Cheap flights from Manchester to Missouri from £386

MAN — STL
6 Dec — 13 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Missouri

Tue 15/1219:15 -
2 stops32h 23m
Mon 4/112:01 -
2 stops24h 34m
Deal found 3/11£592
Thu 19/1108:10 -
2 stops21h 51m
Thu 26/1112:44 -
2 stops14h 31m
Deal found 2/11£695
Wed 2/1209:50 -
2 stops20h 46m
Wed 9/1209:11 -
2 stops18h 04m
Deal found 2/11£718
Wed 2/1210:10 -
2 stops19h 46m
Wed 9/1209:55 -
2 stops26h 40m
Deal found 2/11£734
Sat 12/1212:00 -
2 stops16h 52m
Sat 9/109:37 -
2 stops25h 08m
Deal found 2/11£768
Tue 15/1217:15 -
2 stops35h 28m
Mon 4/109:15 -
2 stops22h 20m
Deal found 5/11£786
Sun 8/1120:10 -
2 stops34h 14m
Thu 19/1106:02 -
2 stops19h 33m
Deal found 5/11£790
Mon 30/1114:15 -
2 stops35h 12m
Mon 7/1213:43 -
2 stops17h 22m
Deal found 2/11£799
Mon 21/1208:10 -
2 stops17h 42m
Sat 2/106:12 -
2 stops31h 23m
Deal found 4/11£800
Tue 22/1207:40 -
2 stops18h 12m
Tue 5/109:15 -
2 stops22h 25m
Deal found 3/11£804
Sun 8/1109:50 -
2 stops20h 34m
Fri 20/1106:02 -
2 stops28h 43m
Deal found 4/11£837
Sun 20/1220:10 -
2 stops34h 29m
Mon 4/109:22 -
2 stops29h 03m
Deal found 5/11£848

Find flight deals from Manchester to Missouri

Round-trip from

£586

One-way from

£386

Popular in

August

Cheapest in

March

Average price

£751
Scandinavian Airlines
  • Scandinavian Airlines
  • 13/1-27/1
  • 4 total stops
  • 43h 51m total
  • Manchester to Missouri
6/1-31/12
  • 6/1-31/12
  • 3 total stops
  • 57h 01m total
  • Manchester to Missouri
Highest demand for flights based on searches. 15% potential increase in price (£112 potential increase over avg. return price).
Cheapest flight prices on average. 3% potential price decrease (£21 potential savings vs. average return price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Manchester to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 12/1

06:00-22:34

2 stops22h 34m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£444

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 19/1

06:00-22:34

2 stops22h 34m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£445

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Sun 22/11

16:00-23:59

3 stops37h 59m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£488
Fastest return journey

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 19/1

12:40-23:26

1 stop16h 46m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£492

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 19/1

12:40-23:26

1 stop16h 46m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£495

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 12/1

12:40-23:26

1 stop16h 46m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£495

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 12/1

11:30-15:26

1 stop33h 56m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£497

ManchesterKansas City

MAN Manchester - MCI Kansas City

MANMCI

Manchester

Wed 30/12

19:55-17:06

3 stops51h 11m

Kansas City

Wed 31/12

00:00-07:00

Nonstop0h 00m

£514

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Sun 22/11

09:50-00:01

2 stops20h 11m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£546

ManchesterKansas City

MAN Manchester - MCI Kansas City

MANMCI

Manchester

Tue 19/1

19:15-23:56

2 stops34h 41m

Kansas City

Sat 23/1

10:14-09:30

2 stops17h 16m

£587

Flights are sorted by cheapest return flights first.

Deals found on 2/11

Showing 1-10 of 33 resultsSorted by cheapest first
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Best time to book a flight from Manchester to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Manchester with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Manchester to Missouri

What is the cheapest month to book a flight from Manchester to Missouri?

Currently, March is the cheapest month in which you can book a flight from Manchester to Missouri (average of £659). Flying from Manchester to Missouri in July is currently the most expensive (average of £1,123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Missouri?

Airfare is below average for this route at the moment.
Manchester to Missouri flights typically cost between £678 and £785 in January.
The cheapest return price found within the last 5 days was £586 on Scandinavian Airlines (13 Jan–27 Jan).

Reviews of airlines servicing Missouri

Get a feel of what it's like to fly with Scandinavian Airlines,Virgin Atlantic, andAer Lingus from Manchester to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.7

Reviews

1 / 20
6.0
Good

siavash,Oct 2026

CPH - JFK

I was seated in premium economy and I didn’t feel the crew being attentive or a warm sense of hospitality, the plane was clean. The seats were comfortable.

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.7

Reviews

1 / 20
6.0
Good

siavash,Oct 2026

CPH - JFK

I was seated in premium economy and I didn’t feel the crew being attentive or a warm sense of hospitality, the plane was clean. The seats were comfortable.

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.7

Reviews

1 / 20
6.0
Good

siavash,Oct 2026

CPH - JFK

I was seated in premium economy and I didn’t feel the crew being attentive or a warm sense of hospitality, the plane was clean. The seats were comfortable.

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.7

Reviews

1 / 20
6.0
Good

siavash,Oct 2026

CPH - JFK

I was seated in premium economy and I didn’t feel the crew being attentive or a warm sense of hospitality, the plane was clean. The seats were comfortable.

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.7

Reviews

1 / 20
6.0
Good

siavash,Oct 2026

CPH - JFK

I was seated in premium economy and I didn’t feel the crew being attentive or a warm sense of hospitality, the plane was clean. The seats were comfortable.

Comfort

7.4

Food

6.8

Crew

8.1

Entertainment

6.8

Overall

7.5

Boarding

7.7

Reviews

1 / 20
6.0
Good

siavash,Oct 2026

CPH - JFK

I was seated in premium economy and I didn’t feel the crew being attentive or a warm sense of hospitality, the plane was clean. The seats were comfortable.

Related info for your journey

  • What airport do you fly from for flights from Manchester to Missouri?

    If you book a flight to Missouri from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MAN) is located 8.9 mi from the center of Manchester.

  • How long is the flight from Manchester to Missouri?

    Airlines like Scandinavian Airlines, Aer Lingus, and Delta fly from Manchester to Missouri in about 16h 17m. The time it takes to get you to your destination can typically vary by up to 18h 24m. The distance between Manchester and Missouri is about 4061 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Manchester to Missouri?

  • Can I find deals for flights from Manchester to Missouri that include hotel bookings?

    Yes. In addition to deals on Manchester to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Missouri.

  • Can I find deals for business class flights from Manchester to Missouri?

    Yes. Cheapflights offers flight deals from Manchester to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Missouri?

    Currently, March is the cheapest month in which you can book a flight from Manchester to Missouri (average of £659). Flying from Manchester to Missouri in July is currently the most expensive (average of £1,123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Manchester to Missouri

Top 5 airlines flying from Manchester to Missouri

AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£518Average£685FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£586Average£1,009FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
Scandinavian AirlinesCheapest£598Average£799FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
LufthansaCheapest£654Average£1,005FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Aer LingusCheapest£838Average£973FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

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How does Cheapflights help users find flights from Manchester to Missouri?

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Yes! Cheapflights helps users easily find flights from Manchester to Missouri with no change fees.

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