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Cheap flights from South Carolina to Manchester from £149

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
23 Mar — 30 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 February 2026.

Tue 7/409:30
CLT
-
MAN
2 stops20h 35m
Multiple Airlines
Tue 14/407:30
MAN
-
CLT
2 stops18h 30m
Multiple Airlines
Deal found 20/2£451
Tue 8/918:09
CLT
-
MAN
2 stops16h 01m
British Airways
Tue 15/920:05
MAN
-
CLT
2 stops24h 00m
British Airways
Deal found 17/2£465
Tue 8/910:23
CLT
-
MAN
2 stops31h 52m
Lufthansa
Tue 15/907:00
MAN
-
CLT
1 stop14h 45m
Lufthansa
Deal found 17/2£468
Tue 8/920:15
CLT
-
MAN
1 stop13h 55m
American Airlines
Tue 15/912:20
MAN
-
CLT
1 stop11h 40m
American Airlines
Deal found 17/2£481
Tue 5/515:10
CHS
-
MAN
2 stops17h 50m
Delta
Tue 12/513:00
MAN
-
CHS
1 stop14h 56m
Delta
Deal found 19/2£488
Tue 5/516:30
CHS
-
MAN
2 stops15h 35m
American Airlines
Tue 12/506:55
MAN
-
CHS
2 stops16h 54m
American Airlines
Deal found 19/2£491
Wed 18/323:55
CLT
-
MAN
1 stop14h 50m
British Airways
Wed 25/314:50
MAN
-
CLT
1 stop33h 05m
British Airways
Deal found 18/2£503
Tue 5/518:40
CLT
-
MAN
1 stop17h 25m
Lufthansa
Thu 14/507:00
MAN
-
CLT
1 stop14h 45m
Lufthansa
Deal found 18/2£506
Tue 7/417:20
CLT
-
MAN
2 stops16h 50m
British Airways
Tue 14/414:00
MAN
-
CLT
1 stop11h 45m
British Airways
Deal found 20/2£506
Tue 5/516:34
CLT
-
MAN
2 stops15h 31m
British Airways
Mon 18/520:15
MAN
-
CLT
2 stops23h 50m
British Airways
Deal found 17/2£510
Tue 24/311:06
CHS
-
MAN
2 stops26h 29m
British Airways
Thu 2/406:55
MAN
-
CHS
2 stops22h 04m
British Airways
Deal found 17/2£511
Tue 24/306:00
CHS
-
MAN
1 stop20h 40m
Delta
Thu 2/413:45
MAN
-
CHS
2 stops15h 31m
Delta
Deal found 19/2£517

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 21 February 2026.

Round-trip from

£451

One-way from

£149

Popular in

August

Cheapest in

November

Average price

£623
7/4-14/4
  • 7/4-14/4
  • 4 total stops
  • 39h 05m total
  • South Carolina to Manchester
Search Deals
British Airways
  • British Airways
  • 19/8
  • 2 total stops
  • 17h 06m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 26% potential increase in price (£239 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 15% potential price decrease (£91 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 February 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

South Carolina

Fly to

Manchester

Route

Depart

Return

Price

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Tue 5/5

15:10-14:00

2 stops17h 50m

Manchester

Tue 12/5

13:00-22:56

1 stop14h 56m

£488

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Tue 5/5

16:30-13:05

2 stops15h 35m

Manchester

Tue 12/5

06:55-18:49

2 stops16h 54m

£491

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 18/3

23:55-18:45

1 stop14h 50m

Manchester

Wed 25/3

14:50-19:55

1 stop33h 05m

£503

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 5/5

17:23-23:15

2 stops24h 52m

Manchester

Thu 14/5

07:00-16:45

1 stop14h 45m

£509

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Tue 24/3

06:00-06:40

1 stop20h 40m

Manchester

Thu 2/4

13:45-00:16

2 stops15h 31m

£517

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 18/3

12:43-10:30

1 stop17h 47m

Manchester

Wed 25/3

13:40-10:34

2 stops24h 54m

£518

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 6/5

18:40-17:05

1 stop17h 25m

Manchester

Thu 14/5

07:00-16:45

1 stop14h 45m

£525

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

10:30-10:25

2 stops18h 55m

Manchester

Wed 12/8

09:00-17:00

2 stops37h 00m

£526

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Fri 3/4

06:00-10:25

2 stops23h 25m

Manchester

Fri 10/4

06:05-21:25

2 stops20h 20m

£527

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 5/5

23:45-19:00

1 stop14h 15m

Manchester

Mon 18/5

20:15-13:00

1 stop21h 45m

£528

Flights are sorted by cheapest return flights first.

Deals found on 20/2

Showing 1-10 of 47 results
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, December is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £457). Flying from South Carolina to Manchester in March is currently the most expensive (average of £699). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from South Carolina to Manchester?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 14h 50m. Delta provides one of the quickest options available for as low as £503. Airlines will cover a distance of 3870 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Manchester one-way?

    The cheapet airlines for a one-way flight from South Carolina to Manchester are Air France (£169), TUI Airways (£192), and KLM (£288).

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Myrtle Beach Intl - Manchester or Charleston - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, December is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £457). Flying from South Carolina to Manchester in March is currently the most expensive (average of £699). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Bradford
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Derby
Harrogate
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Otley
Southport
Lancaster
Salford
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Huddersfield
Stockport
Macclesfield
Rochdale

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Alternative routes for South Carolina to Manchester

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Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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