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Cheap flights from South Carolina to Manchester from £196

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAN
11 Apr — 18 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from South Carolina to Manchester

Enter your travel dates to find the best prices.

Cheapest flights from South Carolina to Manchester
Explore the most affordable flight options available from South Carolina to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 12 March 2026.

Mon 30/1119:40
CHS
-
MAN
2 stops33h 40m
United Airlines
Thu 3/1206:10
MAN
-
CHS
2 stops16h 56m
United Airlines
Deal found 8/3£493
Mon 30/1109:20
CLT
-
MAN
1 stop18h 40m
United Airlines
Thu 3/1211:50
MAN
-
CLT
2 stops31h 00m
United Airlines
Deal found 8/3£523
Tue 20/1023:10
CLT
-
MAN
1 stop14h 50m
American Airlines
Tue 3/1106:15
MAN
-
CLT
1 stop14h 50m
American Airlines
Deal found 9/3£524
Mon 30/1109:20
CLT
-
MAN
1 stop18h 40m
Air Canada
Thu 3/1211:50
MAN
-
CLT
1 stop14h 09m
Air Canada
Deal found 8/3£533
Mon 19/1018:59
CLT
-
MAN
2 stops14h 01m
Multiple Airlines
Tue 3/1113:30
MAN
-
CLT
1 stop13h 03m
Multiple Airlines
Deal found 9/3£534
Tue 20/1018:40
CLT
-
MAN
1 stop17h 25m
Lufthansa
Tue 3/1106:25
MAN
-
CLT
1 stop15h 30m
Lufthansa
Deal found 10/3£539
Mon 19/1018:59
CLT
-
MAN
2 stops14h 01m
Multiple Airlines
Wed 4/1111:00
MAN
-
CLT
2 stops15h 50m
Multiple Airlines
Deal found 9/3£540
Tue 7/419:30
CLT
-
MAN
2 stops22h 45m
Lufthansa
Tue 14/407:00
MAN
-
CLT
1 stop14h 45m
Lufthansa
Deal found 8/3£550
Mon 9/1115:20
MYR
-
MAN
2 stops14h 00m
United Airlines
Fri 13/1106:10
MAN
-
MYR
2 stops37h 23m
United Airlines
Deal found 8/3£580
Wed 5/810:30
GSP
-
MAN
2 stops18h 55m
United Airlines
Wed 12/809:00
MAN
-
GSP
2 stops37h 02m
United Airlines
Deal found 8/3£580
Tue 15/910:46
GSP
-
MAN
2 stops18h 39m
United Airlines
Tue 22/906:05
MAN
-
GSP
2 stops17h 54m
United Airlines
Deal found 7/3£585
Mon 30/1113:14
SAV
-
MAN
2 stops16h 06m
United Airlines
Thu 3/1211:50
MAN
-
SAV
2 stops38h 20m
United Airlines
Deal found 11/3£596

Find flight deals from South Carolina to Manchester

Keep the following information in mind while searching for South Carolina to Manchester flight deals. Data was last updated 12 March 2026.

Round-trip from

£550

One-way from

£196

Popular in

April

Cheapest in

November

Average price

£1,006
Lufthansa
  • Lufthansa
  • 7/4-14/4
  • 3 total stops
  • 37h 30m total
  • South Carolina to Manchester
Search Deals
American Airlines
  • American Airlines
  • 21/7
  • 1 total stop
  • 14h 00m total
  • South Carolina to Manchester
Search Deals
Highest demand for flights based on searches. 19% potential increase in price (£144 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease (£25 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from South Carolina to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 12 March 2026.
Use the filters below to find and compare flights from South Carolina to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

10:30-10:25

2 stops18h 55m

Manchester

Wed 12/8

09:00-17:02

2 stops37h 02m

£580

Hilton Head IslandManchester

HHH - MAN

HHHMAN

Hilton Head Island

Tue 21/4

15:05-10:25

2 stops14h 20m

Manchester

Tue 28/4

06:05-14:16

2 stops37h 11m

£613

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Tue 24/3

08:15-10:20

2 stops22h 05m

Manchester

Thu 2/4

06:05-18:59

2 stops17h 54m

£632

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sat 18/7

19:44-09:50

2 stops33h 06m

Manchester

Tue 11/8

10:35-16:45

1 stop35h 10m

£656

CharlestonManchester

CHS - MAN

CHSMAN

Charleston

Tue 24/3

18:09-16:30

2 stops18h 21m

Manchester

Thu 2/4

06:55-23:01

2 stops21h 06m

£661

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Wed 5/8

19:49-06:30

2 stops29h 41m

Manchester

Wed 12/8

09:00-23:05

3 stops19h 05m

£676

CharlotteManchester

CLT - MAN

CLTMAN

Charlotte Douglas

Sat 25/4

16:34-17:05

2 stops19h 31m

Manchester

Sat 2/5

10:05-08:36

2 stops27h 31m

£680

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Thu 14/5

07:00-09:45

2 stops21h 45m

Manchester

Tue 19/5

06:55-10:35

2 stops32h 40m

£681

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Sun 26/4

20:16-19:20

2 stops18h 04m

Manchester

Sun 3/5

07:00-19:38

2 stops17h 38m

£694

GreenvilleManchester

GSP - MAN

GSPMAN

Greenville

Sun 26/4

14:53-09:50

2 stops13h 57m

Manchester

Sun 3/5

10:35-09:47

2 stops28h 12m

£699

Flights are sorted by cheapest return flights first.

Deals found on 10/3

Showing 1-10 of 54 resultsSorted by cheapest first
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6

Best time to book a flight from South Carolina to Manchester

Have a flexible travel schedule? Discover the best time to fly to Manchester from South Carolina with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Manchester

What is the cheapest month to book a flight from South Carolina to Manchester?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £450). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,006). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Manchester from South Carolina?

    Most people fly into Manchester (MAN) if they book a flight to Manchester from South Carolina. Manchester is conveniently located just 8.9 mi from Manchester’s city center.

  • How long is the flight from South Carolina to Manchester?

    A quick flight from South Carolina to Manchester can take about 18h 21m. United Airlines provides one of the quickest options available for as low as £661. Airlines will cover a distance of 3948 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Manchester?

    While some choose either Greenville - Manchester or Myrtle Beach Intl - Manchester, Charlotte Douglas - Manchester is the most popular route from South Carolina to Manchester.

  • Can I find deals for flights from South Carolina to Manchester that include hotel bookings?

    Yes. In addition to deals on South Carolina to Manchester flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Manchester?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Manchester.

  • Can I find deals for business class flights from South Carolina to Manchester?

    Yes. Cheapflights offers flight deals from South Carolina to Manchester by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Manchester?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Manchester (average of £450). Flying from South Carolina to Manchester in March is currently the most expensive (average of £1,006). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
Windermere
Llandudno
Lincoln
Bradford
Derby
Harrogate
Stoke-on-Trent
Southport
Otley
Salford
Lancaster
Telford
Warrington
Bolton
Preston
Wakefield
Huddersfield
Macclesfield
Rochdale
Stockport

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Fly with Cheapflights

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How does Cheapflights help users find flights from South Carolina to Manchester?

When you search for this flight from South Carolina to Manchester, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from South Carolina to Manchester?

Millions of users choose and trust Cheapflights to book the best flight deals from South Carolina to Manchester for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from South Carolina to Manchester with no change fees?

Certainly. Search results for flights to Manchester from South Carolina shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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