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Cheap flights from Manchester to Missouri from £296

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STL
10 Apr — 17 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Missouri
Explore the most affordable flight options available from Manchester to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 March 2026.

Fri 11/912:15
MAN
-
STL
1 stop13h 15m
British Airways
Mon 14/916:47
STL
-
MAN
2 stops14h 23m
British Airways
Deal found 5/3£653
Thu 23/420:00
MAN
-
STL
1 stop29h 30m
British Airways
Thu 30/408:54
STL
-
MAN
2 stops18h 51m
British Airways
Deal found 9/3£676
Sun 19/420:00
MAN
-
STL
2 stops27h 21m
British Airways
Sun 26/408:54
STL
-
MAN
2 stops19h 01m
British Airways
Deal found 6/3£682
Thu 3/906:55
MAN
-
STL
2 stops18h 28m
British Airways
Wed 9/912:47
STL
-
MAN
2 stops15h 03m
British Airways
Deal found 6/3£687
Sun 19/411:15
MAN
-
STL
1 stop12h 29m
Virgin Atlantic
Sun 26/418:50
STL
-
MAN
1 stop32h 00m
Virgin Atlantic
Deal found 6/3£692
Mon 20/410:35
MAN
-
MCI
3 stops39h 10m
United Airlines
Mon 27/412:40
MCI
-
MAN
2 stops15h 10m
United Airlines
Deal found 6/3£888
Wed 22/410:35
MAN
-
MCI
2 stops28h 17m
United Airlines
Wed 29/412:40
MCI
-
MAN
2 stops15h 10m
United Airlines
Deal found 8/3£893
Wed 8/410:35
MAN
-
MCI
2 stops17h 24m
Lufthansa
Wed 22/411:30
MCI
-
MAN
2 stops16h 55m
Lufthansa
Deal found 10/3£909
Thu 12/1106:10
MAN
-
SGF
2 stops24h 47m
United Airlines
Mon 16/1111:22
SGF
-
MAN
2 stops23h 38m
United Airlines
Deal found 9/3£922
Thu 19/1106:10
MAN
-
COU
2 stops21h 10m
United Airlines
Mon 23/1105:00
COU
-
MAN
2 stops23h 20m
United Airlines
Deal found 9/3£922
Fri 2/1005:55
MAN
-
MCI
2 stops34h 57m
United Airlines
Tue 6/1008:05
MCI
-
MAN
2 stops19h 45m
United Airlines
Deal found 9/3£928
Thu 17/905:55
MAN
-
MCI
2 stops39h 09m
United Airlines
Mon 21/915:14
MCI
-
MAN
2 stops19h 56m
United Airlines
Deal found 5/3£929

Find flight deals from Manchester to Missouri

Keep the following information in mind while searching for Manchester to Missouri flight deals. Data was last updated 11 March 2026.

Round-trip from

£676

One-way from

£296

Popular in

August

Cheapest in

December

Average price

£779
British Airways
  • British Airways
  • 23/4-30/4
  • 3 total stops
  • 48h 21m total
  • Manchester to Missouri
Search Deals
22/4
  • 22/4
  • 3 total stops
  • 45h 49m total
  • Manchester to Missouri
Search Deals
Highest demand for flights based on searches. 12% potential increase in price (£87 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 March 2026.
Use the filters below to find and compare flights from Manchester to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 3/9

10:50-23:42

2 stops18h 52m

Lambert-St Louis

Wed 9/9

16:47-15:30

2 stops16h 43m

£687

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 6/5

07:05-22:17

2 stops21h 12m

Lambert-St Louis

Sun 10/5

20:03-22:35

2 stops20h 32m

£696

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Mon 20/4

10:35-19:45

3 stops39h 10m

Kansas City

Mon 27/4

12:40-09:50

2 stops15h 10m

£888

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Wed 22/4

10:35-08:52

2 stops28h 17m

Kansas City

Wed 29/4

12:40-09:50

2 stops15h 10m

£893

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Fri 24/4

10:35-19:45

3 stops39h 10m

Kansas City

Fri 1/5

12:50-09:50

2 stops15h 00m

£949

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Tue 28/4

10:35-10:27

2 stops29h 52m

Kansas City

Wed 24/6

12:30-10:25

2 stops15h 55m

£953

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Mon 27/4

06:00-22:29

3 stops22h 29m

Kansas City

Tue 23/6

12:30-10:25

2 stops15h 55m

£954

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Fri 31/7

13:00-09:40

1 stop26h 40m

Lambert-St Louis

Tue 15/12

09:00-06:40

2 stops15h 40m

£955
Fastest return journey

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Sat 1/8

13:15-23:38

1 stop16h 23m

Lambert-St Louis

Wed 16/12

13:30-10:30

1 stop15h 00m

£955

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 23/4

10:35-23:57

2 stops19h 22m

Lambert-St Louis

Thu 30/4

20:30-09:50

2 stops31h 20m

£963

Flights are sorted by cheapest return flights first.

Deals found on 10/3

Showing 1-10 of 38 resultsSorted by cheapest first
1
2
3
4

Best time to book a flight from Manchester to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Missouri

What is the cheapest month to book a flight from Manchester to Missouri?

Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £498). Flying from Manchester to Missouri in August is currently the most expensive (average of £775). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 11 March 2026.
Get a feel of what it's like to fly with KLM,Virgin Atlantic, andUnited Airlines from Manchester to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,468 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Overall

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,468 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Overall

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Virgin Atlantic
7.5
Good
680 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Overall

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,413 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Overall

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Aer Lingus
7.2
Good
1,473 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Overall

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6.7
Okay
7,781 reviews
KLM
7.8
Good
1,468 reviews
Check prices

Entertainment

7.1

Boarding

7.8

Overall

7.8

Comfort

7.6

Crew

8.4

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Manchester to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Missouri?

    If you book a flight to Missouri from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MAN) is located 8.9 mi from the center of Manchester.

  • How long is the flight from Manchester to Missouri?

    Airlines like British Airways, United Airlines, and Delta fly from Manchester to Missouri in about 18h 52m. The time it takes to get you to your destination can typically vary by up to 20h 18m. The distance between Manchester and Missouri is about 4061 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Manchester to Missouri?

    While some choose either Manchester - Lambert-St Louis or Manchester - Columbia Regional, Manchester - Kansas City is the most popular route from Manchester to Missouri.

  • Can I find deals for flights from Manchester to Missouri that include hotel bookings?

    Yes. In addition to deals on Manchester to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Missouri.

  • Can I find deals for business class flights from Manchester to Missouri?

    Yes. Cheapflights offers flight deals from Manchester to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Missouri?

    Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £498). Flying from Manchester to Missouri in August is currently the most expensive (average of £775). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Manchester to Missouri

Discover the top 9 airlines that operate flights from Manchester to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 11 March 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£553Average£820FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Scandinavian AirlinesCheapest£580Average£709FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
DeltaCheapest£606Average£857FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Virgin AtlanticCheapest£655Average£941FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£667Average£1,001FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£676Average£832FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£720Average£896FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
American AirlinesCheapest£838Average£1,036FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
Aer LingusCheapest£841Average£998FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Missouri?

Deals for Manchester to Missouri flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Missouri?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Missouri from Manchester.

Can Cheapflights find flights from Manchester to Missouri with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to Missouri with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Missouri become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Missouri on Cheapflights with our Price Alert feature and get notified when better prices are available.

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