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Cheap flights from South Carolina to Manchester from £274

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
25 Apr — 2 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 March 2026.

Mon 7/1215:20
MYR
-
MAN
2 stops42h 30m
United Airlines
Thu 10/1211:50
MAN
-
MYR
2 stops31h 43m
United Airlines
Deal found 23/3£558
Mon 7/1214:54
GSP
-
MAN
2 stops14h 26m
United Airlines
Wed 9/1206:10
MAN
-
GSP
2 stops20h 01m
United Airlines
Deal found 23/3£565
Mon 7/1219:00
SAV
-
MAN
2 stops41h 00m
United Airlines
Thu 10/1211:50
MAN
-
SAV
2 stops27h 47m
United Airlines
Deal found 22/3£575
Wed 22/410:16
CLT
-
MAN
3 stops33h 39m
Multiple Airlines
Wed 29/406:35
MAN
-
CLT
3 stops34h 10m
Multiple Airlines
Deal found 23/3£579
Mon 2/1116:50
SAV
-
MAN
2 stops43h 10m
United Airlines
Thu 5/1106:10
MAN
-
SAV
2 stops33h 27m
United Airlines
Deal found 23/3£579
Mon 20/410:16
CLT
-
MAN
2 stops20h 24m
Multiple Airlines
Mon 27/413:05
MAN
-
CLT
2 stops15h 54m
Multiple Airlines
Deal found 21/3£581
Wed 16/910:23
CLT
-
MAN
2 stops31h 52m
Lufthansa
Wed 30/907:00
MAN
-
CLT
1 stop14h 45m
Lufthansa
Deal found 25/3£586
Wed 16/908:05
CLT
-
MAN
2 stops24h 15m
SWISS
Tue 22/909:00
MAN
-
CLT
2 stops17h 30m
SWISS
Deal found 23/3£596
Mon 27/421:54
CLT
-
MAN
3 stops32h 46m
Multiple Airlines
Mon 11/514:30
MAN
-
CLT
3 stops34h 49m
Multiple Airlines
Deal found 24/3£597
Mon 7/1206:00
CHS
-
MAN
2 stops22h 00m
United Airlines
Wed 9/1206:10
MAN
-
CHS
2 stops16h 56m
United Airlines
Deal found 25/3£602
Fri 18/906:00
CLT
-
MAN
2 stops23h 25m
United Airlines
Sun 20/909:00
MAN
-
CLT
1 stop10h 57m
United Airlines
Deal found 23/3£608
Wed 5/810:30
GSP
-
MAN
2 stops18h 55m
United Airlines
Wed 12/809:00
MAN
-
GSP
2 stops41h 17m
United Airlines
Deal found 23/3£656

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 26 March 2026.

Round-trip from

£579

One-way from

£274

Popular in

April

Cheapest in

November

Average price

£1,008
22/4-29/4
  • 22/4-29/4
  • 6 total stops
  • 67h 49m total
  • South Carolina to Manchester
Search Deals
British Airways
  • British Airways
  • 13/7
  • 2 total stops
  • 15h 55m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 19% potential increase in price (£143 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£25 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 26 March 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Wed 16/9

06:00-08:15

1 stop21h 15m

Manchester

Wed 30/9

14:55-10:07

1 stop24h 12m

£619

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

14:55-10:25

2 stops14h 30m

Manchester

Wed 12/8

09:00-21:17

2 stops41h 17m

£656

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Fri 1/5

17:59-22:25

2 stops23h 26m

Manchester

Mon 4/5

17:35-16:57

2 stops52h 22m

£663

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Mon 20/4

08:05-10:25

2 stops21h 20m

Manchester

Mon 27/4

10:35-16:45

1 stop35h 10m

£664

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Mon 20/4

06:30-10:25

2 stops22h 55m

Manchester

Tue 5/5

06:05-22:58

2 stops21h 53m

£710

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

19:49-06:30

2 stops29h 41m

Manchester

Wed 12/8

09:00-23:05

3 stops19h 05m

£713

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Thu 7/5

10:40-10:25

2 stops18h 45m

Manchester

Thu 14/5

06:05-18:58

2 stops17h 53m

£730

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Sun 3/5

10:33-10:25

2 stops18h 52m

Manchester

Sun 10/5

09:45-17:10

2 stops36h 25m

£739

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Tue 9/6

10:00-23:15

2 stops32h 15m

Manchester

Wed 17/6

06:05-23:52

2 stops22h 47m

£759

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Mon 20/4

11:06-08:50

1 stop16h 44m

Manchester

Tue 5/5

15:00-09:09

2 stops23h 09m

£767

Flights are sorted by cheapest return flights first.

Deals found on 23/3

Showing 1-10 of 36 resultsSorted by cheapest first
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3
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £451). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from South Carolina to Manchester?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 14h 30m. Delta provides one of the quickest options available for as low as £656. Airlines will cover a distance of 3936 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Manchester one-way?

    The cheapet airlines for a one-way flight from South Carolina to Manchester are Air France (£170), TUI Airways (£239), and KLM (£290).

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Myrtle Beach Intl - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £451). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
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Llandudno
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Derby
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Southport
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Stoke-on-Trent
Salford
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Wakefield
Shrewsbury
Bolton
Macclesfield
Stockport

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Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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