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Cheap flights from Manchester to South Carolina from £277

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/1. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
29 Nov — 6 Dec1
1 adult
1 adult, Economy, 0 bags

Find flight deals from Manchester to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 October 2025.

Sun 23/1107:50MAN - CLT
3 stops29h 59mMultiple Airlines
Sun 30/1109:30CLT - MAN
2 stops33h 25mMultiple Airlines
Deal found 28/10£640
Sat 6/1216:55MAN - CLT
3 stops31h 15mMultiple Airlines
Sun 14/1212:59CLT - MAN
3 stops27h 46mMultiple Airlines
Deal found 29/10£662
Fri 21/1119:25MAN - CLT
2 stops42h 24mMultiple Airlines
Fri 28/1118:50CLT - MAN
1 stop17h 05mMultiple Airlines
Deal found 29/10£678
Mon 24/1106:05MAN - CHS
2 stops15h 39mAmerican Airlines
Mon 1/1219:53CHS - MAN
2 stops14h 17mAmerican Airlines
Deal found 28/10£693
Mon 24/1111:50MAN - CHS
2 stops16h 20mBritish Airways
Sun 30/1118:32CHS - MAN
2 stops16h 03mBritish Airways
Deal found 27/10£699
Thu 11/1213:30MAN - SAV
1 stop12h 25mVirgin Atlantic
Thu 18/1212:30SAV - MAN
2 stops14h 25mVirgin Atlantic
Deal found 27/10£709
Mon 24/1113:00MAN - CHS
1 stop12h 32mKLM
Mon 1/1212:53CHS - MAN
2 stops14h 27mKLM
Deal found 28/10£720
Mon 24/1109:40MAN - CHS
2 stops18h 30mAmerican Airlines
Sun 30/1119:27CHS - MAN
2 stops15h 08mAmerican Airlines
Deal found 28/10£724
Mon 24/1106:30MAN - CHS
3 stops29h 56mMultiple Airlines
Sun 30/1108:31CHS - MAN
3 stops34h 24mMultiple Airlines
Deal found 27/10£727
Sat 22/1110:30MAN - CLT
1 stop14h 27mMultiple Airlines
Sat 29/1109:01CLT - MAN
1 stop16h 59mMultiple Airlines
Deal found 29/10£748
Fri 7/1106:45MAN - CLT
3 stops30h 02mMultiple Airlines
Fri 14/1106:00CLT - MAN
2 stops20h 35mMultiple Airlines
Deal found 29/10£774
Sat 22/1113:00MAN - CLT
2 stops30h 40mMultiple Airlines
Fri 28/1106:00CLT - MAN
1 stop19h 40mMultiple Airlines
Deal found 29/10£786

Cheap flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 30 October 2025.

Round-trip from

£575

One-way from

£277

Popular in

December

Cheapest in

September

Average price

£769
11/12-18/12
  • 11/12-18/12
  • 3 total stops
  • 40h 56m total
  • Manchester to South Carolina
Search Deals
19/1
  • 19/1
  • 3 total stops
  • 51h 26m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (£36 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£18 potential savings vs. average return price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 October 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sun 23/11

07:50-08:49

3 stops29h 59m

Charlotte Douglas

Sun 30/11

09:30-23:55

2 stops33h 25m

£640

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Wed 22/4

19:10-23:57

2 stops33h 47m

Charlotte Douglas

Tue 12/5

06:00-08:55

2 stops21h 55m

£653

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sat 6/12

16:55-19:10

3 stops31h 15m

Charlotte Douglas

Sun 14/12

12:59-21:45

3 stops27h 46m

£662

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Mon 24/11

06:05-16:44

2 stops15h 39m

Charleston

Mon 1/12

19:53-15:10

2 stops14h 17m

£693

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Mon 24/11

11:50-23:10

2 stops16h 20m

Charleston

Sun 30/11

18:32-15:35

2 stops16h 03m

£699

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Thu 11/12

13:30-20:55

1 stop12h 25m

Savannah/Hilton Head

Thu 18/12

12:30-07:55

2 stops14h 25m

£709

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 4/3

09:50-22:53

2 stops18h 03m

Charleston

Sun 8/3

18:34-14:00

2 stops15h 26m

£715

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Fri 6/3

11:50-22:28

2 stops15h 38m

Myrtle Beach Intl

Tue 10/3

20:41-17:35

2 stops16h 54m

£715

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Thu 5/3

05:40-17:33

2 stops16h 53m

Savannah/Hilton Head

Mon 9/3

20:21-18:40

2 stops18h 19m

£715

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Mon 24/11

13:00-20:32

1 stop12h 32m

Charleston

Mon 1/12

12:53-08:20

2 stops14h 27m

£720

Flights are sorted by cheapest return flights first.

Deals found on 29/10

Showing 1-10 of 39 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £529). Flying from Manchester to South Carolina in June is currently the most expensive (average of £640). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 October 2025.

It’s typically best to fly out from Manchester to South Carolina at midday. Doing so could potentially save you 16% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 30 October 2025.
See what other customers who have flown with KLM, Finnair, andVirgin Atlantic from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.7
Good
1,406 reviews
Check prices

Comfort

7.7

Overall

7.7

Food

7.3

Crew

8.4

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
KLM
7.7
Good
1,406 reviews
KLM
7.7
Good
1,406 reviews
Check prices

Comfort

7.7

Overall

7.7

Food

7.3

Crew

8.4

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Finnair
7.6
Good
1,333 reviews
KLM
7.7
Good
1,406 reviews
Check prices

Comfort

7.7

Overall

7.7

Food

7.3

Crew

8.4

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Virgin Atlantic
7.5
Good
670 reviews
KLM
7.7
Good
1,406 reviews
Check prices

Comfort

7.7

Overall

7.7

Food

7.3

Crew

8.4

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
Aer Lingus
7.2
Good
1,361 reviews
KLM
7.7
Good
1,406 reviews
Check prices

Comfort

7.7

Overall

7.7

Food

7.3

Crew

8.4

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.
British Airways
6.7
Okay
7,487 reviews
KLM
7.7
Good
1,406 reviews
Check prices

Comfort

7.7

Overall

7.7

Food

7.3

Crew

8.4

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
2.0
Mediocre

Abisola,Oct 2025

LOS - CDG

The food option was finished and what wa left was vegan pasta so I had to go without food for an 8 hour flight without any sort of empathy from crew that was mean.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Manchester to South Carolina?

    Scandinavian Airlines, American Airlines, and British Airways can get you from Manchester to South Carolina in just under 15h 39m. Your travel time can differ by up to 18h 08m. Manchester and South Carolina are separated by a distance of 3948 mi. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Charleston or Manchester - Myrtle Beach Intl, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £529). Flying from Manchester to South Carolina in June is currently the most expensive (average of £640). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Manchester to South Carolina

Discover the top 7 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 October 2025.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£520Average£658FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£546Average£704FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Air FranceCheapest£560Average£835FlexibilityNo cancel feeOn-time77%
Search Air France flights
Virgin AtlanticCheapest£574Average£732FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£588Average£823FlexibilityNo cancel feeOn-time75%
Search KLM flights
DeltaCheapest£632Average£779FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Aer LingusCheapest£795Average£966FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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