Find flights
When to book
Airlines
FAQs

Cheap flights from Manchester to Missouri from £359

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — STL
21 Mar — 28 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to Missouri
Explore the most affordable flight options available from Manchester to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 19 February 2026.

Fri 13/318:55
MAN
-
MCI
3 stops33h 58m
Multiple Airlines
Fri 20/305:45
MCI
-
MAN
3 stops32h 50m
Multiple Airlines
Deal found 18/2£565
Tue 17/309:50
MAN
-
MCI
2 stops19h 03m
Multiple Airlines
Tue 24/305:45
MCI
-
MAN
2 stops25h 10m
Multiple Airlines
Deal found 15/2£637
Wed 4/313:30
MAN
-
STL
1 stop16h 06m
Virgin Atlantic
Wed 29/411:42
STL
-
MAN
1 stop13h 33m
Virgin Atlantic
Deal found 16/2£656
Thu 3/910:05
MAN
-
STL
2 stops19h 46m
Finnair
Wed 9/912:47
STL
-
MAN
2 stops15h 03m
Finnair
Deal found 16/2£657
Wed 4/307:50
MAN
-
STL
2 stops19h 22m
British Airways
Wed 29/414:33
STL
-
MAN
2 stops13h 17m
British Airways
Deal found 16/2£664
Thu 3/906:55
MAN
-
STL
2 stops18h 28m
British Airways
Wed 9/921:35
STL
-
MAN
1 stop11h 55m
British Airways
Deal found 18/2£672
Tue 7/408:35
MAN
-
STL
2 stops19h 44m
British Airways
Tue 28/417:21
STL
-
MAN
2 stops15h 49m
British Airways
Deal found 18/2£675
Fri 13/313:25
MAN
-
STL
1 stop15h 33m
Virgin Atlantic
Tue 17/312:04
STL
-
MAN
1 stop17h 26m
Virgin Atlantic
Deal found 17/2£680
Fri 13/318:55
MAN
-
MCI
3 stops33h 58m
Multiple Airlines
Tue 17/305:45
MCI
-
MAN
3 stops26h 30m
Multiple Airlines
Deal found 17/2£687
Fri 13/310:10
MAN
-
STL
3 stops34h 19m
Multiple Airlines
Tue 17/316:05
STL
-
MAN
3 stops21h 30m
Multiple Airlines
Deal found 17/2£688
Thu 3/913:00
MAN
-
STL
1 stop25h 06m
Delta
Wed 9/917:45
STL
-
MAN
2 stops14h 15m
Delta
Deal found 16/2£695
Fri 13/310:15
MAN
-
STL
2 stops15h 56m
British Airways
Tue 17/316:13
STL
-
MAN
2 stops16h 47m
British Airways
Deal found 17/2£698

Find flight deals from Manchester to Missouri

Keep the following information in mind while searching for Manchester to Missouri flight deals. Data was last updated 19 February 2026.

Round-trip from

£565

One-way from

£492

Popular in

August

Cheapest in

December

Average price

£777
13/3-20/3
  • 13/3-20/3
  • 6 total stops
  • 66h 48m total
  • Manchester to Missouri
Search Deals
7/7
  • 7/7
  • 3 total stops
  • 46h 20m total
  • Manchester to Missouri
Search Deals
Highest demand for flights based on searches. 12% potential increase in price (£87 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£16 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 19 February 2026.
Use the filters below to find and compare flights from Manchester to Missouri that are best for you.

Fly from

Manchester

Fly to

Missouri

Route

Depart

Return

Price

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Fri 13/3

18:55-23:53

3 stops33h 58m

Kansas City

Fri 20/3

05:45-19:35

3 stops32h 50m

£565

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Tue 17/3

09:50-23:53

2 stops19h 03m

Kansas City

Tue 24/3

05:45-11:55

2 stops25h 10m

£637

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 4/3

13:30-23:36

1 stop16h 06m

Lambert-St Louis

Wed 29/4

11:42-07:15

1 stop13h 33m

£656

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 4/3

07:50-21:12

2 stops19h 22m

Lambert-St Louis

Wed 29/4

14:33-09:50

2 stops13h 17m

£664

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Tue 7/4

07:55-22:19

2 stops20h 24m

Lambert-St Louis

Tue 28/4

21:35-15:10

1 stop11h 35m

£675

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Fri 13/3

13:25-23:58

1 stop15h 33m

Lambert-St Louis

Tue 17/3

12:04-10:30

1 stop17h 26m

£680

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Fri 13/3

10:15-21:11

2 stops15h 56m

Lambert-St Louis

Tue 17/3

16:13-14:00

2 stops16h 47m

£698

ManchesterKansas City

MAN - MCI

MANMCI

Manchester

Fri 27/3

19:15-00:12

2 stops33h 57m

Kansas City

Sat 18/4

14:10-08:55

2 stops36h 45m

£726

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Wed 1/4

06:05-13:25

1 stop13h 20m

Lambert-St Louis

Wed 8/4

15:30-00:50

2 stops27h 20m

£794

ManchesterSt. Louis

MAN - STL

MANSTL

Manchester

Fri 12/6

20:50-15:58

2 stops25h 08m

Lambert-St Louis

Sat 20/6

15:42-08:15

2 stops58h 33m

£798

Flights are sorted by cheapest return flights first.

Deals found on 18/2

Showing 1-10 of 35 results
1
2
3
4

Best time to book a flight from Manchester to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Missouri

What is the cheapest month to book a flight from Manchester to Missouri?

Currently, May is the cheapest month in which you can book a flight from Manchester to Missouri (average of £291). Flying from Manchester to Missouri in August is currently the most expensive (average of £771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 19 February 2026.
Get a feel of what it's like to fly with KLM, Virgin Atlantic, andUnited Airlines from Manchester to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,459 reviews
Check prices

Food

7.3

Overall

7.7

Boarding

7.8

Crew

8.4

Comfort

7.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
KLM
7.7
Good
1,459 reviews
KLM
7.7
Good
1,459 reviews
Check prices

Food

7.3

Overall

7.7

Boarding

7.8

Crew

8.4

Comfort

7.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Virgin Atlantic
7.5
Good
679 reviews
KLM
7.7
Good
1,459 reviews
Check prices

Food

7.3

Overall

7.7

Boarding

7.8

Crew

8.4

Comfort

7.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
United Airlines
7.4
Good
9,323 reviews
KLM
7.7
Good
1,459 reviews
Check prices

Food

7.3

Overall

7.7

Boarding

7.8

Crew

8.4

Comfort

7.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
Aer Lingus
7.2
Good
1,455 reviews
KLM
7.7
Good
1,459 reviews
Check prices

Food

7.3

Overall

7.7

Boarding

7.8

Crew

8.4

Comfort

7.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas
British Airways
6.7
Okay
7,752 reviews
KLM
7.7
Good
1,459 reviews
Check prices

Food

7.3

Overall

7.7

Boarding

7.8

Crew

8.4

Comfort

7.6

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2026

EZE - SCL

It was a short trip The aeroplane was delay I arrived in Chile late and I lost my fly with Qantas

Related info for your journey

Find useful and relevant information for your journey from Manchester to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to Missouri?

    If you book a flight to Missouri from Manchester, you will be flying from Manchester, which is the city’s only airport. Manchester (MAN) is located 8.9 mi from the center of Manchester.

  • How long is the flight from Manchester to Missouri?

    Airlines like Virgin Atlantic, British Airways, and Scandinavian Airlines fly from Manchester to Missouri in about 16h 06m. The time it takes to get you to your destination can typically vary by up to 17h 51m. The distance between Manchester and Missouri is about 4061 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from Manchester to Missouri?

    While some choose either Manchester - Springfield-Branson or Manchester - Lambert-St Louis, Manchester - Kansas City is the most popular route from Manchester to Missouri.

  • Can I find deals for flights from Manchester to Missouri that include hotel bookings?

    Yes. In addition to deals on Manchester to Missouri flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Missouri.

  • Can I find deals for business class flights from Manchester to Missouri?

    Yes. Cheapflights offers flight deals from Manchester to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to Missouri?

    Currently, May is the cheapest month in which you can book a flight from Manchester to Missouri (average of £291). Flying from Manchester to Missouri in August is currently the most expensive (average of £771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to John F Kennedy Intl flights
Heathrow to Newark flights
Heathrow to LaGuardia flights
Gatwick to Newark flights
Heathrow to Dallas/Fort Worth flights
London City to John F Kennedy Intl flights
Heathrow to Orlando flights
Heathrow to Miami flights
Gatwick to John F Kennedy Intl flights
Stansted to John F Kennedy Intl flights
Heathrow to Los Angeles flights
Gatwick to LaGuardia flights
London City to Newark flights
Heathrow to Boston flights
Luton to John F Kennedy Intl flights
Manchester to Orlando flights
Heathrow to San Francisco flights
Gatwick to Orlando flights
Manchester to John F Kennedy Intl flights
Gatwick to Dallas/Fort Worth flights
Luton to Newark flights
Heathrow to Las Vegas flights
Stansted to Newark flights
Heathrow to Seattle flights
Heathrow to O'Hare Intl flights
Gatwick to Miami flights
Heathrow to Dulles Intl flights
Gatwick to Boston flights
Heathrow to Hobby flights
London City to Dallas/Fort Worth flights
Stansted to Dallas/Fort Worth flights
Edinburgh to John F Kennedy Intl flights
Edinburgh to Newark flights
London City to Miami flights
Heathrow to Atlanta flights
Stansted to Miami flights
Gatwick to Los Angeles flights
Heathrow to Tampa flights
Stansted to Orlando flights
Stansted to Los Angeles flights
Heathrow to George Bush Intcntl flights
Heathrow to Love Field flights
Luton to Dallas/Fort Worth flights
Heathrow to Baltimore flights
London City to Los Angeles flights
Manchester to Newark flights
London City to Boston flights
Manchester to LaGuardia flights
London City to Orlando flights
Luton to Miami flights

Top 10 airlines flying from Manchester to Missouri

Discover the top 10 airlines that operate flights from Manchester to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 19 February 2026.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£515Average£611FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£549Average£823FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Scandinavian AirlinesCheapest£576Average£704FlexibilityNo cancel feeOn-time77%
Search Scandinavian Airlines flights
DeltaCheapest£602Average£837FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Virgin AtlanticCheapest£650Average£934FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£662Average£978FlexibilityNo cancel feeOn-time75%
Search KLM flights
United AirlinesCheapest£671Average£828FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
Aer LingusCheapest£681Average£1,035FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights
LufthansaCheapest£715Average£889FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
American AirlinesCheapest£831Average£1,028FlexibilityNo cancel feeOn-time71%
Search American Airlines flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to Missouri?

Deals for Manchester to Missouri flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to Missouri?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Missouri from Manchester.

Can Cheapflights find flights from Manchester to Missouri with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to Missouri with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to Missouri become cheaper?

Not ready to book yet? You can track prices for flights from Manchester to Missouri on Cheapflights with our Price Alert feature and get notified when better prices are available.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.