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Cheap flights from Southampton to San Francisco from £439

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SFO
18 Oct — 25 Oct1
1 adult
1 adult, Economy

Cheap flight deals from Southampton to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 September 2025.

Round-trip from

£484

One-way from

£439

Popular in

July

Cheapest in

February

Average price

£421
Delta
  • Delta
  • 1/11-7/11
  • 4 total stops
  • 44h 20m total
  • Southampton to San Francisco
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British Airways
  • British Airways
  • 10/11
  • 1 total stop
  • 14h 05m total
  • Southampton to San Francisco
Search Deals
Highest demand for flights based on searches. 15% potential increase in price (£63 potential increase over avg. return price).
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Cheapest flight prices on average. 2% potential price decrease (£11 potential savings vs. average return price).
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Average for round-trip flights in September 2025
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Find flight deals from Southampton to San Francisco

Cheapest flights from Southampton to San Francisco
Explore the most affordable flight options available from Southampton to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 September 2025.

Sat 1/1109:25SOU - SFO
2 stops20h 05mDelta
Fri 7/1100:35SFO - SOU
2 stops24h 15mDelta
Deal found 17/9£484
Sat 1/1109:25SOU - SFO
2 stops20h 05mKLM
Sat 8/1113:55SFO - SOU
1 stop34h 15mKLM
Deal found 17/9£493
Sat 1/1109:30SOU - SFO
1 stop14h 05mAer Lingus
Sat 8/1117:20SFO - SOU
1 stop18h 20mAer Lingus
Deal found 17/9£503
Fri 7/1109:30SOU - SFO
1 stop14h 05mBritish Airways
Tue 11/1117:20SFO - SOU
1 stop18h 20mBritish Airways
Deal found 15/9£585
Tue 30/919:55SOU - SFO
2 stops29h 30mBritish Airways
Tue 7/1017:40SFO - SOU
1 stop17h 50mBritish Airways
Deal found 16/9£747
Sat 1/1117:30SOU - SFO
3 stops29h 05mMultiple Airlines
Sat 8/1116:40SFO - SOU
3 stops31h 30mMultiple Airlines
Deal found 17/9£867

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 September 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Southampton

Fly to

San Francisco

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 1/11

09:25-22:30

2 stops20h 05m

San Francisco

Fri 7/11

00:35-08:50

2 stops24h 15m

£484

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 1/11

09:25-22:30

2 stops20h 05m

San Francisco

Sat 8/11

07:15-08:50

2 stops17h 35m

£484

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 1/11

09:30-16:35

1 stop14h 05m

San Francisco

Sat 8/11

17:20-19:40

1 stop18h 20m

£503

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 7/11

09:30-15:35

1 stop14h 05m

San Francisco

Tue 11/11

17:20-19:40

1 stop18h 20m

£585

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 30/9

19:55-17:25

2 stops29h 30m

San Francisco

Tue 7/10

17:40-19:30

1 stop17h 50m

£747

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 1/11

09:40-12:50

2 stops34h 10m

San Francisco

Sat 8/11

16:35-11:50

3 stops35h 15m

£955

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 10/11

09:30-15:35

1 stop14h 05m

£439

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 6/11

19:55-15:00

2 stops27h 05m

£545

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 31/12

08:40-15:00

2 stops38h 20m

£607

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 7/10

09:10-15:55

1 stop14h 45m

£630

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 14 results
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Best time to book a flight from Southampton to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to San Francisco

What is the cheapest month to book a flight from Southampton to San Francisco?

Currently, February is the cheapest month in which you can book a flight from Southampton to San Francisco (average of £538). Flying from Southampton to San Francisco in July is currently the most expensive (average of £803). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Southampton to San Francisco?

    Delta, KLM, and Aer Lingus can get you from Southampton to San Francisco in just under 14h 05m. Your travel time can differ by up to 6h. Southampton and San Francisco are separated by a distance of 5349 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Southampton to San Francisco that include hotel bookings?

    Yes. In addition to deals on Southampton to San Francisco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to San Francisco.

  • Can I find deals for business class flights from Southampton to San Francisco?

    Yes. Cheapflights offers flight deals from Southampton to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to San Francisco?

    Currently, February is the cheapest month in which you can book a flight from Southampton to San Francisco (average of £538). Flying from Southampton to San Francisco in July is currently the most expensive (average of £803). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Newark
South San Francisco
Bodega Bay
Pacific Grove

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to San Francisco?

Cheapflights helps you search for flights from Southampton to San Francisco via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Southampton to San Francisco?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Southampton to San Francisco.

Can Cheapflights find flights from Southampton to San Francisco with no change fees?

Need flexible booking options for your flight to San Francisco from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Southampton to San Francisco become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to San Francisco from Southampton today and book when prices fit your budget.

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