Cheap flights from Manchester to Missouri from £394

MAN — STL
1 Dec — 8 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Missouri

Tue 15/1219:15 -
2 stops34h 50m
Mon 4/115:48 -
2 stops20h 47m
Deal found 31/10£575
Sat 12/1219:15 -
2 stops34h 50m
Wed 6/115:48 -
2 stops35h 42m
Deal found 31/10£599
Sun 20/1219:15 -
2 stops34h 41m
Sat 16/110:14 -
2 stops17h 16m
Deal found 30/10£613
Fri 18/1210:10 -
2 stops17h 28m
Mon 4/115:48 -
2 stops20h 47m
Deal found 31/10£631
Mon 14/1205:50 -
3 stops24h 22m
Mon 21/1217:58 -
3 stops32h 22m
Deal found 30/10£697
Sun 13/1219:15 -
2 stops32h 23m
Mon 4/115:48 -
2 stops20h 47m
Deal found 31/10£706
Mon 14/1212:00 -
2 stops18h 02m
Mon 21/1216:32 -
2 stops20h 13m
Deal found 30/10£738
Thu 10/1211:55 -
2 stops16h 57m
Wed 23/1206:00 -
2 stops28h 45m
Deal found 31/10£748
Tue 3/1117:15 -
2 stops35h 00m
Sat 7/1106:02 -
2 stops19h 33m
Deal found 30/10£750
Sat 12/1212:00 -
2 stops16h 52m
Sat 9/109:37 -
2 stops25h 08m
Deal found 30/10£769
Sun 8/1108:10 -
2 stops22h 14m
Fri 20/1106:02 -
2 stops28h 43m
Deal found 29/10£771
Mon 14/1220:10 -
2 stops28h 39m
Wed 30/1216:32 -
2 stops33h 03m
Deal found 1/11£778

Find flight deals from Manchester to Missouri

Round-trip from

£575

One-way from

£394

Popular in

August

Cheapest in

March

Average price

£756
Scandinavian Airlines
  • Scandinavian Airlines
  • 15/12-4/1
  • 4 total stops
  • 55h 37m total
  • Manchester to Missouri
19/1-31/12
  • 19/1-31/12
  • 3 total stops
  • 34h 20m total
  • Manchester to Missouri
Highest demand for flights based on searches. 15% potential increase in price (£113 potential increase over avg. return price).
Cheapest flight prices on average. 3% potential price decrease (£22 potential savings vs. average return price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Manchester to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 19/1

06:00-10:20

3 stops34h 20m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£394

ManchesterKansas City

MAN Manchester - MCI Kansas City

MANMCI

Manchester

Wed 23/12

08:10-18:08

3 stops39h 58m

Kansas City

Wed 31/12

00:00-07:00

Nonstop0h 00m

£454

ManchesterKansas City

MAN Manchester - MCI Kansas City

MANMCI

Manchester

Tue 22/12

06:00-19:56

3 stops43h 56m

Kansas City

Wed 31/12

00:00-07:00

Nonstop0h 00m

£455

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Sat 7/11

09:50-23:16

3 stops43h 26m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£463

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 19/1

12:40-23:26

1 stop16h 46m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£495

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Tue 19/1

10:55-23:26

2 stops18h 31m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£495

ManchesterKansas City

MAN Manchester - MCI Kansas City

MANMCI

Manchester

Sun 27/12

20:45-19:56

3 stops53h 11m

Kansas City

Wed 31/12

00:00-07:00

Nonstop0h 00m

£520

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Sat 7/11

08:10-18:17

2 stops16h 07m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£564

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Fri 6/11

08:10-18:17

2 stops16h 07m

Lambert-St Louis

Wed 31/12

00:00-07:00

Nonstop0h 00m

£564

ManchesterSt. Louis

MAN Manchester - STL Lambert-St Louis

MANSTL

Manchester

Thu 21/1

10:10-23:26

2 stops19h 16m

Lambert-St Louis

Mon 25/1

10:13-09:30

2 stops41h 17m

£595

Flights are sorted by cheapest return flights first.

Deals found on 28/10

Showing 1-10 of 34 resultsSorted by cheapest first
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Best time to book a flight from Manchester to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Manchester with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Manchester to Missouri

What is the cheapest month to book a flight from Manchester to Missouri?

Currently, March is the cheapest month in which you can book a flight from Manchester to Missouri (average of £663). Flying from Manchester to Missouri in July is currently the most expensive (average of £1,130). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Missouri?

Airfare is below average for this route at the moment.
Manchester to Missouri flights typically cost between £682 and £789 in December.
The cheapest return price found within the last 5 days was £575 on Scandinavian Airlines (15 Dec–4 Jan).

Reviews of airlines servicing Missouri

Get a feel of what it's like to fly with Virgin Atlantic,Scandinavian Airlines, andAer Lingus from Manchester to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.7

Food

6.9

Comfort

7.3

Crew

8.1

Entertainment

7.5

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Boarding

7.7

Food

6.9

Comfort

7.3

Crew

8.1

Entertainment

7.5

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Boarding

7.7

Food

6.9

Comfort

7.3

Crew

8.1

Entertainment

7.5

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Boarding

7.7

Food

6.9

Comfort

7.3

Crew

8.1

Entertainment

7.5

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Boarding

7.7

Food

6.9

Comfort

7.3

Crew

8.1

Entertainment

7.5

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Boarding

7.7

Food

6.9

Comfort

7.3

Crew

8.1

Entertainment

7.5

Overall

7.5

Reviews

1 / 20
10.0
Excellent

Edwin,May 2026

LHR - LAX

First time flying with Virgin. It was everything I hoped it would be.

Related info for your journey

  • What airport do you fly from for flights from Manchester to Missouri?

    If you book a flight to Missouri from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MAN) is located 8.9 mi from the center of Manchester.

  • How long is the flight from Manchester to Missouri?

    Airlines like Scandinavian Airlines, Aer Lingus, and Delta fly from Manchester to Missouri in about 16h 57m. The time it takes to get you to your destination can typically vary by up to 3h 26m. The distance between Manchester and Missouri is about 4195 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Manchester to Missouri?

  • Can I find deals for flights from Manchester to Missouri that include hotel bookings?

    Yes. In addition to deals on Manchester to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Missouri.

  • Can I find deals for business class flights from Manchester to Missouri?

    Yes. Cheapflights offers flight deals from Manchester to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Missouri?

    Currently, March is the cheapest month in which you can book a flight from Manchester to Missouri (average of £663). Flying from Manchester to Missouri in July is currently the most expensive (average of £1,130). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Manchester to Missouri

Top 5 airlines flying from Manchester to Missouri

AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£521Average£689FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£590Average£1,016FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
Scandinavian AirlinesCheapest£602Average£804FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
LufthansaCheapest£658Average£1,012FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Aer LingusCheapest£843Average£979FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

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Yes! Cheapflights helps users easily find flights from Manchester to Missouri with no change fees.

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