How long is the flight from Manchester to South America?

A quick flight from Manchester to South America can take about 18h 25m. Air Canada provides one of the quickest options available for as low as £763. The distance between Manchester and South America is about 5211 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

What are the cheapest airlines to fly from Manchester to South America one-way?

The cheapest airline one-way is TAP AIR PORTUGAL, with whom users have recently found tickets for as low as £424. However, be on the lookout for offers from Lufthansa and Air France, as they are both options that can get you from Manchester to South America for a low price.

In terms of precipitation, rainfall in South America ranges from 20.0 - 240.0 inches per month. January is typically the wettest month, when rainfall can reach 240.0 mm. July is typically the driest time to visit South America when rainfall is around 20.0 mm.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 23.0 C. Travellers hoping to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 17.0 C).

What are the most popular routes from Manchester to South America?

Most travelers choose Manchester - Sao Paulo Guarulhos Intl, Manchester - Sao Paulo Viracopos or Manchester - Rio de Janeiro–Galeão Intl when deciding on the best route from Manchester to South America.

What are the most popular airlines that fly from Manchester to South America?

When booking a flight from Manchester to South America, you may want to consider flying on Lufthansa, British Airways or KLM as they are the most popular for this route.

What is the cheapest time of day to fly from MAN to SA?

When flying from Manchester to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly from for flights from Manchester to South America?

For a flight from Manchester to South America, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

Can I find deals for flights from Manchester to South America that include hotel bookings?

Yes. In addition to deals on Manchester to South America flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Manchester to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South America.

Can I find deals for business class flights from Manchester to South America?

Yes. Cheapflights offers flight deals from Manchester to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£333+ Cheap Flights from Manchester to South America

Cheap flight deals from Manchester to South America

Enter your travel dates to find the best prices.

Cheapest

Best

Last-minute

One-way

Cheapest flights from Manchester to South America
Explore the most affordable flight options available from Manchester to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2026.

Mon 9/1114:15 -

1 stop21h 20m

Sun 22/1123:10 -

1 stop32h 55m

Deal found 14/9£594

Sat 31/1020:55 -

1 stop25h 15m

Sat 14/1119:10 -

1 stop22h 55m

Deal found 16/9£607

Mon 16/1114:15 -

1 stop21h 10m

Mon 30/1111:40 -

1 stop20h 25m

Deal found 16/9£611

Mon 9/1114:15 -

1 stop21h 20m

Sun 22/1121:05 -

2 stops19h 30m

Deal found 15/9£650

Mon 16/1114:15 -

1 stop21h 10m

Mon 30/1111:40 -

2 stops19h 05m

Deal found 16/9£651

Wed 18/1114:55 -

2 stops20h 10m

Wed 2/1212:05 -

1 stop20h 50m

Deal found 16/9£657

Sun 8/1117:45 -

2 stops27h 55m

Thu 26/1119:25 -

1 stop14h 50m

Deal found 16/9£679

Sat 21/1117:00 -

2 stops28h 40m

Sat 5/1215:45 -

2 stops22h 15m

Deal found 15/9£689

Fri 6/1117:00 -

2 stops28h 40m

Wed 18/1122:25 -

1 stop14h 50m

Deal found 13/9£689

Mon 14/905:50 -

1 stop17h 50m

Mon 28/922:00 -

1 stop20h 20m

Deal found 12/9£699

Fri 13/1106:40 -

2 stops26h 50m

Thu 26/1115:05 -

2 stops25h 00m

Deal found 15/9£700

Wed 18/1109:05 -

1 stop15h 20m

Wed 9/1221:10 -

2 stops15h 45m

Deal found 12/9£700

Best flights from Manchester to South America
Discover carefully curated flight deals from Manchester to South America that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 17 September 2026.

Tue 12/111:30 -

2 stops22h 50m

Wed 20/109:00 -

2 stops19h 00m

Deal found 14/9£715

Tue 27/1020:40 -

2 stops25h 15m

Tue 3/1119:20 -

1 stop21h 10m

Deal found 12/9£744

Sat 20/206:00 -

1 stop18h 25m

Tue 16/323:15 -

1 stop18h 30m

Deal found 15/9£763

Tue 27/1020:40 -

2 stops25h 15m

Tue 3/1119:20 -

2 stops19h 40m

Deal found 12/9£767

Sun 17/109:40 -

1 stop23h 20m

Sun 31/116:10 -

1 stop16h 00m

Deal found 16/9£831

Wed 24/211:25 -

2 stops38h 20m

Wed 24/316:35 -

1 stop15h 05m

Deal found 14/9£831

Mon 8/210:45 -

1 stop32h 00m

Fri 12/215:15 -

2 stops37h 25m

Deal found 14/9£860

Mon 15/306:00 -

2 stops29h 55m

Thu 8/409:45 -

2 stops44h 05m

Deal found 14/9£967

Sun 25/1018:30 -

2 stops24h 30m

Fri 6/1101:30 -

2 stops27h 50m

Deal found 15/9£1,016

Sun 8/1114:00 -

2 stops29h 00m

Wed 2/1202:05 -

2 stops32h 10m

Deal found 15/9£1,107

Wed 17/213:35 -

1 stop24h 35m

Sun 21/222:45 -

1 stop35h 20m

Deal found 16/9£1,160

Fri 4/1206:00 -

2 stops19h 20m

Mon 28/1216:55 -

2 stops22h 45m

Deal found 12/9£1,306

Sat 20/218:45 -

2 stops29h 40m

Mon 15/323:15 -

1 stop18h 30m

Deal found 15/9£753

Thu 3/1214:55 -

1 stop28h 30m

Thu 17/1216:05 -

2 stops19h 30m

Deal found 16/9£851

Fri 30/1014:55 -

1 stop28h 30m

Fri 20/1121:35 -

1 stop13h 30m

Deal found 13/9£778

Wed 17/209:20 -

1 stop24h 30m

Thu 25/218:00 -

1 stop17h 15m

Deal found 15/9£867

Sun 14/211:25 -

2 stops32h 55m

Sat 6/303:15 -

2 stops52h 25m

Deal found 14/9£918

Sat 24/1011:10 -

2 stops22h 10m

Tue 10/1115:45 -

2 stops21h 30m

Deal found 15/9£944

Thu 29/1014:35 -

1 stop33h 50m

Thu 5/1121:05 -

2 stops16h 55m

Deal found 14/9£788

Mon 22/214:00 -

1 stop28h 45m

Fri 19/315:15 -

2 stops37h 25m

Deal found 15/9£956

Wed 10/306:00 -

2 stops29h 55m

Thu 18/309:45 -

2 stops46h 45m

Deal found 16/9£985

Tue 29/1220:40 -

1 stop25h 10m

Mon 1/220:59 -

1 stop22h 06m

Deal found 13/9£915

Sun 11/1018:30 -

2 stops25h 55m

Thu 15/1001:45 -

2 stops26h 45m

Deal found 12/9£1,017

Sun 4/1007:00 -

2 stops21h 25m

Wed 4/1107:00 -

2 stops28h 20m

Deal found 14/9£929

Mon 15/311:25 -

1 stop22h 25m

Sat 10/415:30 -

1 stop14h 35m

Deal found 14/9£957

Wed 18/1120:40 -

1 stop22h 50m

Wed 9/1221:35 -

1 stop18h 55m

Deal found 13/9£802

Wed 10/306:00 -

2 stops29h 55m

Wed 17/312:45 -

2 stops67h 45m

Deal found 14/9£988

Thu 18/216:55 -

3 stops37h 25m

Sun 28/213:20 -

2 stops39h 20m

Deal found 14/9£1,018

Mon 15/311:55 -

1 stop21h 05m

Fri 9/419:20 -

2 stops21h 45m

Deal found 14/9£929

Tue 29/1211:25 -

1 stop15h 30m

Sun 31/101:30 -

1 stop30h 10m

Deal found 16/9£966

Find flight deals from Manchester to South America

Round-trip from	£594
One-way from	£333
Popular in	July
Cheapest in	March
Average price	£787

Iberia
9/11-22/11
2 total stops
54h 15m total
Manchester to South America

Search Deals

22/11-31/12
1 total stop
37h 25m total
Manchester to South America

Search Deals

Highest demand for flights based on searches. 13% potential increase in price (£96 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease (£17 potential savings vs. average return price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterSao Paulo

MAN Manchester - VCP Sao Paulo Viracopos

MANVCP

Manchester

Sat 21/11

05:45-19:25

1 stop16h 40m

Sao Paulo Viracopos

Wed 31/12

00:00-04:00

Nonstop0h 00m

£336

ManchesterSao Paulo

MAN Manchester - VCP Sao Paulo Viracopos

MANVCP

Manchester

Mon 23/11

05:55-01:20

2 stops22h 25m

Sao Paulo Viracopos

Wed 31/12

00:00-04:00

Nonstop0h 00m

£347

ManchesterSao Paulo

MAN Manchester - VCP Sao Paulo Viracopos

MANVCP

Manchester

Tue 24/11

11:20-16:40

2 stops56h 20m

Sao Paulo Viracopos

Wed 31/12

00:00-04:00

Nonstop0h 00m

£364

ManchesterBogotá

MAN Manchester - BOG Bogotá El Dorado

MANBOG

Manchester

Tue 9/2

15:55-23:45

2 stops36h 50m

Bogotá El Dorado

Wed 31/12

00:00-06:00

Nonstop0h 00m

£381

ManchesterSao Paulo

MAN Manchester - VCP Sao Paulo Viracopos

MANVCP

Manchester

Wed 25/11

08:05-16:40

1 stop35h 35m

Sao Paulo Viracopos

Wed 31/12

00:00-04:00

Nonstop0h 00m

£415

ManchesterSao Paulo

MAN Manchester - GRU Sao Paulo Guarulhos Intl

MANGRU

Manchester

Sat 21/11

20:55-18:40

2 stops24h 45m

Sao Paulo Guarulhos Intl

Wed 31/12

00:00-04:00

Nonstop0h 00m

£416

ManchesterLima

MAN Manchester - LIM Lima J Chavez Intl

MANLIM

Manchester

Sat 14/11

21:00-05:50

2 stops37h 50m

Lima J Chavez Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£425

ManchesterSao Paulo

MAN Manchester - GRU Sao Paulo Guarulhos Intl

MANGRU

Manchester

Mon 25/1

16:05-22:25

2 stops33h 20m

Sao Paulo Guarulhos Intl

Wed 31/12

00:00-04:00

Nonstop0h 00m

£425

ManchesterLima

MAN Manchester - LIM Lima J Chavez Intl

MANLIM

Manchester

Sat 16/1

21:00-05:50

2 stops37h 50m

Lima J Chavez Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£426

ManchesterSao Paulo

MAN Manchester - GRU Sao Paulo Guarulhos Intl

MANGRU

Manchester

Fri 20/11

17:05-22:25

1 stop32h 20m

Sao Paulo Guarulhos Intl

Wed 31/12

00:00-04:00

Nonstop0h 00m

£520

Flights are sorted by cheapest return flights first.

Deals found on 13/9

Showing 1-10 of 60 resultsSorted by cheapest first

...

Best time to book a flight from Manchester to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Manchester with our price prediction graph.

MAN-VCP

MAN-GRU

MAN-GIG

MAN-AEP

MAN-SCL

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South America

MAN-0SA

MAN-VCP

MAN-GRU

MAN-GIG

MAN-AEP

What is the cheapest month to book a flight from Manchester to South America?

Currently, March is the cheapest month in which you can book a flight from Manchester to South America (average of £783). Flying from Manchester to South America in July is currently the most expensive (average of £1,066). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How far ahead should I book a flight from Manchester to South America?

Booking 82 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to South America. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Reviews of airlines servicing South America

Read reviews from past customers who have flown with KLM,Air France, andTAP AIR PORTUGAL from Manchester to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

KLM

7.8

Good

1,578 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

KLM

7.8

Good

1,578 reviews

KLM

7.8

Good

1,578 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Air France

7.5

Good

1,650 reviews

KLM

7.8

Good

1,578 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

TAP AIR PORTUGAL

7.2

Good

2,385 reviews

KLM

7.8

Good

1,578 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Lufthansa

6.8

Okay

8,229 reviews

KLM

7.8

Good

1,578 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

British Airways

6.7

Okay

8,228 reviews

KLM

7.8

Good

1,578 reviews

Check prices

Reviews

1 / 20

10.0

Excellent

Snapyou,Jan 2026

TPA - LHR

Flight operated by Virgin Atlantic - usual high standard service by Virgin.

Related info for your journey

What airport do you fly from for flights from Manchester to South America?
For a flight from Manchester to South America, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.
How long is the flight from Manchester to South America?
A quick flight from Manchester to South America can take about 18h 25m. Air Canada provides one of the quickest options available for as low as £763. The distance between Manchester and South America is about 5211 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines to fly from Manchester to South America one-way?
The cheapest airline one-way is TAP AIR PORTUGAL, with whom users have recently found tickets for as low as £424. However, be on the lookout for offers from Lufthansa and Air France, as they are both options that can get you from Manchester to South America for a low price.
What are the most popular routes from Manchester to South America?
Most travelers choose Manchester - Sao Paulo Guarulhos Intl, Manchester - Sao Paulo Viracopos or Manchester - Rio de Janeiro–Galeão Intl when deciding on the best route from Manchester to South America.
Can I find deals for flights from Manchester to South America that include hotel bookings?
Yes. In addition to deals on Manchester to South America flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Manchester to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South America.
Can I find deals for business class flights from Manchester to South America?
Yes. Cheapflights offers flight deals from Manchester to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Manchester to South America?
Currently, March is the cheapest month in which you can book a flight from Manchester to South America (average of £783). Flying from Manchester to South America in July is currently the most expensive (average of £1,066). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes

Complete your trip

Direct flights to

Flights by cabin class

Other flight options

Popular flights

Top countries

Top destinations

Alternative routes for Manchester to South America

Heathrow to Suvarnabhumi flights

Gatwick to Suvarnabhumi flights

Stansted to Suvarnabhumi flights

Heathrow to John F Kennedy Intl flights

London City to Suvarnabhumi flights

Heathrow to Newark flights

Heathrow to Sydney flights

Heathrow to Haneda flights

Heathrow to New Delhi flights

Heathrow to Dubai flights

Gatwick to Dubai flights

Stansted to Dubai flights

Heathrow to Don Mueang Intl flights

Luton to Edinburgh flights

Stansted to Edinburgh flights

Heathrow to Mumbai flights

Heathrow to Lagos flights

Gatwick to Edinburgh flights

Gatwick to Istanbul flights

Gatwick to John F Kennedy Intl flights

Stansted to Istanbul flights

Luton to Suvarnabhumi flights

Heathrow to LaGuardia flights

Heathrow to Istanbul flights

Heathrow to Hong Kong flights

Gatwick to Don Mueang Intl flights

Stansted to John F Kennedy Intl flights

Luton to Amsterdam flights

London City to John F Kennedy Intl flights

Gatwick to Newark flights

Stansted to Amsterdam flights

Heathrow to Amsterdam flights

Heathrow to Narita flights

Gatwick to Sydney flights

Heathrow to Edinburgh flights

Manchester to Suvarnabhumi flights

London City to Amsterdam flights

Heathrow to Colombo flights

Gatwick to Amsterdam flights

Heathrow to Leonardo da Vinci/Fiumicino flights

Heathrow to Kuala Lumpur Intl flights

Gatwick to Leonardo da Vinci/Fiumicino flights

Gatwick to Charles de Gaulle flights

Gatwick to Haneda flights

Heathrow to Jeddah flights

London City to Edinburgh flights

Gatwick to Narita flights

Luton to Charles de Gaulle flights

London City to Charles de Gaulle flights

Heathrow to Accra flights

Top 10 airlines flying from Manchester to South America

Airline	Cheapest	Average	Flexibility	On-time
Lufthansa	Cheapest£469	Average£925	FlexibilityNo cancel fee	On-time76%	Search Lufthansa flights
SWISS	Cheapest£588	Average£751	FlexibilityNo cancel fee	On-time79%	Search SWISS flights
Air France	Cheapest£594	Average£966	FlexibilityNo cancel fee	On-time77%	Search Air France flights
Iberia	Cheapest£607	Average£884	FlexibilityNo cancel fee	On-time77%	Search Iberia flights
KLM	Cheapest£611	Average£1,017	FlexibilityNo cancel fee	On-time75%	Search KLM flights
British Airways	Cheapest£644	Average£926	FlexibilityNo cancel fee	On-time70%	Search British Airways flights
Air Canada	Cheapest£656	Average£705	FlexibilityNo cancel fee	On-time67%	Search Air Canada flights
TAP AIR PORTUGAL	Cheapest£664	Average£1,003	FlexibilityNo cancel fee	On-timeN/A	Search TAP AIR PORTUGAL flights
Virgin Atlantic	Cheapest£679	Average£741	FlexibilityNo cancel fee	On-time72%	Search Virgin Atlantic flights
Turkish Airlines	Cheapest£722	Average£783	FlexibilityNo cancel fee	On-time77%	Search Turkish Airlines flights

Fly with Cheapflights

How does Cheapflights help users find flights from Manchester to South America?

Deals for Manchester to South America flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South America?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to South America from Manchester.

Can Cheapflights find flights from Manchester to South America with no change fees?

Need flexible booking options for your flight to South America from Manchester? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South America become cheaper?

Of course! You can now track prices for flights from Manchester to South America and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

Cheap flights from Manchester to South America from £333

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/11. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Manchester to South America

Cheapest flights from Manchester to South AmericaExplore the most affordable flight options available from Manchester to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2026.

Explore the most affordable flight options available from Manchester to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2026.

Best flights from Manchester to South AmericaDiscover carefully curated flight deals from Manchester to South America that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 17 September 2026.

Discover carefully curated flight deals from Manchester to South America that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 17 September 2026.

Last-minute flights from Manchester to South AmericaDiscover last-minute flight deals from Manchester to South America. Data last updated 17 September 2026 and is based on user searches.

Discover last-minute flight deals from Manchester to South America. Data last updated 17 September 2026 and is based on user searches.

One-way flights from Manchester to South AmericaSearch for one-way flight options from Manchester to South America. Find affordable one-way fares based on user searches. Data last updated 17 September 2026.

Search for one-way flight options from Manchester to South America. Find affordable one-way fares based on user searches. Data last updated 17 September 2026.

Find flight deals from Manchester to South America

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to South America that are best for you.

Best time to book a flight from Manchester to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Manchester with our price prediction graph.

Cheapflights Insights

What is the cheapest month to book a flight from Manchester to South America?

How far ahead should I book a flight from Manchester to South America?

Booking 82 days in advance of your planned departure date is, on average, the best time to get cheap flights from Manchester to South America. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Reviews of airlines servicing South America

Read reviews from past customers who have flown with KLM,Air France, andTAP AIR PORTUGAL from Manchester to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Manchester to South America?

How long is the flight from Manchester to South America?

What are the cheapest airlines to fly from Manchester to South America one-way?

What are the most popular routes from Manchester to South America?

Can I find deals for flights from Manchester to South America that include hotel bookings?

How can I find direct flights from Manchester to South America?

Can I find deals for business class flights from Manchester to South America?

What is the cheapest month to book a flight from Manchester to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to South America

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to South America by adding a car hire and/or hotel booking to your travel itinerary.

Direct flights to

Book a non-stop flight to one of these other cities located in .

Search flights from Manchester to South America by cabin class

Find flights from Manchester to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Manchester and South America flights

Browse other Manchester and South America flight options. Last updated on 17 September 2026.

Popular flight searches

Check out other popular destinations found by fellow travellers in 2026

Fly to South America countries

Consider these flights travelling to countries located in South America.

Manchester to South America flights

Consider these flights travelling from Manchester to South America.

Top 10 airlines flying from Manchester to South America

Fly with Cheapflights

How does Cheapflights help users find flights from Manchester to South America?

Why should you use Cheapflights to find cheap flight tickets from Manchester to South America?

Can Cheapflights find flights from Manchester to South America with no change fees?

Can Cheapflights notify me if prices for flights from Manchester to South America become cheaper?

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Manchester to South America
Explore the most affordable flight options available from Manchester to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2026.

Best flights from Manchester to South America
Discover carefully curated flight deals from Manchester to South America that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 17 September 2026.

Last-minute flights from Manchester to South America
Discover last-minute flight deals from Manchester to South America. Data last updated 17 September 2026 and is based on user searches.

One-way flights from Manchester to South America
Search for one-way flight options from Manchester to South America. Find affordable one-way fares based on user searches. Data last updated 17 September 2026.