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Cheap flights from Frankfurt am Main Airport to Panama City from £528

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 14/4. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — PTY
13 Apr — 20 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Frankfurt to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Frankfurt to Panama City
Explore the most affordable flight options available from Frankfurt to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 14 March 2026.

Tue 14/410:55
FRA
-
PTY
1 stop14h 45m
Air Europa
Mon 4/520:25
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 9/3£528
Thu 14/519:10
FRA
-
PTY
1 stop30h 30m
Air Europa
Tue 26/520:25
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 13/3£532
Wed 20/510:55
FRA
-
PTY
1 stop14h 45m
Air Europa
Sat 6/620:25
PTY
-
FRA
1 stop30h 20m
Air Europa
Deal found 12/3£533
Fri 17/419:10
FRA
-
PTY
1 stop30h 30m
Air Europa
Mon 4/520:25
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 9/3£536
Sat 14/1110:45
FRA
-
PTY
1 stop15h 00m
Air Europa
Tue 1/1221:30
PTY
-
FRA
1 stop14h 20m
Air Europa
Deal found 13/3£539
Tue 15/910:55
FRA
-
PTY
1 stop14h 45m
Air Europa
Thu 24/920:25
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 10/3£541
Sun 24/519:10
FRA
-
PTY
1 stop30h 30m
Air Europa
Sat 6/620:25
PTY
-
FRA
1 stop30h 20m
Air Europa
Deal found 12/3£541
Wed 28/1010:45
FRA
-
PTY
1 stop15h 00m
Air Europa
Tue 24/1121:30
PTY
-
FRA
1 stop14h 20m
Air Europa
Deal found 12/3£542
Sun 15/1119:05
FRA
-
PTY
1 stop30h 40m
Air Europa
Thu 3/1221:30
PTY
-
FRA
1 stop14h 20m
Air Europa
Deal found 13/3£547
Sun 1/1119:05
FRA
-
PTY
1 stop30h 40m
Air Europa
Fri 20/1121:30
PTY
-
FRA
1 stop14h 20m
Air Europa
Deal found 12/3£550
Wed 11/1119:05
FRA
-
PTY
1 stop30h 40m
Air Europa
Wed 18/1121:30
PTY
-
FRA
1 stop14h 20m
Air Europa
Deal found 9/3£551
Sun 13/911:45
FRA
-
PTY
1 stop36h 05m
KLM
Sun 20/918:50
PTY
-
FRA
1 stop20h 10m
KLM
Deal found 12/3£552

Find flight deals from Frankfurt to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 14 March 2026.

Round-trip from

£528

Popular in

July

Cheapest in

June

Average price

£613
Air Europa
  • Air Europa
  • 14/4-4/5
  • 2 total stops
  • 29h 10m total
  • Frankfurt am Main to Panama City
Search Deals
Highest demand for flights based on searches. 0% potential increase in price (£3 potential increase over avg. return price).
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Cheapest flight prices on average. 1% potential price decrease (£7 potential savings vs. average return price).
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Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customise your flight search to find flights from Frankfurt to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 14 March 2026.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sat 30/5

10:15-16:50

1 stop13h 35m

Panama City Tocumen Intl

Sun 28/6

21:55-22:00

2 stops17h 05m

£539
Fastest return journey

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Thu 18/6

10:55-18:40

1 stop14h 45m

Panama City Tocumen Intl

Mon 22/6

20:25-17:50

1 stop14h 25m

£560

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Thu 18/6

07:45-19:31

2 stops18h 46m

Panama City Tocumen Intl

Mon 22/6

15:30-11:15

1 stop36h 45m

£570

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 21/8

06:35-19:31

2 stops19h 56m

Panama City Tocumen Intl

Sat 5/9

10:00-11:15

1 stop18h 15m

£572

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sat 8/8

17:10-14:14

2 stops28h 04m

Panama City Tocumen Intl

Sat 22/8

10:00-12:10

2 stops19h 10m

£576

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 5/8

12:40-04:04

2 stops22h 24m

Panama City Tocumen Intl

Fri 14/8

10:00-14:05

2 stops21h 05m

£576
Cheapest one-way

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Tue 14/7

10:55-18:40

1 stop14h 45m

£535

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 18/3

06:30-16:45

1 stop16h 15m

£535

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Thu 19/3

11:50-16:30

1 stop34h 40m

£697
Fastest single journey

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Thu 16/4

10:15-16:50

1 stop13h 35m

£741

Flights are sorted by cheapest return flights first.

Deals found on 12/3

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Best time to book a flight from Frankfurt to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Frankfurt with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Panama City

How far ahead should I book a flight from Frankfurt am Main Airport to Panama City?

Use this chart to determine the optimal time to book a return flight from Frankfurt to Panama City. Price data was last updated on 13 March 2026.

To ensure you get the cheapest price possible for a flight from Frankfurt am Main Airport to Panama City, you should look to book at least 63 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

Currently, June is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £291). Flying from Frankfurt am Main Airport to Panama City in July is currently the most expensive (average of £497). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Frankfurt am Main Airport to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Frankfurt am Main?

    For a flight from Frankfurt am Main to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from Frankfurt am Main per day. 0 airlines have flights to Panama City Tocumen Intl from Frankfurt am Main on a regular basis.

  • How long is the flight from Frankfurt am Main Airport to Panama City?

    Departing from Frankfurt am Main Airport to Panama City will take you 13h 35m. Airlines will cover a distance of 5644 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Frankfurt to Panama City that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Panama City.

  • Can I find deals for business class flights from Frankfurt to Panama City?

    Yes. Cheapflights offers flight deals from Frankfurt to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £291). Flying from Frankfurt am Main Airport to Panama City in July is currently the most expensive (average of £497). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Why should you use Cheapflights to find cheap flight tickets from Frankfurt to Panama City?

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Yes! Cheapflights helps users easily find flights from Frankfurt to Panama City with no change fees.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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