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Cheap flights from Southampton to San Francisco from £454

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SFO
20 joulu — 27 joulu1
1 adult
1 adult, Economy, 0 bags

Find flight deals from Southampton to San Francisco

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to San Francisco
Explore the most affordable flight options available from Southampton to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 20 marraskuu 2025.

ma 22/1208:40SOU - SFO
1 stop35h 10mVirgin Atlantic
ma 29/1213:55SFO - SOU
1 stop34h 15mVirgin Atlantic
Deal found 18/11£483
ma 22/1218:05SOU - SFO
1 stop25h 45mDelta
ma 29/1223:45SFO - SOU
2 stops33h 15mDelta
Deal found 18/11£502
to 4/1218:05SOU - SFO
1 stop25h 45mDelta
su 18/113:55SFO - SOU
1 stop19h 10mDelta
Deal found 17/11£555
ke 3/1208:40SOU - SFO
1 stop35h 10mDelta
su 18/113:55SFO - SOU
1 stop19h 10mDelta
Deal found 17/11£557
pe 5/1208:40SOU - SFO
2 stops17h 24mDelta
su 18/114:05SFO - SOU
2 stops19h 00mDelta
Deal found 17/11£559
ke 3/1217:30SOU - SFO
1 stop26h 20mDelta
la 17/113:55SFO - SOU
1 stop19h 20mDelta
Deal found 17/11£561
ke 3/1217:30SOU - SFO
2 stops32h 46mDelta
ma 19/108:00SFO - SOU
2 stops16h 50mDelta
Deal found 17/11£561
ke 3/1217:30SOU - SFO
2 stops37h 35mDelta
pe 16/116:05SFO - SOU
2 stops41h 10mDelta
Deal found 17/11£565
ma 22/1208:40SOU - SFO
3 stops22h 18mMultiple Airlines
ma 29/1217:20SFO - SOU
2 stops30h 50mMultiple Airlines
Deal found 18/11£903
ma 1/1220:40SOU - SFO
2 stops26h 20mBritish Airways
ma 8/1217:20SFO - SOU
1 stop14h 15mBritish Airways
Deal found 17/11£1,276

Cheap flight deals from Southampton to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 20 marraskuu 2025.

Round-trip from

£483

One-way from

£454

Popular in

July

Cheapest in

September

Average price

£465
Virgin Atlantic
  • Virgin Atlantic
  • 22/12-29/12
  • 2 total stops
  • 69h 25m total
  • Southampton to San Francisco
Search Deals
British Airways
  • British Airways
  • 10/1
  • 2 total stops
  • 54h 20m total
  • Southampton to San Francisco
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (£63 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£11 potential savings vs. average return price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 20 marraskuu 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Southampton

Fly to

San Francisco

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ke 21/1

17:35-11:50

1 stop26h 15m

San Francisco

su 25/1

13:55-17:00

1 stop19h 05m

£500

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ma 22/12

18:05-11:50

1 stop25h 45m

San Francisco

ma 29/12

23:45-17:00

2 stops33h 15m

£502

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ke 21/1

09:25-23:25

2 stops22h 00m

San Francisco

su 25/1

07:00-08:50

2 stops17h 50m

£503

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

pe 5/12

08:40-11:50

1 stop35h 10m

San Francisco

ke 14/1

11:15-17:05

2 stops21h 50m

£555

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

la 6/12

09:25-11:50

1 stop34h 25m

San Francisco

ti 13/1

13:55-17:05

1 stop19h 10m

£555

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

to 4/12

08:50-11:50

1 stop35h 00m

San Francisco

ma 19/1

08:00-08:50

2 stops16h 50m

£555

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

to 4/12

08:50-11:50

1 stop35h 00m

San Francisco

ti 13/1

22:55-08:25

2 stops25h 30m

£555

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

to 4/12

18:05-11:50

1 stop25h 45m

San Francisco

su 18/1

13:55-17:05

1 stop19h 10m

£555

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

la 10/1

17:15-15:35

2 stops54h 20m

£454

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

ma 23/3

09:30-16:35

1 stop14h 05m

£473

Flights are sorted by cheapest return flights first.

Deals found on 18/11

Showing 1-10 of 15 results
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Best time to book a flight from Southampton to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to San Francisco

What is the cheapest month to book a flight from Southampton to San Francisco?

Currently, December is the cheapest month in which you can book a flight from Southampton to San Francisco (average of £346). Flying from Southampton to San Francisco in July is currently the most expensive (average of £468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Southampton to San Francisco?

    Delta and Virgin Atlantic can get you from Southampton to San Francisco in just under 22h. Your travel time can differ by up to 4h 15m. Southampton and San Francisco are separated by a distance of 5349 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Southampton to San Francisco that include hotel bookings?

    Yes. In addition to deals on Southampton to San Francisco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to San Francisco.

  • Can I find deals for business class flights from Southampton to San Francisco?

    Yes. Cheapflights offers flight deals from Southampton to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to San Francisco?

    Currently, December is the cheapest month in which you can book a flight from Southampton to San Francisco (average of £346). Flying from Southampton to San Francisco in July is currently the most expensive (average of £468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Newark
South San Francisco
San Bruno
Bodega Bay
Pacific Grove

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Southampton to San Francisco

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to San Francisco?

Cheapflights helps you search for flights from Southampton to San Francisco via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Southampton to San Francisco?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Southampton to San Francisco.

Can Cheapflights find flights from Southampton to San Francisco with no change fees?

Need flexible booking options for your flight to San Francisco from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Southampton to San Francisco become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to San Francisco from Southampton today and book when prices fit your budget.

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