Cheap flights from Southampton to San Francisco from £378
This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SFO
10 Dec — 17 Dec1
Return
1 adult
Economy
Return
1 adult, Economy, 0 bags
Cheap flight deals from Southampton to San Francisco
Enter your travel dates to find the best prices.
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Best
Last-minute
One-way
Cheapest flights from Southampton to San Francisco
Explore the most affordable flight options available from Southampton to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 November 2026.
Thu 24/1217:35 -
1 stop26h 10m
Thu 31/1208:00 -
2 stops25h 05m
Deal found 8/11£685
Thu 3/1208:40 -
1 stop35h 05m
Fri 11/1223:39 -
2 stops25h 16m
Deal found 8/11£715
Mon 30/1117:45 -
2 stops38h 27m
Wed 16/1212:08 -
2 stops20h 57m
Deal found 8/11£719
Tue 15/1208:40 -
2 stops19h 58m
Tue 22/1222:00 -
2 stops26h 10m
Deal found 7/11£721
Thu 3/1208:40 -
1 stop35h 05m
Thu 10/1213:50 -
1 stop35h 05m
Deal found 8/11£756
Mon 30/1117:45 -
2 stops36h 49m
Mon 14/1213:50 -
1 stop19h 15m
Deal found 8/11£760
Thu 10/1212:25 -
1 stop35h 10m
Thu 17/1207:50 -
2 stops17h 00m
Deal found 9/11£789
Tue 1/1209:20 -
1 stop14h 15m
Mon 14/1217:20 -
1 stop18h 10m
Deal found 8/11£792
Tue 15/1217:35 -
1 stop26h 10m
Thu 24/1222:55 -
2 stops33h 55m
Deal found 7/11£804
Mon 30/1120:00 -
1 stop27h 35m
Sun 13/1217:20 -
1 stop31h 30m
Deal found 8/11£813
Best flights from Southampton to San Francisco
Discover carefully curated flight deals from Southampton to San Francisco that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 10 November 2026.
Thu 24/1208:40 -
2 stops23h 18m
Thu 31/1210:02 -
2 stops23h 03m
Deal found 8/11£689
Wed 17/219:45 -
2 stops51h 50m
Sun 21/217:20 -
1 stop18h 10m
Deal found 10/11£829
Thu 3/1208:40 -
1 stop35h 05m
Fri 11/1223:39 -
2 stops25h 16m
Deal found 8/11£715
Mon 30/1117:45 -
2 stops38h 27m
Fri 11/1222:40 -
2 stops26h 15m
Deal found 8/11£719
Wed 27/119:45 -
2 stops51h 50m
Sun 31/117:20 -
1 stop34h 30m
Deal found 7/11£833
Thu 3/1208:40 -
2 stops21h 04m
Tue 15/1223:39 -
2 stops33h 26m
Deal found 8/11£719
Tue 5/120:00 -
1 stop27h 35m
Fri 11/621:00 -
2 stops27h 25m
Deal found 6/11£861
Mon 4/119:45 -
2 stops51h 50m
Sun 13/621:00 -
2 stops27h 25m
Deal found 6/11£889
Wed 30/1208:40 -
2 stops34h 37m
Tue 15/614:00 -
2 stops19h 00m
Deal found 6/11£865
Mon 4/120:00 -
1 stop27h 35m
Fri 11/621:00 -
2 stops27h 25m
Deal found 6/11£890
Last-minute flights from Southampton to San Francisco
Discover last-minute flight deals from Southampton to San Francisco. Data last updated 10 November 2026 and is based on user searches.
Mon 30/1117:45 -
2 stops38h 27m
Wed 16/1212:08 -
2 stops20h 57m
Deal found 8/11£719
Mon 30/1117:45 -
2 stops36h 49m
Thu 10/1216:05 -
2 stops32h 50m
Deal found 8/11£760
Mon 30/1120:00 -
1 stop27h 35m
Sun 13/1217:20 -
1 stop31h 30m
Deal found 8/11£813
Tue 1/1209:20 -
1 stop14h 15m
Mon 14/1217:20 -
1 stop18h 10m
Deal found 8/11£792
Thu 3/1208:40 -
1 stop35h 05m
Fri 11/1223:39 -
2 stops25h 16m
Deal found 8/11£715
Thu 3/1208:40 -
1 stop35h 05m
Thu 10/1213:50 -
1 stop35h 05m
Deal found 8/11£756
Thu 10/1212:25 -
1 stop35h 10m
Thu 17/1207:50 -
2 stops17h 00m
Deal found 9/11£789
Tue 15/1208:40 -
2 stops19h 58m
Tue 22/1222:00 -
2 stops26h 10m
Deal found 7/11£721
Tue 15/1217:35 -
1 stop26h 10m
Thu 24/1222:55 -
2 stops33h 55m
Deal found 7/11£804
Thu 24/1217:35 -
1 stop26h 10m
Thu 31/1208:00 -
2 stops25h 05m
Deal found 8/11£685
One-way flights from Southampton to San Francisco
Search for one-way flight options from Southampton to San Francisco. Find affordable one-way fares based on user searches. Data last updated 10 November 2026.
Mon 11/115:30 -
3 stops55h 15m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 7/11£378
Sun 10/120:00 -
3 stops47h 45m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 7/11£411
Mon 11/109:20 -
1 stop14h 15m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 7/11£434
Mon 22/209:20 -
1 stop14h 15m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 10/11£492
Sun 10/120:00 -
1 stop27h 35m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 7/11£495
Wed 28/409:20 -
1 stop14h 30m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 10/11£496
Tue 19/112:20 -
1 stop35h 15m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 10/11£498
Sat 24/409:20 -
1 stop14h 30m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 8/11£501
Tue 12/112:20 -
1 stop35h 15m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 8/11£503
Mon 11/109:20 -
1 stop14h 15m
Wed 31/1200:00 -
Nonstop0h 00m
Deal found 8/11£504
Find flight deals from Southampton to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 10 November 2026.
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated 10 November 2026.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest return flight
Fastest return journey
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Wed 28/4
09:20-15:50
1 stop14h 30m
San Francisco
Wed 31/12
00:00-09:00
Nonstop0h 00m
£508
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Mon 26/4
09:20-15:50
1 stop14h 30m
San Francisco
Wed 31/12
00:00-09:00
Nonstop0h 00m
£508
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Sun 25/4
09:20-15:50
1 stop14h 30m
San Francisco
Wed 31/12
00:00-09:00
Nonstop0h 00m
£508
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Thu 29/4
09:20-15:50
1 stop14h 30m
San Francisco
Wed 31/12
00:00-09:00
Nonstop0h 00m
£508
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Fri 23/4
09:20-15:50
1 stop14h 30m
San Francisco
Wed 31/12
00:00-09:00
Nonstop0h 00m
£508
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Tue 27/4
09:20-15:50
1 stop14h 30m
San Francisco
Wed 31/12
00:00-09:00
Nonstop0h 00m
£510
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Fri 30/4
09:20-15:50
1 stop14h 30m
San Francisco
Wed 31/12
00:00-09:00
Nonstop0h 00m
£526
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Thu 24/12
08:40-23:58
2 stops23h 18m
San Francisco
Thu 31/12
10:02-17:05
2 stops23h 03m
£689
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Thu 3/12
08:40-11:45
1 stop35h 05m
San Francisco
Fri 11/12
23:39-08:55
2 stops25h 16m
£715
SouthamptonSan Francisco
SOU Southampton Eastleigh - SFO San Francisco
SOUSFO
Southampton Eastleigh
Mon 30/11
17:45-00:12
2 stops38h 27m
San Francisco
Fri 11/12
22:40-08:55
2 stops26h 15m
£719
Flights are sorted by cheapest return flights first.
Deals found on 9/11
Showing 1-10 of 17 resultsSorted by cheapest first
1
2
Best time to book a flight from Southampton to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Southampton with our price prediction graph.
SOU-SFO
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Southampton to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
How long is the flight from Southampton to San Francisco?
Delta and British Airways can get you from Southampton to San Francisco in just under 23h 18m. Your travel time can differ by up to 28h 32m. Southampton and San Francisco are separated by a distance of 5349 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
Can I find deals for flights from Southampton to San Francisco that include hotel bookings?
Yes. In addition to deals on Southampton to San Francisco flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Southampton to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to San Francisco.
Can I find deals for business class flights from Southampton to San Francisco?
Yes. Cheapflights offers flight deals from Southampton to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
Browse through other flights departing from Southampton. Flights are based on user searches made on Cheapflights and were last updated on 10 November 2026.
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 10 November 2026.
Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Southampton to San Francisco?
Cheapflights helps you search for flights from Southampton to San Francisco via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.
Why should you use Cheapflights to find cheap flight tickets from Southampton to San Francisco?
It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Southampton to San Francisco.
Can Cheapflights find flights from Southampton to San Francisco with no change fees?
Need flexible booking options for your flight to San Francisco from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.
Can Cheapflights notify me if prices for flights from Southampton to San Francisco become cheaper?
Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to San Francisco from Southampton today and book when prices fit your budget.
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