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Cheap flights from Southampton to San Francisco from £349

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 30/9. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SFO
14 Jul — 21 Jul1
1 adult

Cheap flight deals from Southampton to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 9 July 2025.

Round-trip from

£566

One-way from

£349

Popular in

April

Cheapest in

February

Average price

£871
Virgin Atlantic
  • Virgin Atlantic
  • 17/8-24/8
  • 4 total stops
  • 73h 09m total
  • Southampton to San Francisco
30/9
  • 30/9
  • 3 total stops
  • 47h 04m total
  • Southampton to San Francisco
Highest demand for flights based on searches. 5% potential increase in price (£27 potential increase over avg. return price).
Cheapest flight prices on average. 5% potential price decrease (£26 potential savings vs. average return price).
Average for round-trip flights in July 2025

Find flight deals from Southampton to San Francisco

Cheapest flights from Southampton to San Francisco
Explore the most affordable flight options available from Southampton to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 July 2025.

Sun 17/817:35SOU - SFO
2 stops35h 54mVirgin Atlantic
Sun 24/811:35SFO - SOU
2 stops37h 15mVirgin Atlantic
Deal found 7/7£566
Mon 14/718:25SOU - SFO
2 stops29h 48mDelta
Wed 17/911:35SFO - SOU
2 stops21h 25mDelta
Deal found 7/7£580
Sun 17/817:35SOU - SFO
1 stop26h 10mKLM
Sun 24/813:45SFO - SOU
1 stop35h 05mKLM
Deal found 7/7£583
Fri 22/816:15SOU - SFO
1 stop29h 35mMultiple Airlines
Fri 29/822:17SFO - SOU
2 stops32h 03mMultiple Airlines
Deal found 8/7£752
Fri 22/809:40SOU - SFO
1 stop14h 10mAer Lingus
Fri 29/817:40SFO - SOU
1 stop14h 05mAer Lingus
Deal found 8/7£849

Cheapflights Fare Finder

Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 9 July 2025.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Southampton

Fly to

San Francisco

Route

Depart

Return

Price

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 17/8

17:35-21:29

2 stops35h 54m

San Francisco

Sun 24/8

11:35-08:50

2 stops37h 15m

£566

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 17/8

17:35-11:45

1 stop26h 10m

San Francisco

Sun 24/8

13:45-08:50

1 stop35h 05m

£583

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Wed 6/8

09:20-00:34

2 stops23h 14m

San Francisco

Mon 25/8

06:15-08:50

2 stops18h 35m

£629

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 22/8

16:15-13:50

1 stop29h 35m

San Francisco

Fri 29/8

22:17-14:20

2 stops32h 03m

£752

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 22/8

09:40-15:50

1 stop14h 10m

San Francisco

Fri 29/8

17:40-15:45

1 stop14h 05m

£849

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 30/9

08:55-23:59

3 stops47h 04m

£349

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 30/9

09:20-11:45

1 stop34h 25m

£1,088

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 31/8

18:25-11:45

1 stop25h 20m

£1,123

Flights are sorted by cheapest return flights first.

Deals found on 8/7

Best time to book a flight from Southampton to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to San Francisco

What is the cheapest month to book a flight from Southampton to San Francisco?

Currently, February is the cheapest month in which you can book a flight from Southampton to San Francisco (average of £538). Flying from Southampton to San Francisco in July is currently the most expensive (average of £803). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated 9 July 2025.
Get a feel of what it's like to fly with Delta, KLM, andVirgin Atlantic from Southampton to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very Good

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Southampton to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Southampton to San Francisco round-trip?

    Currently priced at £566, Virgin Atlantic will fly you from Southampton to San Francisco and back. In addition to Virgin Atlantic, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from KLM and Delta - these airlines can fly you to your destination from £583 and £629, respectively. Virgin Atlantic is 15% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Southampton to San Francisco that include hotel bookings?

    Yes. In addition to deals on Southampton to San Francisco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to San Francisco.

  • Can I find deals for business class flights from Southampton to San Francisco?

    Yes. Cheapflights offers flight deals from Southampton to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to San Francisco?

    Currently, February is the cheapest month in which you can book a flight from Southampton to San Francisco (average of £538). Flying from Southampton to San Francisco in July is currently the most expensive (average of £803). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Southampton?

Book flights to Southampton if you plan to visit one of these locations
Santa Cruz
Vallejo
Newark
South San Francisco
Bodega Bay
Pacific Grove
Union City

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Alternative routes for Southampton to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Fly with Cheapflights

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How does Cheapflights help users find flights from Southampton to San Francisco?

Cheapflights helps you search for flights from Southampton to San Francisco via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Southampton to San Francisco?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Southampton to San Francisco.

Can Cheapflights find flights from Southampton to San Francisco with no change fees?

Need flexible booking options for your flight to San Francisco from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Southampton to San Francisco become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to San Francisco from Southampton today and book when prices fit your budget.

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