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Cheap flights from South Carolina to Manchester from £258

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
6 Jun — 13 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 7 May 2026.

Mon 21/917:55
CLT
-
MAN
1 stop14h 15m
American Airlines
Thu 17/1205:40
MAN
-
CLT
1 stop13h 40m
American Airlines
Deal found 6/5£631
Mon 21/909:20
CLT
-
MAN
2 stops20h 05m
Multiple Airlines
Thu 17/1206:25
MAN
-
CLT
1 stop15h 30m
Multiple Airlines
Deal found 6/5£634
Wed 26/818:40
CLT
-
MAN
2 stops32h 35m
SWISS
Wed 2/918:40
MAN
-
CLT
2 stops27h 05m
SWISS
Deal found 6/5£639
Tue 18/820:15
CLT
-
MAN
1 stop11h 50m
American Airlines
Thu 27/808:50
MAN
-
CLT
1 stop12h 15m
American Airlines
Deal found 3/5£640
Sat 19/920:01
CLT
-
MAN
2 stops21h 34m
British Airways
Mon 28/920:15
MAN
-
CLT
2 stops23h 50m
British Airways
Deal found 4/5£644
Sun 4/1011:45
CLT
-
MAN
1 stop14h 30m
Delta
Tue 13/1015:00
MAN
-
CLT
1 stop12h 16m
Delta
Deal found 3/5£644
Wed 26/823:50
CLT
-
MAN
1 stop16h 55m
American Airlines
Wed 2/910:55
MAN
-
CLT
1 stop13h 05m
American Airlines
Deal found 6/5£648
Wed 26/813:20
CLT
-
MAN
2 stops15h 45m
Delta
Wed 2/910:40
MAN
-
CLT
1 stop12h 37m
Delta
Deal found 6/5£649
Wed 26/806:00
CLT
-
MAN
2 stops23h 25m
United Airlines
Wed 2/909:00
MAN
-
CLT
1 stop11h 02m
United Airlines
Deal found 5/5£650
Wed 9/918:39
SAV
-
MAN
2 stops13h 31m
American Airlines
Mon 14/908:00
MAN
-
SAV
2 stops18h 38m
American Airlines
Deal found 2/5£720
Fri 14/819:41
CHS
-
MAN
2 stops16h 39m
American Airlines
Fri 21/812:15
MAN
-
CHS
2 stops15h 39m
American Airlines
Deal found 6/5£721
Sun 13/920:38
SAV
-
MAN
2 stops17h 42m
American Airlines
Sat 26/907:45
MAN
-
SAV
2 stops19h 08m
American Airlines
Deal found 4/5£728

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 7 May 2026.

Round-trip from

£631

One-way from

£258

Popular in

July

Cheapest in

November

Average price

£899
American Airlines
  • American Airlines
  • 21/9-17/12
  • 2 total stops
  • 27h 55m total
  • South Carolina to Manchester
Search Deals
American Airlines
  • American Airlines
  • 13/9
  • 2 total stops
  • 17h 42m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 26% potential increase in price (£194 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£29 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 7 May 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 4/10

11:45-07:15

1 stop14h 30m

Manchester

Tue 13/10

15:00-22:16

1 stop12h 16m

£644

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 4/10

13:15-08:25

2 stops14h 10m

Manchester

Tue 13/10

15:00-22:16

1 stop12h 16m

£652

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 22/7

11:20-10:25

2 stops18h 05m

Manchester

Wed 26/8

09:00-21:30

2 stops41h 30m

£685

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 4/10

14:20-07:15

1 stop11h 55m

Manchester

Mon 12/10

05:55-18:16

2 stops17h 21m

£688

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Fri 25/9

15:00-10:25

2 stops14h 25m

Manchester

Sun 4/10

09:00-14:57

1 stop10h 57m

£723

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

11:18-10:25

2 stops18h 07m

Manchester

Wed 12/8

09:00-21:17

2 stops41h 17m

£730
Fastest return journey

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

14:51-07:15

1 stop11h 24m

Manchester

Wed 12/8

10:40-18:45

1 stop13h 05m

£764

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

13:28-10:05

2 stops15h 37m

Manchester

Wed 12/8

10:40-22:59

1 stop17h 19m

£768

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Fri 14/8

11:05-13:20

2 stops21h 15m

Manchester

Fri 21/8

09:00-23:53

3 stops19h 53m

£777

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 9/9

07:25-08:15

1 stop19h 50m

Manchester

Mon 14/9

13:00-20:53

1 stop12h 53m

£788

Flights are sorted by cheapest return flights first.

Deals found on 4/5

Showing 1-10 of 48 resultsSorted by cheapest first
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5

Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £435). Flying from South Carolina to Manchester in March is currently the most expensive (average of £993). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from South Carolina to Manchester?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 14h 10m. Delta provides one of the quickest options available for as low as £652. Airlines will cover a distance of 3870 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Myrtle Beach Intl - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £435). Flying from South Carolina to Manchester in March is currently the most expensive (average of £993). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Bradford
Lincoln
Llandudno
Derby
Harrogate
Southport
Stoke-on-Trent
Otley
Warrington
Telford
Salford
Lancaster
Shrewsbury
Huddersfield
Preston
Wakefield
Bolton
Wilmslow
Macclesfield

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Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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