Cheap flights from London Heathrow Airport to South Carolina from £321

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/4. Fares are subject to change and may not be available on all flights or dates of travel.
LHR — CHS
2 May — 9 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Heathrow to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Heathrow to South Carolina
Explore the most affordable flight options available from Heathrow to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 2 April 2026.

Mon 4/508:15
LHR
-
SAV
1 stop30h 37m
JetBlue
Mon 11/510:41
SAV
-
LHR
1 stop17h 49m
JetBlue
Deal found 31/3£518
Wed 22/406:00
LHR
-
MYR
2 stops18h 04m
Multiple Airlines
Fri 1/510:20
MYR
-
LHR
1 stop15h 55m
Multiple Airlines
Deal found 31/3£521
Mon 4/508:15
LHR
-
CHS
1 stop13h 42m
JetBlue
Tue 19/511:24
CHS
-
LHR
1 stop17h 06m
JetBlue
Deal found 28/3£523
Sun 26/411:55
LHR
-
CHS
1 stop27h 33m
JetBlue
Tue 5/509:44
CHS
-
LHR
1 stop15h 46m
JetBlue
Deal found 30/3£524
Fri 15/511:55
LHR
-
CHS
1 stop27h 28m
JetBlue
Fri 22/515:45
CHS
-
LHR
1 stop12h 45m
JetBlue
Deal found 31/3£527
Mon 20/408:15
LHR
-
CHS
1 stop13h 17m
JetBlue
Wed 6/509:44
CHS
-
LHR
1 stop15h 46m
JetBlue
Deal found 28/3£532
Tue 12/508:40
LHR
-
CHS
1 stop11h 58m
JetBlue
Tue 19/511:24
CHS
-
LHR
1 stop17h 06m
JetBlue
Deal found 28/3£536
Sat 9/508:15
LHR
-
CHS
1 stop13h 42m
JetBlue
Fri 15/517:59
CHS
-
LHR
1 stop10h 31m
JetBlue
Deal found 29/3£537
Mon 7/908:15
LHR
-
SAV
1 stop29h 38m
JetBlue
Mon 28/914:20
SAV
-
LHR
1 stop14h 10m
JetBlue
Deal found 31/3£552
Sat 25/411:55
LHR
-
CHS
1 stop34h 05m
JetBlue
Mon 11/517:59
CHS
-
LHR
1 stop10h 31m
JetBlue
Deal found 31/3£557
Fri 1/516:00
LHR
-
SAV
1 stop12h 58m
United Airlines
Mon 4/506:00
SAV
-
LHR
1 stop10h 35m
United Airlines
Deal found 1/4£558
Sat 25/408:15
LHR
-
CHS
1 stop13h 42m
JetBlue
Wed 6/509:44
CHS
-
LHR
1 stop15h 46m
JetBlue
Deal found 30/3£558

Find flight deals from Heathrow to South Carolina

Keep the following information in mind while searching for Heathrow to South Carolina flight deals. Data was last updated 2 April 2026.

Round-trip from

£518

One-way from

£321

Popular in

December

Cheapest in

September

Average price

£668
JetBlue
  • JetBlue
  • 4/5-11/5
  • 2 total stops
  • 48h 26m total
  • London to South Carolina
23/4
  • 23/4
  • 2 total stops
  • 38h 58m total
  • London to South Carolina
High demand for flights, 0% potential price rise
Cheapest flight prices on average. 2% potential price decrease (£12 potential savings vs. average return price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customise your flight search to find flights from Heathrow to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 April 2026.
Use the filters below to find and compare flights from London Heathrow Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

LondonMyrtle Beach

LHR - MYR

LHRMYR

London Heathrow

Wed 22/4

06:00-19:04

2 stops18h 04m

Myrtle Beach Intl

Fri 1/5

10:20-21:40

2 stops30h 20m

£554

LondonCharleston

LHR - CHS

LHRCHS

London Heathrow

Sun 26/4

08:15-16:57

1 stop13h 42m

Charleston

Wed 6/5

09:44-06:30

1 stop15h 46m

£602

LondonColumbia

LHR - CAE

LHRCAE

London Heathrow

Wed 29/4

08:40-21:21

2 stops17h 41m

Columbia Metropolitan

Wed 6/5

10:35-06:55

2 stops15h 20m

£679

LondonGreenville

LHR - GSP

LHRGSP

London Heathrow

Wed 29/4

08:40-20:47

2 stops17h 07m

Greenville

Wed 6/5

07:00-08:20

2 stops20h 20m

£679

LondonGreenville

LHR - GSP

LHRGSP

London Heathrow

Tue 28/4

08:45-20:47

2 stops17h 02m

Greenville

Tue 5/5

18:27-10:25

1 stop10h 58m

£680

LondonColumbia

LHR - CAE

LHRCAE

London Heathrow

Mon 4/5

07:30-19:03

2 stops16h 33m

Columbia Metropolitan

Mon 11/5

19:38-20:40

2 stops20h 02m

£684

LondonGreenville

LHR - GSP

LHRGSP

London Heathrow

Tue 12/5

08:45-22:58

2 stops19h 13m

Greenville

Tue 19/5

12:07-05:55

1 stop12h 48m

£684

LondonSavannah

LHR - SAV

LHRSAV

London Heathrow

Wed 13/5

06:55-19:26

2 stops17h 31m

Savannah/Hilton Head

Wed 20/5

06:00-21:25

1 stop10h 25m

£685

LondonColumbia

LHR - CAE

LHRCAE

London Heathrow

Mon 27/4

16:40-23:59

1 stop12h 19m

Columbia Metropolitan

Mon 4/5

10:35-11:55

1 stop20h 20m

£691

LondonGreenville

LHR - GSP

LHRGSP

London Heathrow

Thu 30/4

09:00-22:58

2 stops18h 58m

Greenville

Thu 7/5

14:52-06:55

1 stop11h 03m

£692

Flights are sorted by cheapest return flights first.

Deals found on 28/3

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Heathrow to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Heathrow with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from London Heathrow Airport to South Carolina

What is the cheapest month to book a flight from London Heathrow Airport to South Carolina?

Currently, July is the cheapest month in which you can book a flight from London Heathrow Airport to South Carolina (average of £287). Flying from London Heathrow Airport to South Carolina in June is currently the most expensive (average of £557). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from London Heathrow Airport to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 2 April 2026.
Read reviews from past customers who have flown with Virgin Atlantic,United Airlines, andJetBlue from London Heathrow Airport to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

6.9

Overall

7.5

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Food

6.9

Overall

7.5

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Food

6.9

Overall

7.5

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Food

6.9

Overall

7.5

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Food

6.9

Overall

7.5

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Food

6.9

Overall

7.5

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.5

Reviews

1 / 20
6.0
Good

Pratap,Aug 2025

JFK - LHR

The flight is clean, food good and the staff are excellent! Very professional, polite and accommodating. The seat itself is really mediocre. Can’t believe there is not inch of storage space. Believe it or not it there is not place even to put away your phone or pen!! Very very surprising and terribly inconvenient. No coat hanger hook either. Had to give it away. ALL IN ALL VERY INCONVENIENT business class seat compared to their peers. What is even more surprising is that this on their relatively new fleet of Airbus A350-1000. I was having com platelets different expectations of Virgin and this has disappointed me. Everything else is just as good and as you would expect from Virgin!

Related info for your journey

Find useful and relevant information for your journey from Heathrow to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from London Heathrow Airport to South Carolina?

    There are many flights that can get you from London Heathrow Airport to South Carolina in 12h 19m. Fly via JetBlue, United Airlines, or Lufthansa to get the fastest option. The distance between London Heathrow Airport and South Carolina is about 4048 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most popular routes from London Heathrow Airport to South Carolina?

  • Can I find deals for flights from Heathrow to South Carolina that include hotel bookings?

    Yes. In addition to deals on Heathrow to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Heathrow to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Heathrow to South Carolina.

  • Can I find deals for business class flights from Heathrow to South Carolina?

    Yes. Cheapflights offers flight deals from Heathrow to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from London Heathrow Airport to South Carolina?

    Currently, July is the cheapest month in which you can book a flight from London Heathrow Airport to South Carolina (average of £287). Flying from London Heathrow Airport to South Carolina in June is currently the most expensive (average of £557). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Heathrow to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from Heathrow to South Carolina

Discover the top 10 airlines that operate flights from Heathrow to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 2 April 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest£194Average£568FlexibilityNo cancel feeOn-time62%
Search JetBlue flights
United AirlinesCheapest£240Average£689FlexibilityNo cancel feeOn-time69%
Search United Airlines flights
LufthansaCheapest£463Average£752FlexibilityNo cancel feeOn-time76%
Search Lufthansa flights
Virgin AtlanticCheapest£471Average£647FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
IcelandairCheapest£490Average£632FlexibilityNo cancel feeOn-time76%
Search Icelandair flights
British AirwaysCheapest£494Average£632FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Air FranceCheapest£499Average£865FlexibilityNo cancel feeOn-time77%
Search Air France flights
KLMCheapest£499Average£648FlexibilityNo cancel feeOn-time75%
Search KLM flights
Air CanadaCheapest£499Average£713FlexibilityNo cancel feeOn-time67%
Search Air Canada flights
FinnairCheapest£501Average£584FlexibilityNo cancel feeOn-time76%
Search Finnair flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Heathrow to South Carolina?

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Why should you use Cheapflights to find cheap flight tickets from Heathrow to South Carolina?

Cheapflights helps you find that perfect flight to South Carolina from Heathrow by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Heathrow to South Carolina with no change fees?

Need flexible booking options for your flight to South Carolina from Heathrow? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Heathrow to South Carolina become cheaper?

Yes! Start tracking prices for Heathrow to South Carolina flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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