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Cheap flights from Southampton to San Francisco from £476

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SFO
6 Mar — 13 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to San Francisco

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to San Francisco
Explore the most affordable flight options available from Southampton to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 4 February 2026.

Sat 29/818:50
SOU
-
SFO
1 stop34h 00m
Multiple Airlines
Tue 8/916:05
SFO
-
SOU
1 stop14h 55m
Multiple Airlines
Deal found 4/2£582
Sat 29/817:30
SOU
-
SFO
1 stop26h 15m
KLM
Tue 8/913:00
SFO
-
SOU
2 stops19h 50m
KLM
Deal found 4/2£648
Thu 19/308:50
SOU
-
SFO
2 stops20h 46m
KLM
Thu 26/314:55
SFO
-
SOU
1 stop34h 55m
KLM
Deal found 2/2£649
Thu 19/318:05
SOU
-
SFO
1 stop25h 45m
Multiple Airlines
Thu 26/314:55
SFO
-
SOU
1 stop19h 05m
Multiple Airlines
Deal found 2/2£700
Fri 27/220:10
SOU
-
SFO
1 stop27h 25m
British Airways
Mon 2/317:20
SFO
-
SOU
1 stop14h 15m
British Airways
Deal found 2/2£741
Wed 29/409:10
SOU
-
SFO
1 stop14h 40m
British Airways
Sun 3/516:35
SFO
-
SOU
2 stops18h 50m
British Airways
Deal found 3/2£757

Find flight deals from Southampton to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 4 February 2026.

Round-trip from

£649

One-way from

£476

Popular in

July

Cheapest in

February

Average price

£411
KLM
  • KLM
  • 19/3-26/3
  • 3 total stops
  • 55h 41m total
  • Southampton to San Francisco
Search Deals
British Airways
  • British Airways
  • 6/5
  • 1 total stop
  • 14h 40m total
  • Southampton to San Francisco
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (£53 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£9 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 February 2026.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Southampton

Fly to

San Francisco

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 19/3

08:50-22:36

2 stops20h 46m

San Francisco

Thu 26/3

14:55-08:50

1 stop34h 55m

£649

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 19/3

18:05-12:50

1 stop25h 45m

San Francisco

Thu 26/3

14:55-17:00

1 stop19h 05m

£700

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 27/2

20:10-15:35

1 stop27h 25m

San Francisco

Mon 2/3

17:20-15:35

1 stop14h 15m

£741

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 29/4

09:10-15:50

1 stop14h 40m

San Francisco

Sun 3/5

16:35-19:25

2 stops18h 50m

£757

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 31/5

20:45-13:50

2 stops49h 05m

£510

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 2/6

15:15-13:50

2 stops30h 35m

£510

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 24/6

09:10-15:50

1 stop14h 40m

£525

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 23/6

09:10-15:50

1 stop14h 40m

£525

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 6/5

19:55-17:40

2 stops29h 45m

£525

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 10/6

09:10-15:50

1 stop14h 40m

£525

Flights are sorted by cheapest return flights first.

Deals found on 3/2

Showing 1-10 of 16 results
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Best time to book a flight from Southampton to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to San Francisco

What is the cheapest month to book a flight from Southampton to San Francisco?

Currently, February is the cheapest month in which you can book a flight from Southampton to San Francisco (average of £346). Flying from Southampton to San Francisco in July is currently the most expensive (average of £435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Southampton to San Francisco?

    KLM and British Airways can get you from Southampton to San Francisco in just under 20h 46m. Your travel time can differ by up to 6h 39m. Southampton and San Francisco are separated by a distance of 5349 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Southampton to San Francisco that include hotel bookings?

    Yes. In addition to deals on Southampton to San Francisco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to San Francisco.

  • Can I find deals for business class flights from Southampton to San Francisco?

    Yes. Cheapflights offers flight deals from Southampton to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to San Francisco?

    Currently, February is the cheapest month in which you can book a flight from Southampton to San Francisco (average of £346). Flying from Southampton to San Francisco in July is currently the most expensive (average of £435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Newark
San Bruno
Bodega Bay
South San Francisco
Sunnyvale
Pacific Grove

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to San Francisco?

Cheapflights helps you search for flights from Southampton to San Francisco via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Southampton to San Francisco?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Southampton to San Francisco.

Can Cheapflights find flights from Southampton to San Francisco with no change fees?

Need flexible booking options for your flight to San Francisco from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Southampton to San Francisco become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to San Francisco from Southampton today and book when prices fit your budget.

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