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Cheap flights from South Carolina to Manchester from £337

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
8 Jan — 15 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 December 2025.

Mon 8/1206:39GSP - MAN
2 stops26h 21mBritish Airways
Sun 11/114:50MAN - GSP
2 stops32h 06mBritish Airways
Deal found 7/12£606
Wed 10/1206:45GSP - MAN
2 stops20h 10mDelta
Sun 14/1210:25MAN - GSP
2 stops29h 50mDelta
Deal found 7/12£614
Mon 8/1212:17GSP - MAN
2 stops18h 28mAmerican Airlines
Mon 15/1209:40MAN - GSP
2 stops17h 21mAmerican Airlines
Deal found 7/12£617
Mon 8/1218:29GSP - MAN
2 stops16h 36mDelta
Sun 14/1210:25MAN - GSP
2 stops27h 37mDelta
Deal found 7/12£618
Wed 10/1210:08GSP - MAN
1 stop19h 22mDelta
Tue 16/1213:40MAN - GSP
2 stops15h 00mDelta
Deal found 7/12£618
Sun 14/1222:50CLT - MAN
1 stop14h 15mAmerican Airlines
Thu 25/1211:40MAN - CLT
1 stop12h 20mAmerican Airlines
Deal found 7/12£621
Sun 14/1218:20CLT - MAN
2 stops16h 15mBritish Airways
Thu 25/1207:45MAN - CLT
2 stops16h 25mBritish Airways
Deal found 7/12£622
Tue 9/1205:35GSP - MAN
1 stop23h 55mDelta
Sun 14/1209:05MAN - GSP
2 stops19h 35mDelta
Deal found 7/12£622
Tue 9/1207:59GSP - MAN
2 stops19h 21mDelta
Mon 15/1211:00MAN - GSP
2 stops15h 42mDelta
Deal found 7/12£625
Sun 7/1219:36GSP - MAN
2 stops39h 59mDelta
Mon 15/1213:40MAN - GSP
2 stops15h 00mDelta
Deal found 7/12£630
Tue 9/1213:50GSP - MAN
2 stops13h 45mMultiple Airlines
Mon 15/1209:40MAN - GSP
2 stops17h 21mMultiple Airlines
Deal found 9/12£636
Mon 15/1218:25CLT - MAN
2 stops14h 35mBritish Airways
Wed 24/1206:10MAN - CLT
2 stops18h 00mBritish Airways
Deal found 7/12£641

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 9 December 2025.

Round-trip from

£465

One-way from

£337

Popular in

August

Cheapest in

November

Average price

£1,013
British Airways
  • British Airways
  • 29/1-3/2
  • 4 total stops
  • 47h 00m total
  • South Carolina to Manchester
Search Deals
4/1
  • 4/1
  • 3 total stops
  • 40h 33m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 32% potential increase in price (£300 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 16% potential price decrease (£89 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 December 2025.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

South Carolina

Fly to

Manchester

Route

Depart

Return

Price

Myrtle BeachManchester

MYR - MAN

MYRMAN

Myrtle Beach Intl

Thu 29/1

18:54-10:30

1 stop10h 36m

Manchester

Tue 3/2

13:30-23:41

1 stop15h 11m

£467

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Fri 23/1

14:13-10:20

2 stops15h 07m

Manchester

Tue 27/1

06:10-14:47

2 stops37h 37m

£479

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 21/1

14:55-10:20

2 stops14h 25m

Manchester

Wed 28/1

06:10-10:16

2 stops33h 06m

£479

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Fri 30/1

06:05-10:20

2 stops23h 15m

Manchester

Tue 3/2

06:10-14:50

2 stops37h 40m

£479

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Tue 5/5

18:04-13:10

2 stops14h 06m

Manchester

Thu 14/5

08:10-16:00

1 stop12h 50m

£483

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Thu 8/1

10:51-23:20

2 stops31h 29m

Manchester

Tue 13/1

11:15-23:48

2 stops17h 33m

£483

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 14/1

14:55-10:20

2 stops14h 25m

Manchester

Sun 18/1

06:00-14:19

2 stops37h 19m

£488

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 7/1

17:34-12:20

2 stops37h 46m

Manchester

Tue 13/1

06:25-20:47

2 stops19h 22m

£491

SavannahManchester

SAV - MAN

SAVMAN

Savannah/Hilton Head

Wed 4/3

07:00-18:35

2 stops30h 35m

Manchester

Tue 10/3

10:10-22:02

2 stops39h 52m

£497

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Thu 26/2

14:26-09:30

2 stops38h 04m

Manchester

Wed 4/3

10:10-22:30

2 stops41h 20m

£500

Flights are sorted by cheapest return flights first.

Deals found on 7/12

Showing 1-10 of 38 results
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Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £368). Flying from South Carolina to Manchester in June is currently the most expensive (average of £824). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 10h 36m. Delta provides one of the quickest options available for as low as £467. Airlines will cover a distance of 3864 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Charleston - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £368). Flying from South Carolina to Manchester in June is currently the most expensive (average of £824). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

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Telford
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Huddersfield

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Alternative routes for South Carolina to Manchester

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Top airline flying from South Carolina to Manchester

Discover the top airline that operate flights from South Carolina to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 December 2025.
AirlineCheapestAverageFlexibilityOn-time
Virgin AtlanticCheapest£482Average£645FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights

Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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