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Cheap flights from Manchester to Missouri from £326

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STL
20 Feb — 27 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Missouri
Explore the most affordable flight options available from Manchester to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 21 January 2026.

Thu 5/206:00
MAN
-
STL
2 stops36h 29m
United Airlines
Mon 9/211:20
STL
-
MAN
2 stops15h 25m
United Airlines
Deal found 18/1£557
Thu 3/908:50
MAN
-
STL
2 stops30h 24m
Finnair
Wed 9/918:55
STL
-
MAN
2 stops20h 50m
Finnair
Deal found 20/1£572
Thu 3/908:50
MAN
-
STL
2 stops16h 33m
British Airways
Wed 9/909:46
STL
-
MAN
2 stops18h 04m
British Airways
Deal found 19/1£584
Thu 3/905:55
MAN
-
STL
2 stops21h 09m
United Airlines
Wed 9/915:30
STL
-
MAN
1 stop12h 40m
United Airlines
Deal found 19/1£596
Tue 31/312:20
MAN
-
STL
2 stops17h 28m
British Airways
Wed 15/412:11
STL
-
MAN
2 stops15h 39m
British Airways
Deal found 20/1£667
Thu 5/310:25
MAN
-
STL
1 stop19h 34m
Multiple Airlines
Thu 12/307:47
STL
-
MAN
1 stop19h 08m
Multiple Airlines
Deal found 19/1£678
Wed 1/407:55
MAN
-
STL
2 stops19h 16m
British Airways
Tue 14/412:11
STL
-
MAN
2 stops18h 54m
British Airways
Deal found 20/1£679
Thu 5/219:15
MAN
-
MCI
2 stops32h 47m
Scandinavian Airlines
Fri 20/213:23
MCI
-
MAN
2 stops38h 07m
Scandinavian Airlines
Deal found 19/1£694
Fri 3/419:10
MAN
-
MCI
2 stops35h 02m
Scandinavian Airlines
Sat 25/412:22
MCI
-
MAN
2 stops38h 33m
Scandinavian Airlines
Deal found 19/1£706
Thu 26/206:00
MAN
-
MCI
2 stops19h 42m
United Airlines
Mon 2/311:32
MCI
-
MAN
2 stops15h 13m
United Airlines
Deal found 18/1£813
Fri 25/910:30
MAN
-
SGF
2 stops15h 47m
British Airways
Tue 29/918:30
SGF
-
MAN
2 stops18h 35m
British Airways
Deal found 18/1£848
Thu 5/213:30
MAN
-
MCI
1 stop14h 32m
Virgin Atlantic
Fri 20/213:23
MCI
-
MAN
1 stop15h 07m
Virgin Atlantic
Deal found 19/1£851

Find flight deals from Manchester to Missouri

Keep the following information in mind while searching for Manchester to Missouri flight deals. Data was last updated 21 January 2026.

Round-trip from

£557

One-way from

£326

Popular in

August

Cheapest in

December

Average price

£784
United Airlines
  • United Airlines
  • 5/2-9/2
  • 4 total stops
  • 51h 54m total
  • Manchester to Missouri
Search Deals
2/2
  • 2/2
  • 3 total stops
  • 58h 28m total
  • Manchester to Missouri
Search Deals
Highest demand for flights based on searches. 12% potential increase in price (£90 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2026.
Use the filters below to find and compare flights from Manchester to Missouri that are best for you.

Fly from

Manchester

Fly to

Missouri

Route

Depart

Return

Price

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 5/2

06:00-12:29

2 stops36h 29m

Lambert-St Louis

Mon 9/2

11:20-08:45

2 stops15h 25m

£557

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Tue 31/3

12:20-23:48

2 stops17h 28m

Lambert-St Louis

Tue 14/4

12:11-13:05

2 stops18h 54m

£667

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 5/3

10:25-23:59

1 stop19h 34m

Lambert-St Louis

Thu 12/3

07:47-07:55

1 stop19h 08m

£678

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 1/4

07:55-21:11

2 stops19h 16m

Lambert-St Louis

Tue 14/4

12:11-13:05

2 stops18h 54m

£679

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Tue 31/3

13:00-21:06

1 stop14h 06m

Lambert-St Louis

Wed 15/4

17:59-14:00

2 stops14h 01m

£686

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Thu 5/2

19:15-22:02

2 stops32h 47m

Kansas City

Fri 20/2

13:23-09:30

2 stops38h 07m

£694

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 1/4

10:40-17:53

1 stop13h 13m

Lambert-St Louis

Tue 14/4

17:59-14:00

2 stops14h 01m

£697

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 1/4

10:40-17:53

1 stop13h 13m

Lambert-St Louis

Wed 15/4

17:59-14:00

2 stops14h 01m

£697

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Fri 3/4

19:10-00:12

2 stops35h 02m

Kansas City

Sat 25/4

12:22-08:55

2 stops38h 33m

£706

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 2/4

08:50-21:11

2 stops18h 21m

Lambert-St Louis

Wed 15/4

12:11-09:50

2 stops15h 39m

£709

Flights are sorted by cheapest return flights first.

Deals found on 18/1

Showing 1-10 of 27 results
1
2
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Best time to book a flight from Manchester to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Missouri

What is the cheapest month to book a flight from Manchester to Missouri?

Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £506). Flying from Manchester to Missouri in August is currently the most expensive (average of £790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 21 January 2026.
Get a feel of what it's like to fly with KLM, Finnair, andVirgin Atlantic from Manchester to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Food

7.3

Overall

7.7

Crew

8.4

Comfort

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7.7
Good
1,442 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Food

7.3

Overall

7.7

Crew

8.4

Comfort

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Finnair
7.6
Good
1,353 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Food

7.3

Overall

7.7

Crew

8.4

Comfort

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Virgin Atlantic
7.5
Good
678 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Food

7.3

Overall

7.7

Crew

8.4

Comfort

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Aer Lingus
7.2
Good
1,437 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Food

7.3

Overall

7.7

Crew

8.4

Comfort

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
British Airways
6.7
Okay
7,690 reviews
KLM
7.7
Good
1,442 reviews
Check prices

Entertainment

7.1

Food

7.3

Overall

7.7

Crew

8.4

Comfort

7.6

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Missouri?

    If you book a flight to Missouri from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MAN) is located 8.9 mi from the center of Manchester.

  • How long is the flight from Manchester to Missouri?

    Airlines like United Airlines, British Airways, and Scandinavian Airlines fly from Manchester to Missouri in about 17h 28m. The time it takes to get you to your destination can typically vary by up to 19h 01m. The distance between Manchester and Missouri is about 4061 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Manchester to Missouri?

    While some choose either Manchester - Lambert-St Louis or Manchester - Columbia Regional, Manchester - Kansas City is the most popular route from Manchester to Missouri.

  • Can I find deals for flights from Manchester to Missouri that include hotel bookings?

    Yes. In addition to deals on Manchester to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Missouri.

  • Can I find deals for business class flights from Manchester to Missouri?

    Yes. Cheapflights offers flight deals from Manchester to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Missouri?

    Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £506). Flying from Manchester to Missouri in August is currently the most expensive (average of £790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Manchester to Missouri

Discover the top 10 airlines that operate flights from Manchester to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 21 January 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest£482Average£919FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
FinnairCheapest£517Average£634FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£564Average£809FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Scandinavian AirlinesCheapest£580Average£709FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
Virgin AtlanticCheapest£655Average£919FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£667Average£954FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£676Average£836FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Aer LingusCheapest£686Average£1,043FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights
LufthansaCheapest£734Average£853FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
American AirlinesCheapest£837Average£1,036FlexibilityNo cancel feeOn-time71%
Search American Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Missouri?

Deals for Manchester to Missouri flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Missouri?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Missouri from Manchester.

Can Cheapflights find flights from Manchester to Missouri with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to Missouri with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Missouri become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Missouri on Cheapflights with our Price Alert feature and get notified when better prices are available.

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