Cheap flights from London Heathrow Airport to Missouri from £348

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
LHR — STL
22 Jan — 29 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to Missouri
Explore the most affordable flight options available from Heathrow to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 December 2025.

Thu 25/1219:10LHR - STL
1 stop20h 21mAmerican Airlines
Sun 18/112:01STL - LHR
1 stop12h 59mAmerican Airlines
Deal found 21/12£1,107
Fri 26/1208:50LHR - MCI
2 stops20h 58mAer Lingus
Thu 1/105:12MCI - LHR
2 stops44h 53mAer Lingus
Deal found 22/12£1,111
Thu 25/1211:55LHR - STL
1 stop17h 01mAmerican Airlines
Thu 8/113:35STL - LHR
1 stop12h 40mAmerican Airlines
Deal found 21/12£1,137
Thu 25/1207:30LHR - STL
2 stops18h 00mBritish Airways
Sun 18/118:44STL - LHR
1 stop31h 31mBritish Airways
Deal found 22/12£1,173
Thu 25/1210:00LHR - STL
2 stops16h 41mDelta
Sun 18/110:19STL - LHR
2 stops15h 46mDelta
Deal found 22/12£1,194
Thu 25/1207:30LHR - STL
2 stops18h 00mBritish Airways
Thu 8/112:11STL - LHR
1 stop12h 19mBritish Airways
Deal found 21/12£1,222
Thu 25/1206:30LHR - STL
2 stops15h 58mVirgin Atlantic
Thu 8/109:59STL - LHR
2 stops14h 51mVirgin Atlantic
Deal found 21/12£1,224
Tue 23/1220:15LHR - MCI
2 stops27h 26mLufthansa
Mon 29/1217:46MCI - LHR
1 stop11h 04mLufthansa
Deal found 21/12£1,236
Mon 22/1215:00LHR - STL
1 stop13h 56mAmerican Airlines
Sat 31/115:54STL - LHR
1 stop14h 06mAmerican Airlines
Deal found 22/12£1,252
Tue 23/1206:30LHR - MCI
2 stops34h 52mMultiple Airlines
Mon 29/1211:53MCI - LHR
2 stops23h 27mMultiple Airlines
Deal found 21/12£1,257
Mon 22/1213:00LHR - STL
1 stop13h 41mMultiple Airlines
Sat 31/117:04STL - LHR
2 stops55h 16mMultiple Airlines
Deal found 22/12£1,295
Fri 26/1212:10LHR - MCI
2 stops17h 38mMultiple Airlines
Thu 1/113:48MCI - LHR
1 stop11h 07mMultiple Airlines
Deal found 22/12£1,300

Find flight deals from Heathrow to Missouri

Keep the following information in mind while searching for Heathrow to Missouri flight deals. Data was last updated 23 December 2025.

Round-trip from

£403

One-way from

£348

Popular in

December

Cheapest in

March

Average price

£1,018

Good round-trip deal

£580 or less
Austrian Airlines
  • Austrian Airlines
  • 4/2-11/2
  • 3 total stops
  • 45h 14m total
  • London to Missouri
Lufthansa
  • Lufthansa
  • 6/5
  • 1 total stop
  • 12h 55m total
  • London to Missouri
Highest demand for flights based on searches. 4% potential increase in price (£24 potential increase over avg. return price).
Cheapest flight prices on average. 3% potential price decrease (£20 potential savings vs. average return price).
Average for round-trip flights in December 2025
Price to beat on a round-trip flight from London Heathrow to Missouri.

Cheapflights Fare Finder

 
Customise your flight search to find flights from Heathrow to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 23 December 2025.
Use the filters below to find and compare flights from London Heathrow Airport to Missouri that are best for you.

Fly from

Heathrow

Fly to

Missouri

Route

Depart

Return

Price

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Wed 4/2

15:00-22:59

1 stop13h 59m

Lambert-St Louis

Wed 11/2

14:54-07:00

1 stop10h 06m

£450

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Fri 1/5

06:30-13:25

1 stop12h 55m

Lambert-St Louis

Tue 5/5

14:20-08:35

1 stop12h 15m

£453

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Mon 2/2

09:00-19:27

2 stops16h 27m

Lambert-St Louis

Mon 9/2

13:15-11:15

1 stop16h 00m

£459

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Thu 5/2

09:00-22:58

2 stops19h 58m

Lambert-St Louis

Thu 12/2

11:25-06:40

2 stops13h 15m

£459

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Wed 4/2

09:00-19:27

2 stops16h 27m

Lambert-St Louis

Wed 11/2

12:44-09:10

2 stops14h 26m

£459

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Tue 13/1

08:30-22:58

2 stops20h 28m

Lambert-St Louis

Fri 23/1

12:44-06:40

1 stop11h 56m

£463

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Mon 12/1

09:00-15:29

2 stops36h 29m

Lambert-St Louis

Mon 26/1

16:05-08:30

1 stop10h 25m

£468

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Mon 12/1

11:45-18:34

1 stop12h 49m

Lambert-St Louis

Mon 26/1

14:54-07:00

1 stop10h 06m

£470

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Wed 13/5

06:30-13:25

1 stop12h 55m

Lambert-St Louis

Sun 17/5

07:45-06:45

1 stop17h 00m

£471

LondonSt. Louis

LHR - STL

LHRSTL

London Heathrow

Fri 6/2

12:00-23:59

1 stop17h 59m

Lambert-St Louis

Sat 14/2

16:05-08:30

1 stop10h 25m

£474

Flights are sorted by cheapest return flights first.

Deals found on 20/12

Showing 1-10 of 47 results
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Best time to book a flight from Heathrow to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Heathrow with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to Missouri

What is the cheapest month to book a flight from London Heathrow Airport to Missouri?

Currently, September is the cheapest month in which you can book a flight from London Heathrow Airport to Missouri (average of £402). Flying from London Heathrow Airport to Missouri in July is currently the most expensive (average of £606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LHR to MO?

Find hourly flight availability from Heathrow to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 23 December 2025.

One of the essential ways to save on airfare from London Heathrow Airport to Missouri is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 22% on airfare.

What is the cheapest day to fly from London Heathrow Airport to Missouri?

Use this chart to determine the cheapest time to fly return from Heathrow to Missouri. Price data was last updated on 16 December 2024.

Travellers seeking maximum savings on their London Heathrow Airport to Missouri flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost for a return flight from London Heathrow Airport to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 23 December 2025.
See what other customers who have flown with Finnair, Virgin Atlantic, andUnited Airlines from London Heathrow Airport to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.9

Food

6.7

Boarding

7.6

Overall

7.6

Comfort

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2025

FRA - DFW

I was lucky I had a seet without no one next to me My vegetarian meal was excellent. The service very good. Although there was a lot of turbulences during the flight, the landing was very soft and took away all our apprehension.

Entertainment

6.9

Food

6.7

Boarding

7.6

Overall

7.6

Comfort

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2025

FRA - DFW

I was lucky I had a seet without no one next to me My vegetarian meal was excellent. The service very good. Although there was a lot of turbulences during the flight, the landing was very soft and took away all our apprehension.

Entertainment

6.9

Food

6.7

Boarding

7.6

Overall

7.6

Comfort

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2025

FRA - DFW

I was lucky I had a seet without no one next to me My vegetarian meal was excellent. The service very good. Although there was a lot of turbulences during the flight, the landing was very soft and took away all our apprehension.

Entertainment

6.9

Food

6.7

Boarding

7.6

Overall

7.6

Comfort

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2025

FRA - DFW

I was lucky I had a seet without no one next to me My vegetarian meal was excellent. The service very good. Although there was a lot of turbulences during the flight, the landing was very soft and took away all our apprehension.

Entertainment

6.9

Food

6.7

Boarding

7.6

Overall

7.6

Comfort

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2025

FRA - DFW

I was lucky I had a seet without no one next to me My vegetarian meal was excellent. The service very good. Although there was a lot of turbulences during the flight, the landing was very soft and took away all our apprehension.

Entertainment

6.9

Food

6.7

Boarding

7.6

Overall

7.6

Comfort

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2025

FRA - DFW

I was lucky I had a seet without no one next to me My vegetarian meal was excellent. The service very good. Although there was a lot of turbulences during the flight, the landing was very soft and took away all our apprehension.

Related info for your journey

Find useful and relevant information for your journey from Heathrow to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from London Heathrow Airport to Missouri?

    There are many flights that can get you from London Heathrow Airport to Missouri in 13h 59m. Fly via British Airways, United Airlines, or Scandinavian Airlines to get the fastest option. There are 4186 mi between London Heathrow Airport and Missouri. Both multi-stop and direct flights can be found to your destination and back.

  • What are the cheapest airlines to fly from London Heathrow Airport to Missouri one-way?

    £342 is the cheapest one-way deal found within the past few days, from British Airways. You may also be able to find cheap deals on Finnair and Lufthansa, with prices starting from £539 and £554, respectively.

  • What are the most popular routes from London Heathrow Airport to Missouri?

  • What are the cheapest flights from London Heathrow Airport to Missouri?

    Looking at all options, your cheapest flight can be booked for £537. While the most popular route (London Heathrow - Lambert-St Louis) can be booked for £453 on average, our data indicates £594 when flying from London Heathrow Airport to Missouri.

  • Can I find deals for flights from Heathrow to Missouri that include hotel bookings?

    Yes. In addition to deals on Heathrow to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to Missouri.

  • Can I find deals for business class flights from Heathrow to Missouri?

    Yes. Cheapflights offers flight deals from Heathrow to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London Heathrow Airport to Missouri?

    Currently, September is the cheapest month in which you can book a flight from London Heathrow Airport to Missouri (average of £402). Flying from London Heathrow Airport to Missouri in July is currently the most expensive (average of £606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Heathrow to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Heathrow to Missouri

Discover the top 10 airlines that operate flights from Heathrow to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 23 December 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest£171Average£826FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
British AirwaysCheapest£480Average£807FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapest£502Average£860FlexibilityNo cancel feeOn-time75%
Search KLM flights
FinnairCheapest£504Average£669FlexibilityNo cancel feeOn-time76%
Search Finnair flights
IberiaCheapest£523Average£719FlexibilityNo cancel feeOn-time77%
Search Iberia flights
Scandinavian AirlinesCheapest£547Average£752FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
Virgin AtlanticCheapest£560Average£895FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
Air CanadaCheapest£602Average£747FlexibilityNo cancel feeOn-time67%
Search Air Canada flights
United AirlinesCheapest£615Average£779FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£633Average£785FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Heathrow to Missouri?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Heathrow to Missouri. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Heathrow to Missouri?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Missouri from Heathrow.

Can Cheapflights find flights from Heathrow to Missouri with no change fees?

Certainly. Search results for flights to Missouri from Heathrow shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Heathrow to Missouri become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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