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Cheap flights from South Carolina to Manchester from £334

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
20 Jun — 27 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 May 2026.

Wed 26/811:50
CLT
-
MAN
1 stop14h 25m
Virgin Atlantic
Wed 2/910:40
MAN
-
CLT
1 stop14h 43m
Virgin Atlantic
Deal found 20/5£422
Wed 26/818:40
CLT
-
MAN
1 stop17h 25m
Multiple Airlines
Wed 2/909:00
MAN
-
CLT
1 stop16h 57m
Multiple Airlines
Deal found 20/5£634
Wed 26/818:40
CLT
-
MAN
1 stop17h 25m
Lufthansa
Wed 2/907:00
MAN
-
CLT
1 stop14h 45m
Lufthansa
Deal found 20/5£643
Wed 26/811:23
CLT
-
MAN
2 stops18h 02m
United Airlines
Wed 2/909:00
MAN
-
CLT
2 stops34h 05m
United Airlines
Deal found 20/5£646
Sun 13/923:05
CLT
-
MAN
1 stop17h 25m
British Airways
Mon 21/920:15
MAN
-
CLT
1 stop25h 25m
British Airways
Deal found 16/5£653
Wed 26/823:50
CLT
-
MAN
1 stop16h 55m
American Airlines
Wed 2/907:05
MAN
-
CLT
1 stop14h 00m
American Airlines
Deal found 18/5£655
Wed 9/912:50
SAV
-
MAN
2 stops28h 55m
Multiple Airlines
Mon 14/920:15
MAN
-
SAV
2 stops31h 27m
Multiple Airlines
Deal found 19/5£698
Mon 16/1118:10
MYR
-
MAN
2 stops17h 20m
British Airways
Fri 27/1109:00
MAN
-
MYR
2 stops19h 55m
British Airways
Deal found 20/5£710
Sat 14/1119:00
SAV
-
MAN
2 stops32h 40m
United Airlines
Wed 25/1106:10
MAN
-
SAV
2 stops18h 02m
United Airlines
Deal found 19/5£732
Wed 5/806:10
GSP
-
MAN
2 stops23h 15m
United Airlines
Wed 12/809:00
MAN
-
GSP
2 stops42h 53m
United Airlines
Deal found 20/5£736
Mon 16/1111:10
MYR
-
MAN
2 stops23h 55m
Delta
Fri 27/1113:25
MAN
-
MYR
1 stop15h 10m
Delta
Deal found 20/5£754
Wed 5/811:18
GSP
-
MAN
3 stops18h 07m
Multiple Airlines
Wed 12/809:00
MAN
-
GSP
2 stops18h 53m
Multiple Airlines
Deal found 20/5£757

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 21 May 2026.

Round-trip from

£422

One-way from

£334

Popular in

August

Cheapest in

April

Average price

£958
Virgin Atlantic
  • Virgin Atlantic
  • 26/8-2/9
  • 2 total stops
  • 29h 08m total
  • South Carolina to Manchester
Search Deals
23/7
  • 23/7
  • 3 total stops
  • 30h 35m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 16% potential increase in price (£127 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£29 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 May 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 26/8

13:17-10:10

2 stops15h 53m

Manchester

Wed 2/9

10:40-20:23

1 stop14h 43m

£426

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 13/9

23:05-21:30

1 stop17h 25m

Manchester

Mon 21/9

20:15-16:40

1 stop25h 25m

£653

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 26/8

13:20-10:05

2 stops15h 45m

Manchester

Wed 2/9

10:40-23:57

1 stop18h 17m

£656

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 26/8

15:00-09:50

2 stops13h 50m

Manchester

Wed 2/9

09:00-15:02

1 stop11h 02m

£656

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Fri 18/9

15:00-10:25

2 stops14h 25m

Manchester

Fri 25/9

09:00-13:50

2 stops33h 50m

£683

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Fri 18/9

13:15-10:00

2 stops15h 45m

Manchester

Fri 25/9

13:00-23:57

1 stop15h 57m

£692

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 9/9

12:50-22:45

2 stops28h 55m

Manchester

Mon 14/9

20:15-22:42

2 stops31h 27m

£700

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 3/9

10:25-06:30

2 stops15h 05m

Manchester

Sun 13/9

09:00-20:57

1 stop16h 57m

£730

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

06:10-10:25

2 stops23h 15m

Manchester

Wed 12/8

09:00-22:53

2 stops42h 53m

£736

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 26/7

19:20-14:00

2 stops13h 40m

Manchester

Thu 6/8

13:00-20:25

1 stop12h 25m

£779

Flights are sorted by cheapest return flights first.

Deals found on 19/5

Showing 1-10 of 44 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £440). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,005). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from South Carolina to Manchester?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 15h 45m. Virgin Atlantic provides one of the quickest options available for as low as £656. Airlines will cover a distance of 3870 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Myrtle Beach Intl - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £440). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,005). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Lincoln
Bradford
Llandudno
Southport
Harrogate
Derby
Stoke-on-Trent
Otley
Warrington
Salford
Lancaster
Shrewsbury
Telford
Huddersfield
Preston
Wakefield
Bolton
Wilmslow
Macclesfield

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Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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