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Cheap flights from Manchester to South Carolina from £287

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/9. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
23 Aug — 30 Aug1
1 adult

Cheap flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 18 August 2025.

Round-trip from

£573

One-way from

£287

Popular in

August

Cheapest in

February

Average price

£1,039
British Airways
  • British Airways
  • 29/9-6/10
  • 4 total stops
  • 29h 42m total
  • Manchester to South Carolina
Search Deals
22/9
  • 22/9
  • 2 total stops
  • 33h 55m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 8% potential increase in price (£54 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£19 potential savings vs. average return price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Manchester to South Carolina

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 August 2025.

Mon 29/908:00MAN - CHS
2 stops15h 42mBritish Airways
Mon 6/1018:15CHS - MAN
2 stops14h 00mBritish Airways
Deal found 15/8£573
Tue 30/916:05MAN - GSP
2 stops30h 47mBritish Airways
Tue 7/1013:35GSP - MAN
2 stops18h 35mBritish Airways
Deal found 16/8£573
Sat 6/1210:10MAN - CHS
2 stops39h 41mScandinavian Airlines
Thu 11/1217:55CHS - MAN
2 stops19h 40mScandinavian Airlines
Deal found 17/8£575
Tue 18/1107:40MAN - GSP
2 stops18h 14mBritish Airways
Wed 3/1211:11GSP - MAN
2 stops18h 44mBritish Airways
Deal found 16/8£578
Tue 30/912:35MAN - GSP
1 stop13h 32mVirgin Atlantic
Tue 7/1013:32GSP - MAN
1 stop14h 03mVirgin Atlantic
Deal found 16/8£579
Wed 1/1014:15MAN - CHS
1 stop13h 01mVirgin Atlantic
Wed 8/1018:55CHS - MAN
2 stops31h 40mVirgin Atlantic
Deal found 17/8£580
Mon 15/919:10MAN - MYR
2 stops33h 39mScandinavian Airlines
Fri 26/914:20MYR - MAN
2 stops20h 55mScandinavian Airlines
Deal found 16/8£580
Mon 29/912:35MAN - CHS
1 stop14h 58mVirgin Atlantic
Mon 6/1016:14CHS - MAN
1 stop11h 21mVirgin Atlantic
Deal found 15/8£583
Tue 2/911:55MAN - MYR
2 stops16h 54mVirgin Atlantic
Tue 9/918:56MYR - MAN
2 stops31h 39mVirgin Atlantic
Deal found 17/8£584
Tue 30/907:00MAN - CHS
2 stops17h 11mBritish Airways
Tue 7/1015:31CHS - MAN
2 stops16h 39mBritish Airways
Deal found 16/8£586
Sat 6/1213:30MAN - CHS
1 stop15h 11mVirgin Atlantic
Wed 10/1214:25CHS - MAN
1 stop15h 05mVirgin Atlantic
Deal found 17/8£600
Tue 30/909:10MAN - CAE
2 stops29h 39mUnited Airlines
Tue 7/1011:04CAE - MAN
2 stops17h 51mUnited Airlines
Deal found 16/8£602

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 August 2025.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 1/10

09:20-19:11

2 stops14h 51m

Charleston

Wed 8/10

17:34-13:10

2 stops14h 36m

£573

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Mon 29/9

08:00-18:42

2 stops15h 42m

Charleston

Mon 6/10

18:15-13:15

2 stops14h 00m

£573

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 30/9

16:05-17:52

2 stops30h 47m

Greenville

Tue 7/10

13:35-13:10

2 stops18h 35m

£573

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Sat 6/12

10:10-20:51

2 stops39h 41m

Charleston

Thu 11/12

17:55-18:35

2 stops19h 40m

£575

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Fri 5/12

19:15-22:04

2 stops31h 49m

Charleston

Thu 11/12

16:30-09:30

2 stops36h 00m

£575

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Sat 6/12

10:10-20:51

2 stops39h 41m

Charleston

Wed 10/12

06:00-18:35

2 stops31h 35m

£575

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 18/11

07:40-20:54

2 stops18h 14m

Greenville

Wed 3/12

11:11-10:55

2 stops18h 44m

£578

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 30/9

12:35-21:07

1 stop13h 32m

Greenville

Tue 7/10

13:32-08:35

1 stop14h 03m

£579

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 1/10

14:15-22:16

1 stop13h 01m

Charleston

Wed 8/10

18:55-07:35

2 stops31h 40m

£580

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Mon 15/9

19:10-23:49

2 stops33h 39m

Myrtle Beach Intl

Fri 26/9

14:20-16:15

2 stops20h 55m

£580

Flights are sorted by cheapest return flights first.

Deals found on 17/8

Showing 1-10 of 51 results
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6

Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAN to SC?

Find hourly flight availability from Manchester to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 18 August 2025.

When flying from Manchester to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Manchester to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 18 August 2025.
See what other customers who have flown with KLM, Finnair, andAir France from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,385 reviews
Check prices

Crew

8.4

Boarding

7.8

Food

7.3

Overall

7.8

Entertainment

7.1

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
KLM
7.8
Good
1,385 reviews
KLM
7.8
Good
1,385 reviews
Check prices

Crew

8.4

Boarding

7.8

Food

7.3

Overall

7.8

Entertainment

7.1

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Finnair
7.6
Good
1,320 reviews
KLM
7.8
Good
1,385 reviews
Check prices

Crew

8.4

Boarding

7.8

Food

7.3

Overall

7.8

Entertainment

7.1

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air France
7.4
Good
1,468 reviews
KLM
7.8
Good
1,385 reviews
Check prices

Crew

8.4

Boarding

7.8

Food

7.3

Overall

7.8

Entertainment

7.1

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Virgin Atlantic
7.4
Good
657 reviews
KLM
7.8
Good
1,385 reviews
Check prices

Crew

8.4

Boarding

7.8

Food

7.3

Overall

7.8

Entertainment

7.1

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
British Airways
6.7
Okay
7,277 reviews
KLM
7.8
Good
1,385 reviews
Check prices

Crew

8.4

Boarding

7.8

Food

7.3

Overall

7.8

Entertainment

7.1

Comfort

7.7

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Savannah/Hilton Head or Manchester - Charleston, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £731). Flying from Manchester to South Carolina in July is currently the most expensive (average of £970). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Manchester to South Carolina

Discover the top 8 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 August 2025.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£518Average£639FlexibilityNo cancel feeOn-time76%
Search Finnair flights
Air FranceCheapest£546Average£746FlexibilityNo cancel feeOn-time77%
Search Air France flights
British AirwaysCheapest£553Average£691FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£565Average£718FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£574Average£785FlexibilityNo cancel feeOn-time75%
Search KLM flights
American AirlinesCheapest£588Average£723FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest£616Average£738FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Aer LingusCheapest£775Average£942FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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