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Cheap flights from South Carolina to Manchester from £216

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
3 Aug — 10 Aug1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 4 July 2026.

Mon 16/1113:00
CHS
-
MAN
2 stops16h 20m
United Airlines
Wed 18/1106:10
MAN
-
CHS
2 stops16h 56m
United Airlines
Deal found 30/6£602
Tue 1/1215:20
MYR
-
MAN
3 stops36h 20m
United Airlines
Fri 4/1206:10
MAN
-
MYR
2 stops33h 27m
United Airlines
Deal found 29/6£603
Wed 11/1117:10
CLT
-
MAN
1 stop10h 05m
Multiple Airlines
Tue 17/1111:30
MAN
-
CLT
1 stop14h 36m
Multiple Airlines
Deal found 29/6£628
Tue 10/1118:50
CLT
-
MAN
2 stops18h 05m
SWISS
Tue 17/1109:10
MAN
-
CLT
2 stops17h 23m
SWISS
Deal found 29/6£631
Tue 10/1118:50
CLT
-
MAN
1 stop17h 05m
United Airlines
Tue 17/1111:30
MAN
-
CLT
2 stops31h 20m
United Airlines
Deal found 29/6£635
Wed 18/1117:10
CLT
-
MAN
1 stop10h 30m
Air Canada
Thu 26/1111:30
MAN
-
CLT
2 stops39h 03m
Air Canada
Deal found 2/7£636
Tue 10/1118:50
CLT
-
MAN
2 stops32h 30m
SWISS
Mon 16/1118:45
MAN
-
CLT
2 stops27h 10m
SWISS
Deal found 29/6£637
Wed 11/1112:20
CLT
-
MAN
2 stops17h 00m
United Airlines
Tue 17/1111:30
MAN
-
CLT
2 stops34h 16m
United Airlines
Deal found 29/6£638
Wed 18/1122:30
CLT
-
MAN
1 stop15h 15m
American Airlines
Wed 25/1108:55
MAN
-
CLT
1 stop12h 10m
American Airlines
Deal found 2/7£639
Tue 10/1122:30
CLT
-
MAN
1 stop15h 15m
Multiple Airlines
Mon 16/1118:50
MAN
-
CLT
1 stop24h 30m
Multiple Airlines
Deal found 29/6£639
Tue 17/1111:45
CLT
-
MAN
1 stop17h 45m
Delta
Thu 26/1113:30
MAN
-
CLT
1 stop33h 42m
Delta
Deal found 2/7£645
Tue 17/1110:07
CLT
-
MAN
2 stops15h 33m
Delta
Fri 27/1113:25
MAN
-
CLT
1 stop29h 06m
Delta
Deal found 2/7£648

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 4 July 2026.

Round-trip from

£602

One-way from

£216

Popular in

August

Cheapest in

April

Average price

£1,120
United Airlines
  • United Airlines
  • 16/11-18/11
  • 4 total stops
  • 33h 16m total
  • South Carolina to Manchester
Search Deals
Aer Lingus
  • Aer Lingus
  • 5/12
  • 2 total stops
  • 14h 35m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 18% potential increase in price (£148 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£27 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 July 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Mon 16/11

13:00-10:20

2 stops16h 20m

Manchester

Wed 18/11

06:10-18:06

2 stops16h 56m

£602

Myrtle BeachManchester

MYR - MAN

MYRMAN

Myrtle Beach Intl

Tue 1/12

15:20-08:40

3 stops36h 20m

Manchester

Fri 4/12

06:10-10:37

2 stops33h 27m

£603

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 18/11

06:00-06:40

1 stop19h 40m

Manchester

Tue 24/11

13:30-11:04

1 stop26h 34m

£645

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 18/11

10:00-06:40

1 stop15h 40m

Manchester

Fri 27/11

13:25-23:53

1 stop15h 28m

£645

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 17/11

11:45-10:30

1 stop17h 45m

Manchester

Wed 25/11

13:30-23:53

1 stop15h 23m

£645

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 17/11

13:00-10:20

2 stops16h 20m

Manchester

Wed 25/11

06:10-18:46

2 stops17h 36m

£656

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 11/11

14:58-10:20

2 stops14h 22m

Manchester

Tue 17/11

11:30-13:39

2 stops31h 09m

£671
Fastest return journey

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 18/11

18:50-10:30

1 stop10h 40m

Manchester

Fri 27/11

13:25-23:59

1 stop15h 34m

£677

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Tue 3/11

07:25-06:40

1 stop18h 15m

Manchester

Wed 18/11

13:00-21:26

1 stop13h 26m

£678

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sun 20/9

12:00-07:15

1 stop14h 15m

Manchester

Fri 18/12

13:25-21:33

1 stop13h 08m

£690

Flights are sorted by cheapest return flights first.

Deals found on 30/6

Showing 1-10 of 44 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £442). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,011). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from South Carolina to Manchester?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 10h 30m. United Airlines provides one of the quickest options available for as low as £636. Airlines will cover a distance of 3870 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Manchester one-way?

    The cheapet airlines for a one-way flight from South Carolina to Manchester are Air France (£180), TUI Airways (£251), and KLM (£290).

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Savannah/Hilton Head - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £442). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,011). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

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Windermere
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Llandudno
Southport
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Lincoln
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Stoke-on-Trent
Otley
Salford
Warrington
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Preston
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Burnley
Lancaster
Macclesfield
Bolton
Crewe

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Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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