How long is the flight from Manchester to South Carolina?

British Airways, United Airlines, and Virgin Atlantic can get you from Manchester to South Carolina in just under 12h 52m. Your travel time can differ by up to 24h 10m. Manchester and South Carolina are separated by a distance of 3948 mi. Both multi-stop and direct flights can be found to your destination and back.

In terms of precipitation, rainfall in South Carolina ranges from 61.0 - 183.0 inches per month. August is typically the wettest month, when rainfall can reach 183.0 mm. November is typically the driest time to visit South Carolina when rainfall is around 61.0 mm.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 28.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 9.0 C).

What are the most popular routes from Manchester to South Carolina?

While some choose either Manchester - Charleston or Manchester - Myrtle Beach Intl, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

What are the most popular airlines that fly from Manchester to South Carolina?

Consider Air France, Finnair or British Airways when booking your flight. These represent the most popular airlines when flying from Manchester to South Carolina.

What airport do you fly from for flights from Manchester to South Carolina?

For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Manchester to South Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

Can I find deals for business class flights from Manchester to South Carolina?

Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£256+ Flights from Manchester to South Carolina

Cheap flight deals from Manchester to South Carolina

Round-trip from	£524
One-way from	£256
Popular in	December
Cheapest in	February
Average price	£639

Lufthansa
18/2-25/2
4 total stops
34h 52m total
Manchester to South Carolina

Search Deals

21/10
2 total stops
52h 58m total
Manchester to South Carolina

Search Deals

Highest demand for flights based on searches. 2% potential increase in price (£14 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease (£16 potential savings vs. average return price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Find flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2025.

Thu 30/1018:00MAN - MYR

3 stops33h 57mMultiple Airlines

Thu 6/1114:59MYR - MAN

3 stops38h 36mMultiple Airlines

Deal found 15/9£539

Mon 22/912:35MAN - MYR

1 stop16h 14mVirgin Atlantic

Mon 29/918:55MYR - MAN

1 stop32h 40mVirgin Atlantic

Deal found 15/9£546

Tue 7/1010:40MAN - GSP

2 stops32h 31mUnited Airlines

Sat 8/1110:00GSP - MAN

2 stops26h 00mUnited Airlines

Deal found 16/9£548

Thu 30/1006:00MAN - CAE

2 stops19h 30mUnited Airlines

Thu 6/1110:20CAE - MAN

2 stops17h 25mUnited Airlines

Deal found 15/9£548

Wed 29/1006:00MAN - GSP

2 stops36h 20mUnited Airlines

Wed 5/1109:10GSP - MAN

2 stops18h 30mUnited Airlines

Deal found 14/9£548

Mon 22/908:55MAN - MYR

2 stops35h 36mAmerican Airlines

Mon 29/917:36MYR - MAN

2 stops16h 34mAmerican Airlines

Deal found 15/9£566

Mon 22/912:35MAN - MYR

1 stop16h 14mDelta

Mon 29/914:20MYR - MAN

2 stops18h 05mDelta

Deal found 15/9£570

Wed 29/1013:30MAN - GSP

1 stop14h 25mDelta

Wed 5/1109:54GSP - MAN

2 stops19h 16mDelta

Deal found 14/9£570

Fri 31/1006:05MAN - GSP

2 stops18h 44mUnited Airlines

Fri 7/1112:25GSP - MAN

2 stops18h 55mUnited Airlines

Deal found 16/9£584

Thu 30/1013:30MAN - MYR

1 stop24h 21mDelta

Thu 6/1111:29MYR - MAN

2 stops17h 41mDelta

Deal found 15/9£590

Thu 30/1013:30MAN - CAE

1 stop27h 00mDelta

Thu 6/1114:58CAE - MAN

2 stops20h 37mDelta

Deal found 15/9£594

Tue 7/1012:35MAN - GSP

1 stop16h 20mDelta

Sat 8/1111:29GSP - MAN

2 stops17h 41mDelta

Deal found 16/9£601

Best flights from Manchester to South Carolina
Discover carefully curated flight deals from Manchester to South Carolina that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 17 September 2025.

Mon 2/306:05MAN - CHS

2 stops16h 24mBritish Airways

Tue 10/316:03CHS - MAN

2 stops15h 22mBritish Airways

Deal found 16/9£530

Thu 5/306:10MAN - CAE

2 stops37h 02mUnited Airlines

Wed 25/310:00CAE - MAN

2 stops20h 20mUnited Airlines

Deal found 16/9£538

Mon 2/313:00MAN - CHS

1 stop12h 52mVirgin Atlantic

Tue 10/319:59CHS - MAN

2 stops30h 41mVirgin Atlantic

Deal found 16/9£539

Thu 30/1018:00MAN - MYR

3 stops33h 57mMultiple Airlines

Thu 6/1114:59MYR - MAN

3 stops38h 36mMultiple Airlines

Deal found 15/9£539

Wed 4/308:55MAN - CHS

2 stops15h 08mAmerican Airlines

Sun 8/320:16CHS - MAN

2 stops17h 49mAmerican Airlines

Deal found 14/9£560

Wed 29/1013:30MAN - GSP

1 stop14h 25mDelta

Wed 5/1109:54GSP - MAN

2 stops19h 16mDelta

Deal found 14/9£570

Fri 6/313:25MAN - MYR

1 stop15h 10mKLM

Tue 10/314:15MYR - MAN

2 stops14h 05mKLM

Deal found 15/9£633

Fri 6/319:15MAN - CLT

2 stops33h 39mScandinavian Airlines

Tue 10/311:30CLT - MAN

2 stops27h 05mScandinavian Airlines

Deal found 14/9£708

Thu 5/309:25MAN - SAV

2 stops19h 27mUnited Airlines

Mon 9/314:10SAV - MAN

2 stops18h 10mUnited Airlines

Deal found 15/9£542

Thu 5/306:10MAN - CAE

3 stops19h 55mMultiple Airlines

Wed 25/314:40CAE - MAN

2 stops15h 40mMultiple Airlines

Deal found 16/9£544

Fri 6/306:00MAN - MYR

2 stops16h 29mAmerican Airlines

Tue 10/314:29MYR - MAN

2 stops19h 31mAmerican Airlines

Deal found 14/9£560

Thu 5/313:30MAN - SAV

1 stop15h 29mDelta

Mon 9/318:50SAV - MAN

2 stops19h 50mDelta

Deal found 14/9£587

Wed 4/313:30MAN - CHS

1 stop15h 09mVirgin Atlantic

Sun 8/312:45CHS - MAN

2 stops15h 35mVirgin Atlantic

Deal found 14/9£592

Tue 7/1010:40MAN - GSP

2 stops32h 31mUnited Airlines

Sat 8/1110:00GSP - MAN

2 stops26h 00mUnited Airlines

Deal found 16/9£548

Thu 30/1013:30MAN - MYR

1 stop24h 21mDelta

Thu 6/1111:29MYR - MAN

2 stops17h 41mDelta

Deal found 15/9£590

Thu 30/1006:00MAN - CAE

2 stops19h 30mUnited Airlines

Thu 6/1110:20CAE - MAN

2 stops17h 25mUnited Airlines

Deal found 15/9£548

Wed 4/313:00MAN - CHS

1 stop12h 52mKLM

Sun 8/315:50CHS - MAN

2 stops16h 55mKLM

Deal found 16/9£679

Wed 29/1006:10MAN - GSP

3 stops17h 00mMultiple Airlines

Wed 5/1112:30GSP - MAN

2 stops15h 10mMultiple Airlines

Deal found 14/9£636

Sun 12/1020:40MAN - GSP

2 stops25h 01mVirgin Atlantic

Sat 15/1111:42GSP - MAN

2 stops17h 28mVirgin Atlantic

Deal found 14/9£645

Mon 24/1119:15MAN - CLT

2 stops31h 42mScandinavian Airlines

Mon 1/1217:11CLT - MAN

2 stops20h 24mScandinavian Airlines

Deal found 15/9£713

Fri 6/313:25MAN - MYR

1 stop25h 43mDelta

Tue 10/311:10MYR - MAN

2 stops15h 30mDelta

Deal found 14/9£591

Wed 29/1006:00MAN - GSP

2 stops36h 20mUnited Airlines

Wed 5/1109:10GSP - MAN

2 stops18h 30mUnited Airlines

Deal found 14/9£548

Thu 5/313:30MAN - CAE

1 stop15h 24mDelta

Wed 25/311:55CAE - MAN

1 stop18h 35mDelta

Deal found 16/9£592

Thu 30/1006:25MAN - CLT

1 stop15h 30mMultiple Airlines

Thu 6/1118:50CLT - MAN

1 stop21h 55mMultiple Airlines

Deal found 15/9£677

Fri 6/306:00MAN - CLT

1 stop15h 05mAmerican Airlines

Tue 10/323:50CLT - MAN

1 stop14h 55mAmerican Airlines

Deal found 14/9£760

Fri 31/1006:05MAN - GSP

2 stops18h 44mUnited Airlines

Fri 7/1112:25GSP - MAN

2 stops18h 55mUnited Airlines

Deal found 16/9£584

Thu 30/1013:30MAN - CAE

1 stop27h 00mDelta

Thu 6/1114:58CAE - MAN

2 stops20h 37mDelta

Deal found 15/9£594

Tue 7/1012:35MAN - GSP

1 stop14h 43mVirgin Atlantic

Sat 8/1110:54GSP - MAN

1 stop18h 36mVirgin Atlantic

Deal found 16/9£744

Thu 25/1219:15MAN - CLT

2 stops31h 55mScandinavian Airlines

Sun 4/107:10CLT - MAN

2 stops21h 20mScandinavian Airlines

Deal found 13/9£830

Mon 15/1214:15MAN - CLT

1 stop14h 07mMultiple Airlines

Mon 29/1218:50CLT - MAN

2 stops18h 35mMultiple Airlines

Deal found 15/9£696

Last-minute flights from Manchester to South Carolina
Discover last-minute flight deals from Manchester to South Carolina. Data last updated 17 September 2025 and is based on user searches.

Mon 22/912:35MAN - MYR

1 stop16h 14mVirgin Atlantic

Mon 29/918:55MYR - MAN

1 stop32h 40mVirgin Atlantic

Deal found 15/9£546

Mon 22/908:55MAN - MYR

2 stops35h 36mAmerican Airlines

Mon 29/917:36MYR - MAN

2 stops16h 34mAmerican Airlines

Deal found 15/9£566

Mon 22/912:35MAN - MYR

1 stop16h 14mDelta

Mon 29/914:20MYR - MAN

2 stops18h 05mDelta

Deal found 15/9£570

Tue 7/1010:40MAN - GSP

2 stops32h 31mUnited Airlines

Sat 8/1110:00GSP - MAN

2 stops26h 00mUnited Airlines

Deal found 16/9£548

Tue 7/1012:35MAN - GSP

1 stop16h 20mDelta

Sat 8/1111:29GSP - MAN

2 stops17h 41mDelta

Deal found 16/9£601

Wed 29/1006:00MAN - GSP

2 stops36h 20mUnited Airlines

Wed 5/1109:10GSP - MAN

2 stops18h 30mUnited Airlines

Deal found 14/9£548

Wed 29/1013:30MAN - GSP

1 stop14h 25mDelta

Wed 5/1109:54GSP - MAN

2 stops19h 16mDelta

Deal found 14/9£570

Thu 30/1018:00MAN - MYR

3 stops33h 57mMultiple Airlines

Thu 6/1114:59MYR - MAN

3 stops38h 36mMultiple Airlines

Deal found 15/9£539

Thu 30/1006:00MAN - CAE

2 stops19h 30mUnited Airlines

Thu 6/1110:20CAE - MAN

2 stops17h 25mUnited Airlines

Deal found 15/9£548

Thu 30/1013:30MAN - MYR

1 stop24h 21mDelta

Thu 6/1111:29MYR - MAN

2 stops17h 41mDelta

Deal found 15/9£590

Thu 30/1013:30MAN - CAE

1 stop27h 00mDelta

Thu 6/1114:58CAE - MAN

2 stops20h 37mDelta

Deal found 15/9£594

Fri 31/1006:05MAN - GSP

2 stops18h 44mUnited Airlines

Fri 7/1112:25GSP - MAN

2 stops18h 55mUnited Airlines

Deal found 16/9£584

One-way flights from Manchester to South Carolina
Search for one-way flight options from Manchester to South Carolina. Find affordable one-way fares based on user searches. Data last updated 17 September 2025.

Tue 21/1016:05MAN - CLT

2 stops52h 58mMultiple Airlines

Deal found 15/9£256

Tue 30/906:30MAN - SAV

2 stops57h 35mMultiple Airlines

Deal found 15/9£273

Thu 9/1006:25MAN - CLT

2 stops33h 44mMultiple Airlines

Deal found 15/9£321

Thu 16/1015:45MAN - CLT

3 stops46h 39mMultiple Airlines

Deal found 15/9£323

Wed 15/1020:10MAN - CLT

3 stops41h 50mMultiple Airlines

Deal found 15/9£324

Mon 20/1021:40MAN - CLT

3 stops44h 55mMultiple Airlines

Deal found 15/9£333

Sat 18/1021:15MAN - CLT

3 stops44h 41mMultiple Airlines

Deal found 15/9£353

Thu 2/1014:20MAN - CLT

3 stops51h 41mMultiple Airlines

Deal found 15/9£354

Sun 28/911:45MAN - SAV

3 stops52h 20mMultiple Airlines

Deal found 15/9£360

Mon 29/918:00MAN - SAV

3 stops46h 05mMultiple Airlines

Deal found 15/9£363

Fri 17/1007:40MAN - CLT

3 stops33h 59mMultiple Airlines

Deal found 15/9£393

Sat 1/1111:25MAN - CAE

3 stops31h 44mMultiple Airlines

Deal found 15/9£446

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Mon 2/3

06:05-17:29

2 stops16h 24m

Charleston

Tue 10/3

16:03-11:25

2 stops15h 22m

£530

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Thu 5/3

06:10-14:12

2 stops37h 02m

Columbia Metropolitan

Wed 25/3

10:00-10:20

2 stops20h 20m

£538

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Mon 2/3

13:00-20:52

1 stop12h 52m

Charleston

Tue 10/3

19:59-06:40

2 stops30h 41m

£539

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Thu 30/10

18:00-23:57

3 stops33h 57m

Myrtle Beach Intl

Thu 6/11

14:59-10:35

3 stops38h 36m

£539

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Thu 5/3

09:25-23:52

2 stops19h 27m

Savannah/Hilton Head

Mon 9/3

14:10-12:20

2 stops18h 10m

£542

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Thu 5/3

06:10-21:05

3 stops19h 55m

Columbia Metropolitan

Wed 25/3

14:40-10:20

2 stops15h 40m

£544

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 7/10

10:40-14:11

2 stops32h 31m

Greenville

Sat 8/11

10:00-17:00

2 stops26h 00m

£548

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Thu 30/10

06:00-21:30

2 stops19h 30m

Columbia Metropolitan

Thu 6/11

10:20-08:45

2 stops17h 25m

£548

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Wed 29/10

06:00-14:20

2 stops36h 20m

Greenville

Wed 5/11

09:10-08:40

2 stops18h 30m

£548

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 4/3

08:55-19:03

2 stops15h 08m

Charleston

Sun 8/3

20:16-18:05

2 stops17h 49m

£560

Flights are sorted by cheapest return flights first.

Deals found on 15/9

Showing 1-10 of 43 results

...

Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to SC?

When flying from Manchester to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

See what other customers who have flown with KLM, Finnair, andAir France from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

KLM

7.8

Good

1,386 reviews

Check prices

Reviews

1 / 20

4.0

Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

KLM

7.8

Good

1,386 reviews

KLM

7.8

Good

1,386 reviews

Check prices

Reviews

1 / 20

4.0

Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Finnair

7.6

Good

1,324 reviews

KLM

7.8

Good

1,386 reviews

Check prices

Reviews

1 / 20

4.0

Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Air France

7.4

Good

1,468 reviews

KLM

7.8

Good

1,386 reviews

Check prices

Reviews

1 / 20

4.0

Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Virgin Atlantic

7.4

Good

664 reviews

KLM

7.8

Good

1,386 reviews

Check prices

Reviews

1 / 20

4.0

Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

British Airways

6.7

Okay

7,363 reviews

KLM

7.8

Good

1,386 reviews

Check prices

Reviews

1 / 20

4.0

Okay

Mark,Sept 2025

AMS - BHX

Crew and snacks were good, boarding wasn't great as busses were used rather than boarding tunnels. Also endured a one hour delay.

Related info for your journey

What airport do you fly from for flights from Manchester to South Carolina?
For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.
How long is the flight from Manchester to South Carolina?
British Airways, United Airlines, and Virgin Atlantic can get you from Manchester to South Carolina in just under 12h 52m. Your travel time can differ by up to 24h 10m. Manchester and South Carolina are separated by a distance of 3948 mi. Both multi-stop and direct flights can be found to your destination and back.
What are the most popular routes from Manchester to South Carolina?
While some choose either Manchester - Charleston or Manchester - Myrtle Beach Intl, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.
Can I find deals for flights from Manchester to South Carolina that include hotel bookings?
Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Manchester to South Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.
Can I find deals for business class flights from Manchester to South Carolina?
Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Manchester to South Carolina?
Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Manchester to South Carolina

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Complete your trip

South Carolina car hire

Charleston Airport car hire

Myrtle Beach Intl Airport car hire

Greenville Airport car hire

Columbia Metropolitan Airport car hire

Hilton Head Island Airport car hire

Florence Airport car hire

Myrtle Beach car hire

Charleston car hire

Greenville car hire

Columbia car hire

Direct flights to United States

Top 8 airlines flying from Manchester to South Carolina

Airline	Cheapest	Average	Flexibility	On-time
Finnair	Cheapest£517	Average£635	FlexibilityNo cancel fee	On-time76%	Search Finnair flights
British Airways	Cheapest£529	Average£688	FlexibilityNo cancel fee	On-time70%	Search British Airways flights
Air France	Cheapest£543	Average£742	FlexibilityNo cancel fee	On-time77%	Search Air France flights
Virgin Atlantic	Cheapest£564	Average£710	FlexibilityNo cancel fee	On-time72%	Search Virgin Atlantic flights
KLM	Cheapest£570	Average£783	FlexibilityNo cancel fee	On-time75%	Search KLM flights
American Airlines	Cheapest£584	Average£719	FlexibilityNo cancel fee	On-time71%	Search American Airlines flights
Delta	Cheapest£613	Average£720	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
Aer Lingus	Cheapest£771	Average£936	FlexibilityNo cancel fee	On-timeN/A	Search Aer Lingus flights

Fly with Cheapflights

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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Cheap flights from Manchester to South Carolina from £256

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/10. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 17 September 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South CarolinaExplore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2025.

Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

What is the cheapest time of day to fly from MAN to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 17 September 2025.

Reviews of airlines servicing South Carolina

See what other customers who have flown with KLM, Finnair, andAir France from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

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Top 8 airlines flying from Manchester to South Carolina

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Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2025.