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Cheap flights from Manchester to Missouri from £570

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/7. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STL
17 May — 24 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Missouri
Explore the most affordable flight options available from Manchester to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 April 2026.

Tue 15/912:20
MAN
-
STL
2 stops17h 00m
British Airways
Wed 23/909:46
STL
-
MAN
2 stops18h 04m
British Airways
Deal found 17/4£688
Wed 28/1009:50
MAN
-
STL
2 stops18h 51m
British Airways
Wed 9/1211:50
STL
-
MAN
2 stops15h 10m
British Airways
Deal found 14/4£697
Wed 28/1009:50
MAN
-
STL
2 stops18h 35m
Multiple Airlines
Wed 9/1216:15
STL
-
MAN
1 stop10h 45m
Multiple Airlines
Deal found 14/4£706
Tue 15/915:00
MAN
-
STL
1 stop31h 55m
Multiple Airlines
Wed 23/909:46
STL
-
MAN
2 stops18h 04m
Multiple Airlines
Deal found 17/4£722
Tue 15/913:00
MAN
-
STL
1 stop16h 37m
Virgin Atlantic
Wed 23/913:30
STL
-
MAN
1 stop11h 45m
Virgin Atlantic
Deal found 17/4£727
Wed 2/1208:55
MAN
-
STL
2 stops18h 57m
British Airways
Sun 6/1218:13
STL
-
MAN
2 stops15h 22m
British Airways
Deal found 12/4£737
Thu 3/910:50
MAN
-
STL
2 stops17h 35m
British Airways
Wed 9/909:46
STL
-
MAN
2 stops18h 04m
British Airways
Deal found 13/4£746
Wed 13/507:55
MAN
-
MCI
3 stops31h 34m
Multiple Airlines
Wed 20/510:35
MCI
-
MAN
3 stops31h 10m
Multiple Airlines
Deal found 15/4£855
Wed 2/1210:10
MAN
-
SGF
2 stops18h 22m
Scandinavian Airlines
Sun 6/1206:00
SGF
-
MAN
2 stops45h 30m
Scandinavian Airlines
Deal found 16/4£868
Mon 11/513:00
MAN
-
MCI
1 stop15h 23m
Virgin Atlantic
Mon 18/508:05
MCI
-
MAN
2 stops18h 10m
Virgin Atlantic
Deal found 13/4£874
Wed 2/1208:55
MAN
-
SGF
2 stops18h 39m
British Airways
Sun 6/1215:57
SGF
-
MAN
2 stops17h 38m
British Airways
Deal found 12/4£889
Wed 29/412:10
MAN
-
MCI
2 stops16h 01m
Virgin Atlantic
Wed 6/512:25
MCI
-
MAN
1 stop12h 50m
Virgin Atlantic
Deal found 15/4£895

Find flight deals from Manchester to Missouri

Keep the following information in mind while searching for Manchester to Missouri flight deals. Data was last updated 17 April 2026.

Round-trip from

£688

One-way from

£570

Popular in

July

Cheapest in

March

Average price

£844
British Airways
  • British Airways
  • 15/9-23/9
  • 4 total stops
  • 35h 04m total
  • Manchester to Missouri
Search Deals
22/7
  • 22/7
  • 3 total stops
  • 21h 58m total
  • Manchester to Missouri
Search Deals
Highest demand for flights based on searches. 17% potential increase in price (£135 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£18 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 April 2026.
Use the filters below to find and compare flights from Manchester to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Tue 15/9

15:00-16:55

1 stop31h 55m

Lambert-St Louis

Wed 23/9

09:46-09:50

2 stops18h 04m

£722

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 3/9

10:50-22:25

2 stops17h 35m

Lambert-St Louis

Wed 9/9

09:46-09:50

2 stops18h 04m

£746

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 3/9

08:50-19:14

2 stops16h 24m

Lambert-St Louis

Wed 9/9

21:35-21:45

1 stop18h 10m

£755

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 3/9

13:00-20:50

1 stop13h 50m

Lambert-St Louis

Wed 9/9

17:45-16:55

2 stops17h 10m

£779

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Thu 28/5

19:55-13:25

2 stops23h 30m

Lambert-St Louis

Thu 4/6

14:15-14:40

3 stops18h 25m

£839

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 27/5

13:50-19:30

1 stop11h 40m

Lambert-St Louis

Wed 3/6

19:51-21:45

2 stops19h 54m

£852

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Mon 11/5

13:00-22:23

1 stop15h 23m

Kansas City

Mon 18/5

08:05-08:15

2 stops18h 10m

£874

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Sun 31/5

20:45-20:52

2 stops30h 07m

Kansas City

Sun 7/6

17:40-08:50

1 stop33h 10m

£909

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Wed 13/5

08:55-23:49

2 stops20h 54m

Kansas City

Wed 20/5

10:32-08:15

2 stops15h 43m

£910

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Wed 29/4

10:40-23:50

1 stop19h 10m

Kansas City

Wed 6/5

12:17-08:25

2 stops14h 08m

£915

Flights are sorted by cheapest return flights first.

Deals found on 13/4

Showing 1-10 of 30 resultsSorted by cheapest first
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2
3

Best time to book a flight from Manchester to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Missouri

What is the cheapest month to book a flight from Manchester to Missouri?

Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £384). Flying from Manchester to Missouri in April is currently the most expensive (average of £737). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 17 April 2026.
Get a feel of what it's like to fly with KLM,Virgin Atlantic, andUnited Airlines from Manchester to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,499 reviews
Check prices

Food

7.3

Crew

8.4

Overall

7.8

Comfort

7.7

Boarding

7.8

Entertainment

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.8
Good
1,499 reviews
KLM
7.8
Good
1,499 reviews
Check prices

Food

7.3

Crew

8.4

Overall

7.8

Comfort

7.7

Boarding

7.8

Entertainment

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Virgin Atlantic
7.5
Good
687 reviews
KLM
7.8
Good
1,499 reviews
Check prices

Food

7.3

Crew

8.4

Overall

7.8

Comfort

7.7

Boarding

7.8

Entertainment

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,602 reviews
KLM
7.8
Good
1,499 reviews
Check prices

Food

7.3

Crew

8.4

Overall

7.8

Comfort

7.7

Boarding

7.8

Entertainment

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Aer Lingus
7.3
Good
1,512 reviews
KLM
7.8
Good
1,499 reviews
Check prices

Food

7.3

Crew

8.4

Overall

7.8

Comfort

7.7

Boarding

7.8

Entertainment

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6.7
Okay
7,889 reviews
KLM
7.8
Good
1,499 reviews
Check prices

Food

7.3

Crew

8.4

Overall

7.8

Comfort

7.7

Boarding

7.8

Entertainment

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Manchester to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Missouri?

    If you book a flight to Missouri from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MAN) is located 8.9 mi from the center of Manchester.

  • How long is the flight from Manchester to Missouri?

    Airlines like British Airways, Virgin Atlantic, and Delta fly from Manchester to Missouri in about 15h 23m. The time it takes to get you to your destination can typically vary by up to 5h 31m. The distance between Manchester and Missouri is about 4195 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Manchester to Missouri?

    While some choose either Manchester - Lambert-St Louis or Manchester - Columbia Regional, Manchester - Kansas City is the most popular route from Manchester to Missouri.

  • Can I find deals for flights from Manchester to Missouri that include hotel bookings?

    Yes. In addition to deals on Manchester to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Missouri.

  • Can I find deals for business class flights from Manchester to Missouri?

    Yes. Cheapflights offers flight deals from Manchester to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Missouri?

    Currently, January is the cheapest month in which you can book a flight from Manchester to Missouri (average of £384). Flying from Manchester to Missouri in April is currently the most expensive (average of £737). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Manchester to Missouri

Discover the top 8 airlines that operate flights from Manchester to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 17 April 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£548Average£810FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£564Average£940FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
DeltaCheapest£602Average£850FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Scandinavian AirlinesCheapest£617Average£768FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
KLMCheapest£662Average£994FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£671Average£825FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£695Average£1,000FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Aer LingusCheapest£835Average£963FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Missouri?

Deals for Manchester to Missouri flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Missouri?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Missouri from Manchester.

Can Cheapflights find flights from Manchester to Missouri with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to Missouri with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Missouri become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Missouri on Cheapflights with our Price Alert feature and get notified when better prices are available.

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