Cheap flights from Panama City to Brussels Bruxelles-National Airport from £387

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — BRU
4 Aug — 11 Aug1
1 adult

Cheap flight deals from Panama City to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 July 2025.

Round-trip from

£593

One-way from

£387

Popular in

July

Cheapest in

January

Average price

£717
Turkish Airlines
  • Turkish Airlines
  • 17/9-1/10
  • 2 total stops
  • 54h 05m total
  • Panama City to Brussels
Turkish Airlines
  • Turkish Airlines
  • 10/8
  • 1 total stop
  • 29h 15m total
  • Panama City to Brussels
Highest demand for flights based on searches. 7% potential increase in price (£37 potential increase over avg. return price).
Cheapest flight prices on average. 1% potential price decrease (£5 potential savings vs. average return price).
Average for round-trip flights in July 2025

Find flight deals from Panama City to Bruxelles-National

Cheapest flights from Panama City to Bruxelles-National
Explore the most affordable flight options available from Panama City to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 July 2025.

Wed 17/921:55PTY - BRU
1 stop34h 20mTurkish Airlines
Wed 1/1007:15BRU - PTY
1 stop19h 45mTurkish Airlines
Deal found 28/7£593
Thu 27/1118:45PTY - BRU
1 stop13h 30mKLM
Sat 3/106:15BRU - PTY
1 stop16h 15mKLM
Deal found 28/7£659
Tue 19/820:25PTY - BRU
1 stop30h 20mAir Europa
Tue 26/810:45BRU - PTY
1 stop14h 55mAir Europa
Deal found 29/7£731
Thu 11/909:45PTY - BRU
1 stop14h 15mUnited Airlines
Thu 18/912:00BRU - PTY
2 stops32h 50mUnited Airlines
Deal found 28/7£793
Tue 21/1003:20PTY - BRU
2 stops28h 00mMultiple Airlines
Wed 29/1021:55BRU - PTY
2 stops33h 05mMultiple Airlines
Deal found 28/7£985

Cheapflights Fare Finder

 
Customise your flight search to find flights from Panama City to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 July 2025.
Use the filters below to find and compare flights from Panama City to Brussels Bruxelles-National Airport that are best for you.

Fly from

Panama City

Fly to

Bruxelles-National

Route

Depart

Return

Price

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Wed 17/9

21:55-15:15

1 stop34h 20m

Brussels Bruxelles-National

Wed 1/10

07:15-20:00

1 stop19h 45m

£593

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Thu 27/11

18:45-14:15

1 stop13h 30m

Brussels Bruxelles-National

Sat 3/1

06:15-16:30

1 stop16h 15m

£659

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 19/8

20:25-09:45

1 stop30h 20m

Brussels Bruxelles-National

Tue 26/8

10:45-18:40

1 stop14h 55m

£731

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Thu 11/9

09:45-07:00

1 stop14h 15m

Brussels Bruxelles-National

Thu 18/9

12:00-13:50

2 stops32h 50m

£793

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Tue 21/10

03:20-14:20

2 stops28h 00m

Brussels Bruxelles-National

Wed 29/10

21:55-01:00

2 stops33h 05m

£985

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 10/8

21:55-10:10

1 stop29h 15m

£387

Panama CityBrussels

PTY - BRU

PTYBRU

Panama City Tocumen Intl

Sun 31/8

22:29-08:05

2 stops26h 36m

£761

Flights are sorted by cheapest return flights first.

Deals found on 28/7

Best time to book a flight from Panama City to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Brussels Bruxelles-National Airport

How far ahead should I book a flight from Panama City to Brussels Bruxelles-National Airport?

Use this chart to determine the optimal time to book a return flight from Panama City to Bruxelles-National. Price data was last updated on 25 July 2025.

To ensure you get the cheapest price possible for a flight from Panama City to Brussels Bruxelles-National Airport, you should look to book at least 62 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

Currently, January is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of £117). Flying from Panama City to Brussels Bruxelles-National Airport in July is currently the most expensive (average of £168). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated 30 July 2025.
Read through reviews of airlines operating flights from Panama City to Brussels Bruxelles-National Airport, such as KLM, United Airlines, andTurkish Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Panama City to Brussels Bruxelles-National?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly out of when you book flights from Panama City to Brussels Bruxelles-National. 0 airlines have flights from Tocumen Intl to Brussels Bruxelles-National on a regular basis. Booking flights from Panama City Tocumen Intl to Brussels Bruxelles-National should not be difficult; the airport handles an average of 0 outbound flights to Brussels Bruxelles-National per day.

  • What are the cheapest airlines flying from Panama City to Brussels Bruxelles-National Airport round-trip?

    Flying on Turkish Airlines is currently your cheapest option to Brussels Bruxelles-National Airport, with prices starting at £593. Additional return tickets that might be worth considering are offered by KLM and Air Europa, with the lowest prices starting at £659 and £731, respectively. You may be able to fly from Panama City to Brussels Bruxelles-National Airport for 8% less than the average price by searching for these airlines.

  • Can I find deals for flights from Panama City to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Panama City to Bruxelles-National flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Bruxelles-National.

  • Can I find deals for business class flights from Panama City to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Panama City to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Brussels Bruxelles-National Airport?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Brussels Bruxelles-National Airport (average of £117). Flying from Panama City to Brussels Bruxelles-National Airport in July is currently the most expensive (average of £168). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Ypres
Leuven
Mons
Hasselt
Spa
Charleroi
Mechelen
Zaventem

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City to Bruxelles-National?

Deals for Panama City to Bruxelles-National flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Bruxelles-National?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City to Bruxelles-National for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City to Bruxelles-National with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Panama City to Bruxelles-National flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Panama City to Bruxelles-National become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Bruxelles-National from Panama City today and book when prices fit your budget.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.