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Cheap flights from Manchester to Missouri from £494

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STL
28 Feb — 7 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Missouri
Explore the most affordable flight options available from Manchester to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 January 2026.

Thu 5/206:10
MAN
-
STL
2 stops19h 17m
United Airlines
Mon 9/209:57
STL
-
MAN
2 stops16h 48m
United Airlines
Deal found 26/1£555
Thu 3/910:50
MAN
-
STL
2 stops27h 15m
British Airways
Wed 9/909:46
STL
-
MAN
2 stops21h 24m
British Airways
Deal found 27/1£581
Fri 13/313:25
MAN
-
STL
1 stop15h 33m
Virgin Atlantic
Fri 20/316:21
STL
-
MAN
1 stop13h 09m
Virgin Atlantic
Deal found 27/1£592
Thu 3/905:55
MAN
-
STL
2 stops19h 30m
United Airlines
Wed 9/915:30
STL
-
MAN
1 stop20h 05m
United Airlines
Deal found 27/1£593
Fri 13/306:05
MAN
-
STL
1 stop13h 50m
United Airlines
Fri 20/308:30
STL
-
MAN
2 stops20h 50m
United Airlines
Deal found 27/1£594
Thu 24/909:35
MAN
-
SGF
2 stops18h 54m
Scandinavian Airlines
Mon 28/915:30
SGF
-
MAN
2 stops35h 25m
Scandinavian Airlines
Deal found 27/1£653
Sat 14/320:15
MAN
-
MCI
3 stops32h 38m
Multiple Airlines
Sat 21/305:45
MCI
-
MAN
3 stops30h 00m
Multiple Airlines
Deal found 28/1£653
Thu 3/913:00
MAN
-
STL
1 stop13h 50m
Delta
Wed 9/911:51
STL
-
MAN
2 stops16h 09m
Delta
Deal found 28/1£686
Mon 27/407:45
MAN
-
MCI
3 stops45h 48m
Multiple Airlines
Thu 30/413:20
MCI
-
MAN
2 stops19h 10m
Multiple Airlines
Deal found 27/1£735
Fri 3/419:10
MAN
-
MCI
2 stops35h 02m
Scandinavian Airlines
Sat 25/414:10
MCI
-
MAN
2 stops22h 40m
Scandinavian Airlines
Deal found 27/1£765
Wed 4/213:30
MAN
-
MCI
1 stop14h 32m
Virgin Atlantic
Thu 19/217:06
MCI
-
MAN
1 stop11h 24m
Virgin Atlantic
Deal found 26/1£787
Tue 3/206:15
MAN
-
MCI
2 stops21h 12m
American Airlines
Thu 19/216:16
MCI
-
MAN
2 stops16h 04m
American Airlines
Deal found 26/1£792

Find flight deals from Manchester to Missouri

Keep the following information in mind while searching for Manchester to Missouri flight deals. Data was last updated 29 January 2026.

Round-trip from

£592

One-way from

£494

Popular in

August

Cheapest in

December

Average price

£764
Virgin Atlantic
  • Virgin Atlantic
  • 13/3-20/3
  • 2 total stops
  • 28h 42m total
  • Manchester to Missouri
Search Deals
Lufthansa
  • Lufthansa
  • 3/6
  • 1 total stop
  • 13h 20m total
  • Manchester to Missouri
Search Deals
Highest demand for flights based on searches. 12% potential increase in price (£85 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£14 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 January 2026.
Use the filters below to find and compare flights from Manchester to Missouri that are best for you.

Fly from

Manchester

Fly to

Missouri

Route

Depart

Return

Price

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Fri 13/3

13:25-23:58

1 stop15h 33m

Lambert-St Louis

Fri 20/3

16:21-10:30

1 stop13h 09m

£592

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Fri 13/3

06:05-14:55

1 stop13h 50m

Lambert-St Louis

Fri 20/3

08:30-10:20

2 stops20h 50m

£594

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Sat 14/3

20:15-23:53

3 stops32h 38m

Kansas City

Sat 21/3

05:45-16:45

3 stops30h 00m

£653

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Mon 27/4

07:45-23:33

3 stops45h 48m

Kansas City

Thu 30/4

13:20-14:30

2 stops19h 10m

£735

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Fri 3/4

19:10-00:12

2 stops35h 02m

Kansas City

Sat 25/4

14:10-18:50

2 stops22h 40m

£765

ManchesterSpringfield

MAN - SGF

MANSGF

Manchester

Thu 26/2

06:00-16:21

2 stops40h 21m

Springfield-Branson

Thu 5/3

11:21-08:45

2 stops15h 24m

£809

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Fri 13/3

06:05-21:59

2 stops20h 54m

Kansas City

Fri 20/3

12:34-14:50

2 stops21h 16m

£809

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Thu 26/2

09:25-23:17

2 stops19h 52m

Kansas City

Mon 2/3

09:10-08:45

2 stops17h 35m

£809

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Mon 27/4

13:00-23:50

1 stop16h 50m

Kansas City

Thu 30/4

15:04-08:50

1 stop11h 46m

£829

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Tue 3/3

11:15-21:59

2 stops16h 44m

Kansas City

Tue 24/3

12:34-10:30

2 stops16h 56m

£837

Flights are sorted by cheapest return flights first.

Deals found on 27/1

Showing 1-10 of 16 results
1
2

Best time to book a flight from Manchester to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Missouri

What is the cheapest month to book a flight from Manchester to Missouri?

Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £493). Flying from Manchester to Missouri in August is currently the most expensive (average of £772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 29 January 2026.
Get a feel of what it's like to fly with KLM, Finnair, andVirgin Atlantic from Manchester to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,443 reviews
Check prices

Comfort

7.6

Overall

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
KLM
7.7
Good
1,443 reviews
KLM
7.7
Good
1,443 reviews
Check prices

Comfort

7.6

Overall

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Finnair
7.6
Good
1,356 reviews
KLM
7.7
Good
1,443 reviews
Check prices

Comfort

7.6

Overall

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Virgin Atlantic
7.5
Good
678 reviews
KLM
7.7
Good
1,443 reviews
Check prices

Comfort

7.6

Overall

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
Aer Lingus
7.2
Good
1,442 reviews
KLM
7.7
Good
1,443 reviews
Check prices

Comfort

7.6

Overall

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.
British Airways
6.7
Okay
7,705 reviews
KLM
7.7
Good
1,443 reviews
Check prices

Comfort

7.6

Overall

7.7

Entertainment

7.1

Food

7.3

Boarding

7.8

Crew

8.4

Reviews

1 / 20
10.0
Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Missouri?

    If you book a flight to Missouri from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MAN) is located 8.9 mi from the center of Manchester.

  • How long is the flight from Manchester to Missouri?

    Airlines like Virgin Atlantic, United Airlines, and Scandinavian Airlines fly from Manchester to Missouri in about 13h 50m. The time it takes to get you to your destination can typically vary by up to 21h 12m. The distance between Manchester and Missouri is about 4061 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Manchester to Missouri?

    While some choose either Manchester - Lambert-St Louis or Manchester - Columbia Regional, Manchester - Kansas City is the most popular route from Manchester to Missouri.

  • Can I find deals for flights from Manchester to Missouri that include hotel bookings?

    Yes. In addition to deals on Manchester to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Missouri.

  • Can I find deals for business class flights from Manchester to Missouri?

    Yes. Cheapflights offers flight deals from Manchester to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Missouri?

    Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £493). Flying from Manchester to Missouri in August is currently the most expensive (average of £772). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Manchester to Missouri

Discover the top 10 airlines that operate flights from Manchester to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 29 January 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest£469Average£896FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
FinnairCheapest£502Average£633FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£550Average£789FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Scandinavian AirlinesCheapest£565Average£692FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
Virgin AtlanticCheapest£638Average£916FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£650Average£930FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£659Average£815FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Aer LingusCheapest£669Average£999FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights
LufthansaCheapest£716Average£832FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
American AirlinesCheapest£816Average£1,010FlexibilityNo cancel feeOn-time71%
Search American Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Missouri?

Deals for Manchester to Missouri flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Missouri?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Missouri from Manchester.

Can Cheapflights find flights from Manchester to Missouri with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to Missouri with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Missouri become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Missouri on Cheapflights with our Price Alert feature and get notified when better prices are available.

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