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Cheap flights from Frankfurt am Main Airport to Panama City from £442

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/6. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — PTY
18 Jun — 25 Jun1
1 adult

Cheap flight deals from Frankfurt to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 13 June 2025.

Round-trip from

£465

One-way from

£442

Popular in

December

Cheapest in

May

Average price

£443
United Airlines
  • United Airlines
  • 2/9-16/9
  • 4 total stops
  • 45h 35m total
  • Frankfurt am Main to Panama City
Air Europa
  • Air Europa
  • 19/6
  • 1 total stop
  • 14h 45m total
  • Frankfurt am Main to Panama City
Highest demand for flights based on searches. 12% potential increase in price (£55 potential increase over avg. return price).
Cheapest flight prices on average. 4% potential price decrease (£18 potential savings vs. average return price).
Average for round-trip flights in June 2025

Find flight deals from Frankfurt to Panama City

Cheapest flights from Frankfurt to Panama City
Explore the most affordable flight options available from Frankfurt to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 June 2025.

Tue 2/917:35FRA - PTY
2 stops27h 15mUnited Airlines
Tue 16/909:45PTY - FRA
2 stops18h 20mUnited Airlines
Deal found 11/6£465
Sun 15/621:50FRA - PTY
Nonstop11h 50mMultiple Airlines
Mon 30/612:48PTY - FRA
1 stop17h 47mMultiple Airlines
Deal found 12/6£510
Sat 20/910:55FRA - PTY
1 stop14h 45mAir Europa
Mon 6/1020:25PTY - FRA
1 stop14h 25mAir Europa
Deal found 11/6£520
Mon 29/1207:05FRA - PTY
1 stop18h 45mTurkish Airlines
Fri 6/318:45PTY - FRA
1 stop37h 10mTurkish Airlines
Deal found 11/6£606
Sat 18/1010:40FRA - PTY
1 stop33h 07mDelta
Thu 30/1014:12PTY - FRA
2 stops35h 38mDelta
Deal found 11/6£635
Mon 17/1110:30FRA - PTY
Nonstop12h 15mCondor
Mon 1/1218:45PTY - FRA
Nonstop11h 10mCondor
Deal found 12/6£640
Sun 15/606:30FRA - PTY
2 stops20h 45mIberia
Mon 30/617:10PTY - FRA
1 stop19h 10mIberia
Deal found 12/6£673
Fri 5/910:15FRA - PTY
1 stop13h 35mKLM
Fri 19/1218:45PTY - FRA
1 stop32h 50mKLM
Deal found 11/6£680

Cheapflights Fare Finder

Customise your flight search to find flights from Frankfurt to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 13 June 2025.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Panama City that are best for you.

Fly from

Frankfurt

Fly to

Panama City

Route

Depart

Return

Price

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Tue 2/9

17:35-13:50

2 stops27h 15m

Panama City Tocumen Intl

Tue 16/9

09:45-11:05

2 stops18h 20m

£465

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 19/9

10:55-18:40

1 stop14h 45m

Panama City Tocumen Intl

Sun 5/10

20:25-09:45

1 stop30h 20m

£484

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 28/11

14:50-19:50

1 stop35h 00m

Panama City Tocumen Intl

Mon 8/12

21:45-09:30

1 stop29h 45m

£607

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sat 18/10

10:40-12:47

1 stop33h 07m

Panama City Tocumen Intl

Thu 30/10

14:12-07:50

2 stops35h 38m

£635

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Mon 17/11

10:30-16:45

Nonstop12h 15m

Panama City Tocumen Intl

Mon 1/12

18:45-11:55

Nonstop11h 10m

£640

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 5/9

10:15-16:50

1 stop13h 35m

Panama City Tocumen Intl

Fri 19/12

18:45-09:35

1 stop32h 50m

£680

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sun 19/10

07:00-17:45

2 stops17h 45m

Panama City Tocumen Intl

Sun 2/11

22:20-22:05

1 stop17h 45m

£702

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Thu 19/6

10:55-18:40

1 stop14h 45m

£442

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 12/11

10:45-00:20

2 stops19h 35m

£474

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 20/6

20:00-08:55

2 stops19h 55m

£525

Flights are sorted by cheapest return flights first.

Deals found on 13/6

Showing 1-10 of 14 results
1
2

Best time to book a flight from Frankfurt to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Frankfurt with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Panama City

How far ahead should I book a flight from Frankfurt am Main Airport to Panama City?

Use this chart to determine the optimal time to book a return flight from Frankfurt to Panama City. Price data was last updated on 9 June 2025.

To ensure you get the cheapest price possible for a flight from Frankfurt am Main Airport to Panama City, you should look to book at least 59 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

Currently, April is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £763). Flying from Frankfurt am Main Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 13 June 2025.
To help decide which airline to fly from Frankfurt am Main to Panama City, see what other customers have to say about Delta, KLM and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
8.0
Very Good

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from Frankfurt am Main?

    For a flight from Frankfurt am Main to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from Frankfurt am Main per day. 0 airlines have flights to Panama City Tocumen Intl from Frankfurt am Main on a regular basis.

  • What are the cheapest airlines flying from Frankfurt am Main Airport to Panama City round-trip?

    Our cheapest airline available from Frankfurt am Main Airport to Panama City is United Airlines. Our recent data shows that you can find tickets from as low as £465 on this airline. Additional options worth looking into are Air Europa and Turkish Airlines, starting at £484 and £607 round-trip. United Airlines is 14% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Frankfurt am Main Airport to Panama City one-way?

    To fly one-way, consider booking your trip with Air Europa, which is currently one of the cheapest options available, starting at £442. Avianca flights start at £525 while deals on Condor start at £592 one-way.

  • Can I find deals for flights from Frankfurt to Panama City that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Panama City.

  • Can I find deals for business class flights from Frankfurt to Panama City?

    Yes. Cheapflights offers flight deals from Frankfurt to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £763). Flying from Frankfurt am Main Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Frankfurt am Main Airport?

Book flights to Frankfurt am Main Airport if you plan to visit one of these locations
San Blas

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