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Cheap flights from Frankfurt am Main Airport to Panama City from £318

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/3. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — PTY
27 fev — 6 mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Frankfurt to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Frankfurt to Panama City
Explore the most affordable flight options available from Frankfurt to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 janeiro 2026.

qua 4/310:45
FRA
-
PTY
1 stop15h 00m
Air Europa
dom 15/321:30
PTY
-
FRA
1 stop30h 15m
Air Europa
Deal found 25/1£523
qui 19/319:05
FRA
-
PTY
1 stop30h 40m
Air Europa
ter 31/320:25
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 25/1£524
ter 5/510:55
FRA
-
PTY
1 stop14h 45m
Air Europa
qui 28/520:25
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 27/1£526
sex 6/310:45
FRA
-
PTY
1 stop15h 00m
Air Europa
seg 23/321:30
PTY
-
FRA
1 stop30h 15m
Air Europa
Deal found 26/1£530
qua 4/310:45
FRA
-
PTY
1 stop15h 00m
Air Europa
qua 11/321:30
PTY
-
FRA
1 stop30h 15m
Air Europa
Deal found 27/1£531
dom 8/319:05
FRA
-
PTY
1 stop30h 40m
Air Europa
qua 1/420:25
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 27/1£534
sáb 9/510:15
FRA
-
PTY
2 stops16h 30m
Multiple Airlines
dom 17/521:55
PTY
-
FRA
1 stop33h 25m
Multiple Airlines
Deal found 25/1£534
seg 13/406:35
FRA
-
PTY
2 stops19h 56m
United Airlines
seg 27/407:55
PTY
-
FRA
1 stop20h 20m
United Airlines
Deal found 26/1£537
qui 16/406:35
FRA
-
PTY
2 stops19h 56m
United Airlines
qua 29/407:55
PTY
-
FRA
1 stop17h 20m
United Airlines
Deal found 27/1£537
seg 20/407:45
FRA
-
PTY
2 stops27h 19m
United Airlines
ter 5/509:45
PTY
-
FRA
2 stops25h 20m
United Airlines
Deal found 27/1£539
qua 11/313:50
FRA
-
PTY
1 stop29h 55m
United Airlines
qua 18/315:41
PTY
-
FRA
1 stop35h 19m
United Airlines
Deal found 24/1£539

Find flight deals from Frankfurt to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 janeiro 2026.

Round-trip from

£523

One-way from

£318

Popular in

July

Cheapest in

May

Average price

£605
Air Europa
  • Air Europa
  • 4/3-15/3
  • 2 total stops
  • 45h 15m total
  • Frankfurt am Main to Panama City
Search Deals
KLM
  • KLM
  • 18/3
  • 2 total stops
  • 15h 55m total
  • Frankfurt am Main to Panama City
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (£15 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£9 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Frankfurt to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 28 janeiro 2026.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Panama City that are best for you.

Fly from

Frankfurt

Fly to

Panama City

Route

Depart

Return

Price

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

qui 21/5

10:55-18:40

1 stop14h 45m

Panama City Tocumen Intl

seg 25/5

20:25-17:50

1 stop14h 25m

£524

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

dom 15/3

10:45-19:45

1 stop15h 00m

Panama City Tocumen Intl

ter 31/3

20:25-17:50

1 stop14h 25m

£526

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

qua 6/5

10:55-18:40

1 stop14h 45m

Panama City Tocumen Intl

ter 26/5

20:25-17:50

1 stop14h 25m

£526

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

qui 21/5

07:45-19:31

2 stops18h 46m

Panama City Tocumen Intl

seg 25/5

09:45-09:10

1 stop16h 25m

£537

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

qua 11/3

13:50-13:45

1 stop29h 55m

Panama City Tocumen Intl

qua 18/3

15:41-09:00

1 stop35h 19m

£539

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

dom 8/3

12:15-04:10

2 stops21h 55m

Panama City Tocumen Intl

qui 26/3

07:55-11:40

1 stop21h 45m

£540

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

dom 8/3

12:15-04:10

2 stops21h 55m

Panama City Tocumen Intl

qua 25/3

09:30-14:05

2 stops22h 35m

£542

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

sáb 14/2

17:25-17:07

2 stops29h 42m

Panama City Tocumen Intl

sex 27/2

16:41-06:35

2 stops31h 54m

£542

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

seg 30/3

13:55-14:14

1 stop31h 19m

Panama City Tocumen Intl

qua 22/4

07:55-11:15

1 stop20h 20m

£542

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

qua 18/3

10:15-20:10

2 stops15h 55m

£318

Flights are sorted by cheapest return flights first.

Deals found on 25/1

Showing 1-10 of 15 results
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Best time to book a flight from Frankfurt to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Frankfurt with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Panama City

How far ahead should I book a flight from Frankfurt am Main Airport to Panama City?

Use this chart to determine the optimal time to book a return flight from Frankfurt to Panama City. Price data was last updated on 23 January 2026.

To ensure you get the cheapest price possible for a flight from Frankfurt am Main Airport to Panama City, you should look to book at least 63 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

Currently, June is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £286). Flying from Frankfurt am Main Airport to Panama City in July is currently the most expensive (average of £479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Frankfurt am Main Airport to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Frankfurt am Main?

    For a flight from Frankfurt am Main to Panama City, you will be flying into Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city. Tocumen Intl is the only Panama City airport and it handles 0 inbound flights from Frankfurt am Main per day. 0 airlines have flights to Panama City Tocumen Intl from Frankfurt am Main on a regular basis.

  • How long is the flight from Frankfurt am Main Airport to Panama City?

    Departing from Frankfurt am Main Airport to Panama City will take you 14h 45m. Airlines will cover a distance of 5644 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Frankfurt to Panama City that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Panama City.

  • Can I find deals for business class flights from Frankfurt to Panama City?

    Yes. Cheapflights offers flight deals from Frankfurt to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of £286). Flying from Frankfurt am Main Airport to Panama City in July is currently the most expensive (average of £479). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Why should you use Cheapflights to find cheap flight tickets from Frankfurt to Panama City?

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Yes! Cheapflights helps users easily find flights from Frankfurt to Panama City with no change fees.

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