How long is the flight from Manchester to South America?

A quick flight from Manchester to South America can take about 21h 55m. KLM provides one of the quickest options available for as low as £707. The distance between Manchester and South America is about 4488 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

What are the cheapest airlines to fly from Manchester to South America one-way?

The cheapest airline one-way is TAP AIR PORTUGAL, with whom users have recently found tickets for as low as £436. However, be on the lookout for offers from Lufthansa and Air France, as they are both options that can get you from Manchester to South America for a low price.

In terms of precipitation, rainfall in South America ranges from 20.0 - 240.0 inches per month. January is typically the wettest month, when rainfall can reach 240.0 mm. July is typically the driest time to visit South America when rainfall is around 20.0 mm.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 23.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 17.0 C).

What are the most popular routes from Manchester to South America?

Most travelers choose Manchester - Sao Paulo Guarulhos Intl, Manchester - Buenos Aires Ministro Pistarini or Manchester - Buenos Aires Jorge Newbery when deciding on the best route from Manchester to South America.

What are the most popular airlines that fly from Manchester to South America?

When booking a flight from Manchester to South America, you may want to consider flying on Lufthansa, British Airways or KLM as they are the most popular for this route.

What is the cheapest time of day to fly from MAN to SA?

When flying from Manchester to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly from for flights from Manchester to South America?

For a flight from Manchester to South America, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

Can I find deals for flights from Manchester to South America that include hotel bookings?

Yes. In addition to deals on Manchester to South America flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Manchester to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South America.

Can I find deals for business class flights from Manchester to South America?

Yes. Cheapflights offers flight deals from Manchester to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£356+ Cheap Flights from Manchester to South America

Cheap flight deals from Manchester to South America

Enter your travel dates to find the best prices.

Cheapest

Best

Last-minute

One-way

Cheapest flights from Manchester to South America
Explore the most affordable flight options available from Manchester to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 October 2026.

Sun 8/1105:55 -

2 stops41h 00m

Thu 26/1116:20 -

1 stop15h 20m

Deal found 2/10£564

Wed 18/1106:00 -

2 stops19h 25m

Wed 25/1116:20 -

1 stop15h 20m

Deal found 4/10£579

Mon 16/1121:35 -

2 stops49h 35m

Mon 30/1122:05 -

1 stop33h 35m

Deal found 5/10£580

Sun 15/1108:45 -

2 stops38h 10m

Sat 21/1101:30 -

1 stop30h 10m

Deal found 1/10£583

Thu 19/1106:05 -

2 stops20h 50m

Tue 8/1216:20 -

1 stop15h 20m

Deal found 2/10£587

Sat 14/1116:10 -

2 stops55h 00m

Mon 23/1116:35 -

1 stop15h 05m

Deal found 5/10£589

Thu 19/1106:15 -

2 stops37h 05m

Wed 2/1216:35 -

1 stop15h 05m

Deal found 2/10£595

Tue 17/1106:00 -

2 stops41h 10m

Tue 24/1116:35 -

1 stop15h 05m

Deal found 3/10£598

Fri 20/1122:25 -

2 stops28h 30m

Thu 3/1201:30 -

1 stop30h 10m

Deal found 3/10£601

Thu 12/1106:05 -

1 stop19h 00m

Tue 24/1116:20 -

1 stop15h 20m

Deal found 2/10£619

Wed 18/1108:15 -

2 stops19h 45m

Wed 25/1116:35 -

1 stop15h 05m

Deal found 4/10£620

Sun 15/1120:45 -

3 stops28h 00m

Sun 22/1122:05 -

1 stop33h 35m

Deal found 1/10£632

Best flights from Manchester to South America
Discover carefully curated flight deals from Manchester to South America that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 October 2026.

Mon 16/1116:25 -

1 stop18h 25m

Sun 29/1111:35 -

1 stop15h 40m

Deal found 1/10£699

Fri 20/1120:40 -

1 stop21h 55m

Sat 28/1115:55 -

2 stops17h 00m

Deal found 3/10£707

Wed 18/1106:10 -

3 stops28h 10m

Wed 9/1209:00 -

2 stops18h 45m

Deal found 3/10£756

Tue 10/1117:00 -

2 stops47h 15m

Mon 30/1113:55 -

2 stops29h 55m

Deal found 6/10£792

Thu 5/1105:05 -

2 stops23h 21m

Thu 12/1107:00 -

2 stops21h 15m

Deal found 6/10£838

Mon 8/210:45 -

1 stop32h 00m

Fri 12/215:15 -

2 stops37h 25m

Deal found 5/10£855

Wed 24/211:25 -

2 stops38h 20m

Wed 24/316:35 -

1 stop15h 05m

Deal found 5/10£897

Sun 17/114:55 -

1 stop22h 00m

Sun 31/123:45 -

2 stops30h 55m

Deal found 3/10£971

Thu 12/1106:10 -

2 stops21h 25m

Mon 16/1111:05 -

2 stops28h 30m

Deal found 4/10£1,020

Thu 19/1106:00 -

2 stops30h 20m

Thu 26/1122:05 -

2 stops34h 25m

Deal found 4/10£1,222

Fri 16/1014:55 -

1 stop21h 55m

Thu 12/1112:05 -

1 stop25h 00m

Deal found 6/10£1,247

Thu 12/1118:30 -

3 stops31h 40m

Mon 16/1118:25 -

3 stops34h 55m

Deal found 3/10£1,266

Fri 16/1018:40 -

2 stops19h 00m

Mon 26/1015:15 -

2 stops38h 05m

Deal found 1/10£1,287

Fri 13/1113:40 -

1 stop28h 55m

Sat 21/1115:55 -

2 stops20h 40m

Deal found 6/10£707

Sun 7/309:05 -

1 stop15h 15m

Mon 15/323:15 -

1 stop18h 30m

Deal found 3/10£725

Fri 13/1120:40 -

1 stop26h 30m

Sun 22/1120:10 -

1 stop18h 50m

Deal found 6/10£728

Thu 21/111:30 -

2 stops42h 35m

Mon 25/109:30 -

2 stops19h 50m

Deal found 5/10£829

Mon 15/211:55 -

2 stops22h 15m

Tue 23/207:00 -

2 stops23h 20m

Deal found 1/10£849

Sun 28/205:50 -

2 stops21h 15m

Mon 15/319:20 -

1 stop21h 10m

Deal found 2/10£794

Tue 24/1112:15 -

2 stops23h 35m

Wed 25/1117:45 -

1 stop26h 00m

Deal found 3/10£899

Wed 18/1120:40 -

2 stops25h 15m

Wed 2/1220:10 -

1 stop15h 25m

Deal found 3/10£782

Thu 19/1107:25 -

3 stops29h 20m

Thu 26/1105:00 -

2 stops26h 40m

Deal found 5/10£796

Fri 19/214:55 -

1 stop21h 40m

Wed 24/321:15 -

1 stop34h 35m

Deal found 3/10£971

Thu 12/1111:25 -

1 stop32h 20m

Mon 16/1118:15 -

1 stop13h 25m

Deal found 2/10£989

Tue 10/1109:40 -

2 stops24h 35m

Wed 25/1112:05 -

1 stop20h 50m

Deal found 4/10£908

Tue 2/210:45 -

1 stop20h 35m

Sat 20/217:10 -

1 stop37h 30m

Deal found 2/10£1,015

Sat 9/111:30 -

2 stops42h 35m

Mon 18/109:30 -

2 stops19h 50m

Deal found 4/10£951

Fri 30/1014:55 -

1 stop28h 30m

Sun 22/1121:35 -

1 stop18h 55m

Deal found 1/10£809

Sun 17/109:40 -

1 stop23h 20m

Sun 31/116:10 -

1 stop20h 25m

Deal found 3/10£922

Wed 18/1105:50 -

1 stop13h 40m

Wed 25/1121:35 -

2 stops19h 30m

Deal found 4/10£857

Find flight deals from Manchester to South America

Round-trip from	£564
One-way from	£356
Popular in	July
Cheapest in	March
Average price	£834

TAP AIR PORTUGAL
8/11-26/11
3 total stops
56h 20m total
Manchester to South America

Search Deals

16/11-31/12
3 total stops
51h 00m total
Manchester to South America

Search Deals

Highest demand for flights based on searches. 13% potential increase in price (£95 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease (£18 potential savings vs. average return price).

Search Deals

Average for round-trip flights in October 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterQuito

MAN Manchester - UIO Quito Mariscal Sucr

MANUIO

Manchester

Wed 10/3

10:05-06:55

2 stops25h 50m

Quito Mariscal Sucr

Wed 31/12

00:00-06:00

Nonstop0h 00m

£393

ManchesterBuenos Aires

MAN Manchester - EZE Buenos Aires Ministro Pistarini

MANEZE

Manchester

Mon 2/11

19:30-12:44

3 stops44h 14m

Buenos Aires Ministro Pistarini

Wed 31/12

00:00-04:00

Nonstop0h 00m

£424

ManchesterLima

MAN Manchester - LIM Lima J Chavez Intl

MANLIM

Manchester

Wed 11/11

08:20-01:00

3 stops45h 40m

Lima J Chavez Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£440

ManchesterRio de Janeiro

MAN Manchester - GIG Rio de Janeiro–Galeão Intl

MANGIG

Manchester

Wed 31/3

06:00-19:45

1 stop17h 45m

Rio de Janeiro–Galeão Intl

Wed 31/12

00:00-04:00

Nonstop0h 00m

£467

ManchesterRio de Janeiro

MAN Manchester - GIG Rio de Janeiro–Galeão Intl

MANGIG

Manchester

Wed 31/3

16:05-17:35

2 stops29h 30m

Rio de Janeiro–Galeão Intl

Wed 31/12

00:00-04:00

Nonstop0h 00m

£480

ManchesterSantiago

MAN Manchester - SCL Santiago Arturo Merino Benitez

MANSCL

Manchester

Tue 9/3

13:45-17:10

2 stops30h 25m

Santiago Arturo Merino Benitez

Wed 31/12

00:00-04:00

Nonstop0h 00m

£483

ManchesterRio de Janeiro

MAN Manchester - GIG Rio de Janeiro–Galeão Intl

MANGIG

Manchester

Fri 15/1

19:15-00:25

2 stops32h 10m

Rio de Janeiro–Galeão Intl

Wed 31/12

00:00-04:00

Nonstop0h 00m

£489

ManchesterQuito

MAN Manchester - UIO Quito Mariscal Sucr

MANUIO

Manchester

Wed 4/11

16:50-01:10

2 stops37h 20m

Quito Mariscal Sucr

Wed 31/12

00:00-06:00

Nonstop0h 00m

£495

ManchesterGeorgetown

MAN Manchester - GEO Georgetown Cheddi Jagan Intl

MANGEO

Manchester

Sun 15/11

18:50-17:45

3 stops50h 55m

Georgetown Cheddi Jagan Intl

Wed 31/12

00:00-04:45

Nonstop0h 00m

£497

ManchesterBuenos Aires

MAN Manchester - EZE Buenos Aires Ministro Pistarini

MANEZE

Manchester

Thu 31/12

17:25-04:40

2 stops38h 15m

Buenos Aires Ministro Pistarini

Wed 31/12

00:00-04:00

Nonstop0h 00m

£505

Flights are sorted by cheapest return flights first.

Deals found on 5/10

Showing 1-10 of 60 resultsSorted by cheapest first

...

Best time to book a flight from Manchester to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Manchester with our price prediction graph.

MAN-BOG

MAN-GIG

MAN-UIO

MAN-GRU

MAN-EZE

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South America

MAN-0SA

MAN-BOG

MAN-GIG

MAN-UIO

MAN-GRU

What is the cheapest month to book a flight from Manchester to South America?

Currently, March is the cheapest month in which you can book a flight from Manchester to South America (average of £800). Flying from Manchester to South America in December is currently the most expensive (average of £1,089). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from Manchester to South America?

Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to South America. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Reviews of airlines servicing South America

Read reviews from past customers who have flown with KLM,Air France, andTAP AIR PORTUGAL from Manchester to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

KLM

7.8

Good

1,579 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

KLM

7.8

Good

1,579 reviews

KLM

7.8

Good

1,579 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Air France

7.5

Good

1,649 reviews

KLM

7.8

Good

1,579 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

TAP AIR PORTUGAL

7.2

Good

2,383 reviews

KLM

7.8

Good

1,579 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Lufthansa

6.8

Okay

8,259 reviews

KLM

7.8

Good

1,579 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

British Airways

6.7

Okay

8,245 reviews

KLM

7.8

Good

1,579 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

What airport do you fly from for flights from Manchester to South America?
For a flight from Manchester to South America, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.
How long is the flight from Manchester to South America?
A quick flight from Manchester to South America can take about 21h 55m. KLM provides one of the quickest options available for as low as £707. The distance between Manchester and South America is about 4488 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines to fly from Manchester to South America one-way?
The cheapest airline one-way is TAP AIR PORTUGAL, with whom users have recently found tickets for as low as £436. However, be on the lookout for offers from Lufthansa and Air France, as they are both options that can get you from Manchester to South America for a low price.
What are the most popular routes from Manchester to South America?
Most travelers choose Manchester - Sao Paulo Guarulhos Intl, Manchester - Buenos Aires Ministro Pistarini or Manchester - Buenos Aires Jorge Newbery when deciding on the best route from Manchester to South America.
Can I find deals for flights from Manchester to South America that include hotel bookings?
Yes. In addition to deals on Manchester to South America flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Manchester to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South America.
Can I find deals for business class flights from Manchester to South America?
Yes. Cheapflights offers flight deals from Manchester to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Manchester to South America?
Currently, March is the cheapest month in which you can book a flight from Manchester to South America (average of £800). Flying from Manchester to South America in December is currently the most expensive (average of £1,089). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes

Complete your trip

Direct flights to

Flights by cabin class

Other flight options

Popular flights

Top countries

Top destinations

Alternative routes for Manchester to South America

Heathrow to Suvarnabhumi flights

Gatwick to Suvarnabhumi flights

Heathrow to Málaga flights

Gatwick to Charles de Gaulle flights

Luton to Charles de Gaulle flights

London City to Charles de Gaulle flights

Heathrow to Charles de Gaulle flights

Stansted to Suvarnabhumi flights

Stansted to Beauvais-Tille flights

Gatwick to Beauvais-Tille flights

Gatwick to Málaga flights

Luton to Málaga flights

Heathrow to John F Kennedy Intl flights

Heathrow to Sydney flights

Heathrow to New Delhi flights

Heathrow to Newark flights

Stansted to Málaga flights

Gatwick to Orly flights

London City to Suvarnabhumi flights

Southend to Charles de Gaulle flights

Heathrow to Granada flights

Heathrow to Haneda flights

Luton to Beauvais-Tille flights

Gatwick to Granada flights

Heathrow to Dubai flights

Stansted to Orly flights

London City to Orly flights

Gatwick to Istanbul flights

Heathrow to Lagos flights

Gatwick to Dubai flights

Stansted to Dubai flights

Heathrow to Mumbai flights

Heathrow to Don Mueang Intl flights

Stansted to Edinburgh flights

Gatwick to Don Mueang Intl flights

Heathrow to Hong Kong flights

Gatwick to Edinburgh flights

Luton to Edinburgh flights

Stansted to Istanbul flights

Gatwick to Lagos flights

Gatwick to Amsterdam flights

Luton to Orly flights

Heathrow to LaGuardia flights

Luton to Suvarnabhumi flights

Gatwick to Sydney flights

Stansted to John F Kennedy Intl flights

Heathrow to Kuala Lumpur Intl flights

Heathrow to Istanbul flights

Luton to Amsterdam flights

Heathrow to Narita flights

Top 10 airlines flying from Manchester to South America

Airline	Cheapest	Average	Flexibility	On-time
Lufthansa	Cheapest£525	Average£953	FlexibilityNo cancel fee	On-time76%	Search Lufthansa flights
SWISS	Cheapest£598	Average£786	FlexibilityNo cancel fee	On-time79%	Search SWISS flights
Iberia	Cheapest£617	Average£904	FlexibilityNo cancel fee	On-time77%	Search Iberia flights
KLM	Cheapest£622	Average£1,052	FlexibilityNo cancel fee	On-time75%	Search KLM flights
British Airways	Cheapest£655	Average£940	FlexibilityNo cancel fee	On-time70%	Search British Airways flights
Air France	Cheapest£663	Average£1,001	FlexibilityNo cancel fee	On-time77%	Search Air France flights
Air Canada	Cheapest£667	Average£721	FlexibilityNo cancel fee	On-time67%	Search Air Canada flights
TAP AIR PORTUGAL	Cheapest£683	Average£977	FlexibilityNo cancel fee	On-timeN/A	Search TAP AIR PORTUGAL flights
Virgin Atlantic	Cheapest£691	Average£754	FlexibilityNo cancel fee	On-time72%	Search Virgin Atlantic flights
Turkish Airlines	Cheapest£734	Average£797	FlexibilityNo cancel fee	On-time77%	Search Turkish Airlines flights

Fly with Cheapflights

How does Cheapflights help users find flights from Manchester to South America?

Deals for Manchester to South America flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South America?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to South America from Manchester.

Can Cheapflights find flights from Manchester to South America with no change fees?

Need flexible booking options for your flight to South America from Manchester? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South America become cheaper?

Of course! You can now track prices for flights from Manchester to South America and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

Cheap flights from Manchester to South America from £356

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/11. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Manchester to South America

Cheapest flights from Manchester to South AmericaExplore the most affordable flight options available from Manchester to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 October 2026.

Explore the most affordable flight options available from Manchester to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 October 2026.

Best flights from Manchester to South AmericaDiscover carefully curated flight deals from Manchester to South America that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 October 2026.

Discover carefully curated flight deals from Manchester to South America that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 October 2026.

Last-minute flights from Manchester to South AmericaDiscover last-minute flight deals from Manchester to South America. Data last updated 6 October 2026 and is based on user searches.

Discover last-minute flight deals from Manchester to South America. Data last updated 6 October 2026 and is based on user searches.

One-way flights from Manchester to South AmericaSearch for one-way flight options from Manchester to South America. Find affordable one-way fares based on user searches. Data last updated 6 October 2026.

Search for one-way flight options from Manchester to South America. Find affordable one-way fares based on user searches. Data last updated 6 October 2026.

Find flight deals from Manchester to South America

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to South America that are best for you.

Best time to book a flight from Manchester to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Manchester with our price prediction graph.

Cheapflights Insights

What is the cheapest month to book a flight from Manchester to South America?

How far ahead should I book a flight from Manchester to South America?

Booking 90 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to South America. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Reviews of airlines servicing South America

Read reviews from past customers who have flown with KLM,Air France, andTAP AIR PORTUGAL from Manchester to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Manchester to South America?

How long is the flight from Manchester to South America?

What are the cheapest airlines to fly from Manchester to South America one-way?

What are the most popular routes from Manchester to South America?

Can I find deals for flights from Manchester to South America that include hotel bookings?

How can I find direct flights from Manchester to South America?

Can I find deals for business class flights from Manchester to South America?

What is the cheapest month to book a flight from Manchester to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to South America

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to South America by adding a car hire and/or hotel booking to your travel itinerary.

Direct flights to

Book a non-stop flight to one of these other cities located in .

Search flights from Manchester to South America by cabin class

Find flights from Manchester to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Manchester and South America flights

Browse other Manchester and South America flight options. Last updated on 6 October 2026.

Popular flight searches

Check out other popular destinations found by fellow travellers in 2026

Fly to South America countries

Consider these flights travelling to countries located in South America.

Manchester to South America flights

Consider these flights travelling from Manchester to South America.

Top 10 airlines flying from Manchester to South America

Fly with Cheapflights

How does Cheapflights help users find flights from Manchester to South America?

Why should you use Cheapflights to find cheap flight tickets from Manchester to South America?

Can Cheapflights find flights from Manchester to South America with no change fees?

Can Cheapflights notify me if prices for flights from Manchester to South America become cheaper?

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Manchester to South America
Explore the most affordable flight options available from Manchester to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 October 2026.

Best flights from Manchester to South America
Discover carefully curated flight deals from Manchester to South America that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 October 2026.

Last-minute flights from Manchester to South America
Discover last-minute flight deals from Manchester to South America. Data last updated 6 October 2026 and is based on user searches.

One-way flights from Manchester to South America
Search for one-way flight options from Manchester to South America. Find affordable one-way fares based on user searches. Data last updated 6 October 2026.