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Cheap flights from Manchester to Missouri from £295

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STL
6 Dec — 13 Dec1
1 adult
1 adult, Economy, 0 bags

Find flight deals from Manchester to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Missouri
Explore the most affordable flight options available from Manchester to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 November 2025.

Tue 2/1213:30MAN - STL
1 stop14h 27mVirgin Atlantic
Tue 9/1214:38STL - MAN
2 stops13h 32mVirgin Atlantic
Deal found 4/11£618
Wed 19/1119:15MAN - MCI
2 stops31h 55mScandinavian Airlines
Sat 22/1112:55MCI - MAN
2 stops23h 40mScandinavian Airlines
Deal found 5/11£685
Fri 5/1206:00MAN - STL
2 stops17h 08mBritish Airways
Fri 12/1214:54STL - MAN
2 stops19h 41mBritish Airways
Deal found 5/11£710
Wed 19/1106:10MAN - STL
2 stops18h 15mBritish Airways
Sat 22/1120:04STL - MAN
2 stops32h 51mBritish Airways
Deal found 5/11£750
Fri 5/1213:25MAN - STL
1 stop26h 59mDelta
Fri 12/1218:05STL - MAN
2 stops16h 00mDelta
Deal found 5/11£773
Wed 3/1206:10MAN - MCI
2 stops19h 44mMultiple Airlines
Wed 10/1217:45MCI - MAN
2 stops15h 05mMultiple Airlines
Deal found 5/11£841
Wed 3/1206:25MAN - MCI
2 stops21h 33mLufthansa
Wed 10/1212:45MCI - MAN
2 stops17h 35mLufthansa
Deal found 5/11£847
Wed 3/1206:00MAN - MCI
2 stops19h 54mUnited Airlines
Wed 10/1211:36MCI - MAN
2 stops18h 44mUnited Airlines
Deal found 5/11£849
Thu 25/1211:40MAN - STL
2 stops17h 16mMultiple Airlines
Tue 30/1216:05STL - MAN
2 stops18h 55mMultiple Airlines
Deal found 4/11£865
Tue 16/1208:05MAN - MCI
2 stops19h 24mAer Lingus
Sat 10/110:50MCI - MAN
2 stops20h 35mAer Lingus
Deal found 5/11£873
Wed 3/1213:30MAN - MCI
1 stop14h 54mVirgin Atlantic
Wed 10/1217:13MCI - MAN
1 stop11h 17mVirgin Atlantic
Deal found 5/11£889
Tue 16/1212:25MAN - MCI
2 stops15h 04mAer Lingus
Thu 8/110:50MCI - MAN
2 stops26h 25mAer Lingus
Deal found 3/11£891

Cheap flight deals from Manchester to Missouri

Keep the following information in mind while searching for Manchester to Missouri flight deals. Data was last updated 6 November 2025.

Round-trip from

£618

One-way from

£295

Popular in

August

Cheapest in

February

Average price

£887
Virgin Atlantic
  • Virgin Atlantic
  • 2/12-9/12
  • 3 total stops
  • 27h 59m total
  • Manchester to Missouri
Search Deals
10/1
  • 10/1
  • 3 total stops
  • 38h 23m total
  • Manchester to Missouri
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£75 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£14 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 6 November 2025.
Use the filters below to find and compare flights from Manchester to Missouri that are best for you.

Fly from

Manchester

Fly to

Missouri

Route

Depart

Return

Price

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Tue 2/12

13:30-21:57

1 stop14h 27m

Lambert-St Louis

Tue 9/12

14:38-10:10

2 stops13h 32m

£618

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 5/3

08:50-19:30

2 stops16h 40m

Lambert-St Louis

Mon 9/3

16:43-14:00

2 stops16h 17m

£650

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 5/3

13:30-20:41

1 stop13h 11m

Lambert-St Louis

Mon 9/3

14:18-10:10

2 stops14h 52m

£671

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 5/3

13:30-20:41

1 stop13h 11m

Lambert-St Louis

Mon 9/3

14:18-10:10

2 stops14h 52m

£673

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Wed 19/11

19:15-21:10

2 stops31h 55m

Kansas City

Sat 22/11

12:55-18:35

2 stops23h 40m

£685

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Fri 5/12

06:00-17:08

2 stops17h 08m

Lambert-St Louis

Fri 12/12

14:54-16:35

2 stops19h 41m

£710

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 19/11

06:10-18:25

2 stops18h 15m

Lambert-St Louis

Sat 22/11

20:04-10:55

2 stops32h 51m

£750

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Sat 10/1

17:35-18:34

2 stops30h 59m

Lambert-St Louis

Sat 23/5

12:09-15:45

2 stops21h 36m

£757

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Sat 10/1

13:30-11:05

1 stop27h 35m

Lambert-St Louis

Sat 23/5

15:50-14:00

2 stops16h 10m

£767

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Wed 3/12

06:10-19:54

2 stops19h 44m

Kansas City

Wed 10/12

17:45-14:50

2 stops15h 05m

£841

Flights are sorted by cheapest return flights first.

Deals found on 4/11

Showing 1-10 of 35 results
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Best time to book a flight from Manchester to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Missouri

What is the cheapest month to book a flight from Manchester to Missouri?

Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £522). Flying from Manchester to Missouri in August is currently the most expensive (average of £815). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to MO?

Find hourly flight availability from Manchester to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 6 November 2025.

A simple way to save on the total cost of your ticket is to fly from Manchester to Missouri in the afternoon. If you’re flexible enough to do this you can expect to save up to 50% on your trip compared to booking a flight at midday.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 6 November 2025.
Get a feel of what it's like to fly with KLM, Finnair, andVirgin Atlantic from Manchester to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,405 reviews
Check prices

Boarding

7.8

Entertainment

7.1

Comfort

7.7

Food

7.3

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,405 reviews
KLM
7.7
Good
1,405 reviews
Check prices

Boarding

7.8

Entertainment

7.1

Comfort

7.7

Food

7.3

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Finnair
7.6
Good
1,335 reviews
KLM
7.7
Good
1,405 reviews
Check prices

Boarding

7.8

Entertainment

7.1

Comfort

7.7

Food

7.3

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Virgin Atlantic
7.5
Good
672 reviews
KLM
7.7
Good
1,405 reviews
Check prices

Boarding

7.8

Entertainment

7.1

Comfort

7.7

Food

7.3

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Aer Lingus
7.2
Good
1,365 reviews
KLM
7.7
Good
1,405 reviews
Check prices

Boarding

7.8

Entertainment

7.1

Comfort

7.7

Food

7.3

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
British Airways
6.7
Okay
7,496 reviews
KLM
7.7
Good
1,405 reviews
Check prices

Boarding

7.8

Entertainment

7.1

Comfort

7.7

Food

7.3

Overall

7.7

Crew

8.4

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Missouri?

    If you book a flight to Missouri from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MAN) is located 8.9 mi from the center of Manchester.

  • How long is the flight from Manchester to Missouri?

    Airlines like Virgin Atlantic, American Airlines, and Scandinavian Airlines fly from Manchester to Missouri in about 14h 27m. The time it takes to get you to your destination can typically vary by up to 17h 28m. The distance between Manchester and Missouri is about 4061 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Manchester to Missouri?

    While some choose either Manchester - Lambert-St Louis or Manchester - Columbia Regional, Manchester - Kansas City is the most popular route from Manchester to Missouri.

  • Can I find deals for flights from Manchester to Missouri that include hotel bookings?

    Yes. In addition to deals on Manchester to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Missouri.

  • Can I find deals for business class flights from Manchester to Missouri?

    Yes. Cheapflights offers flight deals from Manchester to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Missouri?

    Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £522). Flying from Manchester to Missouri in August is currently the most expensive (average of £815). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Manchester to Missouri

Discover the top 10 airlines that operate flights from Manchester to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 6 November 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest£497Average£943FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
FinnairCheapest£539Average£733FlexibilityNo cancel feeOn-time76%
Search Finnair flights
Scandinavian AirlinesCheapest£598Average£730FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
British AirwaysCheapest£661Average£840FlexibilityNo cancel feeOn-time70%
Search British Airways flights
KLMCheapest£688Average£935FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£697Average£862FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Virgin AtlanticCheapest£704Average£947FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
Aer LingusCheapest£708Average£1,070FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights
LufthansaCheapest£749Average£909FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Air FranceCheapest£775Average£1,110FlexibilityNo cancel feeOn-time77%
Search Air France flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Missouri?

Deals for Manchester to Missouri flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Missouri?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Missouri from Manchester.

Can Cheapflights find flights from Manchester to Missouri with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to Missouri with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Missouri become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Missouri on Cheapflights with our Price Alert feature and get notified when better prices are available.

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