - HHH
1 stop31h 55mDelta
Deal found 16/9£484
Mon 29/912:14HHH - MAN
2 stops15h 31mDelta
Tue 7/1012:35MAN - HHH
1 stop31h 55mDelta
Deal found 16/9£488
Mon 29/918:37CHS - MAN
2 stops13h 48mDelta
Tue 7/1012:35MAN - CHS
1 stop13h 16mDelta
Deal found 16/9£495
Wed 1/1012:56HHH - MAN
2 stops19h 54mAmerican Airlines
Wed 19/1107:50MAN - HHH
2 stops15h 47mAmerican Airlines
Deal found 16/9£496
Wed 5/1114:45CLT - MAN
2 stops15h 10mBritish Airways
Wed 26/1106:10MAN - CLT
2 stops20h 40mBritish Airways
Deal found 16/9£498
Wed 15/1016:33MYR - MAN
2 stops19h 47mUnited Airlines
Wed 22/1006:05MAN - MYR
2 stops15h 51mUnited Airlines
Deal found 17/9£506
Wed 8/1011:29MYR - MAN
2 stops15h 06mDelta
Wed 15/1005:55MAN - MYR
2 stops23h 04mDelta
Deal found 17/9£507

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 September 2025.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

South Carolina

Fly to

Manchester

Route

Depart

Return

Price

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Mon 10/11

18:45-06:40

1 stop30h 55m

Manchester

Wed 26/11

10:25-23:51

2 stops18h 26m

£470

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 5/11

10:02-06:40

1 stop15h 38m

Manchester

Tue 11/11

13:00-22:42

1 stop14h 42m

£473

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 5/11

10:02-06:40

1 stop15h 38m

Manchester

Wed 26/11

13:30-23:51

1 stop15h 21m

£473

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 5/11

20:20-16:20

1 stop15h 00m

Manchester

Tue 11/11

08:05-19:43

2 stops16h 38m

£478

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Sun 28/9

06:20-08:35

1 stop21h 15m

Manchester

Tue 7/10

12:35-20:51

1 stop13h 16m

£481

Hilton Head IslandManchester

HHH - MAN

HHHMAN

Hilton Head Island

Tue 30/9

12:14-08:35

1 stop15h 21m

Manchester

Tue 7/10

12:35-15:30

1 stop31h 55m

£484

Hilton Head IslandManchester

HHH - MAN

HHHMAN

Hilton Head Island

Mon 29/9

12:14-08:45

2 stops15h 31m

Manchester

Tue 7/10

12:35-15:30

1 stop31h 55m

£488

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 26/2

10:00-09:30

2 stops18h 30m

Manchester

Wed 4/3

19:15-23:54

2 stops33h 39m

£490

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Mon 29/9

18:37-13:25

2 stops13h 48m

Manchester

Tue 7/10

12:35-20:51

1 stop13h 16m

£495

Hilton Head IslandManchester

HHH - MAN

HHHMAN

Hilton Head Island

Wed 1/10

12:56-13:50

2 stops19h 54m

Manchester

Wed 19/11

07:50-18:37

2 stops15h 47m

£496

Flights are sorted by cheapest return flights first.

Deals found on 17/9

Showing 1-10 of 41 results
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £117). Flying from South Carolina to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MAN?

Find hourly flight availability from South Carolina to Manchester. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 18 September 2025.

When flying from South Carolina to Manchester, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from South Carolina to Manchester?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 15h 38m. Delta provides one of the quickest options available for as low as £473. Airlines will cover a distance of 3870 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Manchester one-way?

    The cheapet airlines for a one-way flight from South Carolina to Manchester are Virgin Atlantic (£310), American Airlines (£311), and Delta (£317).

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Savannah/Hilton Head - Manchester or Myrtle Beach Intl - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £117). Flying from South Carolina to Manchester in September is currently the most expensive (average of £143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

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Top airline flying from South Carolina to Manchester

Discover the top airline that operate flights from South Carolina to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 September 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£471Average£520FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from South Carolina to Manchester become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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