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Cheap flights from Manchester to South Carolina from £282

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
3 Jan — 10 Jan1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 4 December 2025.

Tue 23/1208:30MAN - CLT
3 stops40h 39mMultiple Airlines
Wed 7/110:34CLT - MAN
3 stops19h 11mMultiple Airlines
Deal found 1/12£681
Thu 4/1218:05MAN - CLT
3 stops34h 54mMultiple Airlines
Tue 9/1212:59CLT - MAN
2 stops24h 36mMultiple Airlines
Deal found 1/12£740
Wed 24/1207:10MAN - CLT
2 stops30h 22mMultiple Airlines
Thu 1/118:50CLT - MAN
1 stop34h 40mMultiple Airlines
Deal found 2/12£862
Tue 30/1213:30MAN - GSP
1 stop24h 49mMultiple Airlines
Tue 6/117:12GSP - MAN
2 stops32h 28mMultiple Airlines
Deal found 2/12£898
Tue 30/1205:50MAN - GSP
2 stops18h 23mVirgin Atlantic
Tue 6/117:12GSP - MAN
2 stops32h 28mVirgin Atlantic
Deal found 2/12£900
Wed 31/1206:00MAN - CLT
2 stops57h 31mUnited Airlines
Mon 5/119:44CLT - MAN
2 stops35h 36mUnited Airlines
Deal found 1/12£904
Mon 29/1206:10MAN - CLT
2 stops20h 10mUnited Airlines
Mon 5/119:44CLT - MAN
2 stops33h 36mUnited Airlines
Deal found 1/12£929
Thu 25/1211:40MAN - CLT
1 stop12h 20mBritish Airways
Sun 28/1223:00CLT - MAN
1 stop14h 05mBritish Airways
Deal found 2/12£932
Tue 30/1213:30MAN - GSP
1 stop27h 28mDelta
Tue 6/108:22GSP - MAN
1 stop21h 08mDelta
Deal found 2/12£998
Sat 13/1217:35MAN - GSP
2 stops32h 13mMultiple Airlines
Fri 26/1212:01GSP - MAN
2 stops21h 19mMultiple Airlines
Deal found 1/12£1,044
Sat 13/1213:30MAN - GSP
1 stop12h 23mVirgin Atlantic
Fri 26/1210:05GSP - MAN
2 stops16h 50mVirgin Atlantic
Deal found 1/12£1,133
Sat 13/1209:50MAN - GSP
2 stops16h 55mAmerican Airlines
Fri 26/1216:00GSP - MAN
2 stops17h 20mAmerican Airlines
Deal found 1/12£1,144

Find flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 4 December 2025.

Round-trip from

£500

One-way from

£282

Popular in

August

Cheapest in

February

Average price

£961
16/1-23/1
  • 16/1-23/1
  • 4 total stops
  • 54h 13m total
  • Manchester to South Carolina
Search Deals
11/3
  • 11/3
  • 2 total stops
  • 34h 15m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (£44 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£16 potential savings vs. average return price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 December 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Fri 16/1

20:55-23:59

2 stops32h 04m

Charlotte Douglas

Fri 23/1

06:00-12:15

3 stops25h 15m

£531

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 25/3

06:00-23:30

2 stops21h 30m

Charleston

Mon 30/3

06:00-09:50

2 stops22h 50m

£625

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 29/4

10:35-23:43

2 stops18h 08m

Charleston

Thu 14/5

10:23-10:25

2 stops19h 02m

£638

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Sat 17/1

06:45-19:29

2 stops17h 44m

Greenville

Sat 24/1

12:04-10:30

2 stops17h 26m

£641

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Thu 26/2

06:00-18:12

2 stops17h 12m

Charleston

Mon 2/3

14:48-12:20

2 stops16h 32m

£642

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 25/2

06:00-19:23

2 stops18h 23m

Savannah/Hilton Head

Sun 1/3

19:20-12:20

2 stops36h 00m

£642

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Wed 25/2

06:00-14:23

2 stops37h 23m

Columbia Metropolitan

Sun 1/3

14:39-12:20

2 stops16h 41m

£642

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Sat 17/1

06:05-18:55

2 stops41h 50m

Columbia Metropolitan

Sat 24/1

14:49-17:00

2 stops21h 11m

£642

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Fri 16/1

06:25-19:29

2 stops18h 04m

Greenville

Fri 23/1

14:55-10:30

2 stops14h 35m

£642

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Thu 5/2

06:00-20:47

2 stops19h 47m

Greenville

Sun 8/2

14:55-12:20

2 stops16h 25m

£642

Flights are sorted by cheapest return flights first.

Deals found on 1/12

Showing 1-10 of 51 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £526). Flying from Manchester to South Carolina in June is currently the most expensive (average of £634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 4 December 2025.

It’s typically best to fly out from Manchester to South Carolina at midday. Doing so could potentially save you 16% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 4 December 2025.
See what other customers who have flown with Delta, KLM, andFinnair from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews
Check prices

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews
Check prices

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,428 reviews
Delta
7.9
Good
8,011 reviews
Check prices

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Finnair
7.6
Good
1,334 reviews
Delta
7.9
Good
8,011 reviews
Check prices

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Virgin Atlantic
7.5
Good
675 reviews
Delta
7.9
Good
8,011 reviews
Check prices

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,557 reviews
Delta
7.9
Good
8,011 reviews
Check prices

Comfort

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Manchester to South Carolina?

    Lufthansa, United Airlines, and Scandinavian Airlines can get you from Manchester to South Carolina in just under 17h 12m. Your travel time can differ by up to 4h 18m. Manchester and South Carolina are separated by a distance of 3948 mi. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Charleston or Manchester - Greenville, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £526). Flying from Manchester to South Carolina in June is currently the most expensive (average of £634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Manchester to South Carolina

Discover the top 6 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 December 2025.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£517Average£652FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£548Average£710FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£572Average£728FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£585Average£811FlexibilityNo cancel feeOn-time75%
Search KLM flights
DeltaCheapest£629Average£775FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Aer LingusCheapest£809Average£974FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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