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Cheap flights from Brussels Bruxelles-National Airport to Panama City from £477

BRU — PTY
2 Oct — 9 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Bruxelles-National to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Bruxelles-National to Panama City

Sun 1/1118:55 -
1 stop30h 50m
Thu 12/1121:30 -
1 stop14h 15m
Deal found 1/9£547
Thu 24/906:20 -
2 stops20h 11m
Thu 1/1009:45 -
2 stops27h 15m
Deal found 31/8£575
Fri 16/1006:20 -
2 stops43h 17m
Fri 23/1015:30 -
2 stops34h 35m
Deal found 1/9£577
Fri 18/906:20 -
2 stops20h 11m
Thu 1/1015:30 -
2 stops38h 45m
Deal found 28/8£579
Sat 17/1011:10 -
1 stop15h 21m
Thu 29/1009:30 -
1 stop16h 35m
Deal found 31/8£581
Sat 12/1211:15 -
1 stop14h 47m
Tue 5/116:41 -
2 stops33h 24m
Deal found 2/9£582
Sat 19/911:10 -
1 stop15h 21m
Fri 2/1010:00 -
2 stops39h 55m
Deal found 29/8£583
Fri 11/1211:55 -
2 stops38h 07m
Tue 5/116:41 -
2 stops33h 24m
Deal found 28/8£584
Sun 1/1111:15 -
1 stop14h 47m
Thu 12/1110:00 -
2 stops40h 50m
Deal found 31/8£587
Mon 12/1011:10 -
1 stop15h 21m
Mon 19/1009:45 -
1 stop15h 00m
Deal found 28/8£588
Sat 31/1010:00 -
2 stops40h 02m
Wed 11/1110:00 -
2 stops21h 15m
Deal found 29/8£590

Find flight deals from Bruxelles-National to Panama City

Round-trip from

£547

One-way from

£477

Popular in

May

Cheapest in

February

Average price

£575
Air Europa
  • Air Europa
  • 1/11-12/11
  • 2 total stops
  • 45h 05m total
  • Brussels to Panama City
Search Deals
27/10
  • 27/10
  • 2 total stops
  • 16h 45m total
  • Brussels to Panama City
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£47 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£9 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Panama City that are best for you.

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Fly to

Route

Depart

Return

Price

Cheapest return flight

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Fri 25/9

06:20-19:31

2 stops20h 11m

Panama City Tocumen Intl

Fri 9/10

09:45-08:55

2 stops40h 10m

£575

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Fri 16/10

06:20-18:37

2 stops43h 17m

Panama City Tocumen Intl

Fri 23/10

15:30-09:05

2 stops34h 35m

£577
Fastest return journey

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Thu 24/9

08:35-19:31

2 stops17h 56m

Panama City Tocumen Intl

Thu 1/10

09:45-07:45

1 stop15h 00m

£577

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Sun 7/2

08:25-20:02

2 stops41h 37m

Panama City Tocumen Intl

Thu 11/2

10:00-13:15

2 stops45h 15m

£581

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Sat 12/12

11:15-20:02

1 stop14h 47m

Panama City Tocumen Intl

Wed 6/1

16:41-08:05

2 stops33h 24m

£581

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Sat 30/1

08:25-14:45

2 stops36h 20m

Panama City Tocumen Intl

Sat 13/2

11:35-08:05

2 stops38h 30m

£582

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Sat 12/12

11:15-20:02

1 stop14h 47m

Panama City Tocumen Intl

Tue 5/1

16:41-08:05

2 stops33h 24m

£582

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Mon 28/12

11:55-05:10

2 stops23h 15m

Panama City Tocumen Intl

Fri 8/1

11:35-08:05

2 stops38h 30m

£583
Cheapest one-way
Fastest single journey

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Tue 27/10

06:30-17:15

2 stops16h 45m

£477

BrusselsPanama City

BRU Brussels Bruxelles-National - PTY Panama City Tocumen Intl

BRUPTY

Brussels Bruxelles-National

Sun 27/12

08:05-20:00

2 stops17h 55m

£689

Flights are sorted by cheapest return flights first.

Deals found on 28/8

Showing 1-10 of 12 resultsSorted by cheapest first
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Best time to book a flight from Bruxelles-National to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Bruxelles-National with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Brussels Bruxelles-National Airport to Panama City

How far ahead should I book a flight from Brussels Bruxelles-National Airport to Panama City?

The best time to book flights from Brussels Bruxelles-National Airport to Panama City is 1 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Panama City?

Currently, February is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Panama City (average of £508). Flying from Brussels Bruxelles-National Airport to Panama City in May is currently the most expensive (average of £729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Brussels Bruxelles-National Airport to Panama City?

Airfare is below average for this route at the moment.

Brussels Bruxelles-National Airport to Panama City flights typically cost between £569 and £635 in November.
The cheapest return price found within the last 5 days was £547 on Air Europa (1 Nov–12 Nov).

Related info for your journey

  • What airport do you fly into for flights to Panama City from Brussels Bruxelles-National?

    If you book a flight to Panama City from Brussels Bruxelles-National, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Brussels Bruxelles-National to Tocumen Intl per day from 0 different airlines.

  • How long is the flight from Brussels Bruxelles-National Airport to Panama City?

    Departing from Brussels Bruxelles-National Airport to Panama City will take you 20h 11m. The distance from Brussels Bruxelles-National Airport to Panama City is about 5462 mi.

  • Can I find deals for flights from Bruxelles-National to Panama City that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Panama City.

  • Can I find deals for business class flights from Bruxelles-National to Panama City?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Panama City?

    Currently, February is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Panama City (average of £508). Flying from Brussels Bruxelles-National Airport to Panama City in May is currently the most expensive (average of £729). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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