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Cheap flights from Manchester to South Carolina from £268

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/8. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
15 Aug — 22 Aug1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 July 2026.

Sat 29/809:35
MAN
-
SAV
2 stops17h 16m
Scandinavian Airlines
Sat 5/911:28
SAV
-
MAN
2 stops19h 17m
Scandinavian Airlines
Deal found 15/7£551
Wed 2/909:35
MAN
-
CLT
2 stops15h 59m
Scandinavian Airlines
Wed 30/910:40
CLT
-
MAN
2 stops20h 25m
Scandinavian Airlines
Deal found 14/7£564
Thu 1/1009:35
MAN
-
CLT
2 stops17h 28m
Scandinavian Airlines
Mon 5/1006:10
CLT
-
MAN
2 stops21h 45m
Scandinavian Airlines
Deal found 15/7£576
Fri 11/909:35
MAN
-
CLT
2 stops17h 33m
Scandinavian Airlines
Mon 21/917:02
CLT
-
MAN
2 stops20h 28m
Scandinavian Airlines
Deal found 15/7£577
Tue 20/1009:35
MAN
-
CLT
2 stops17h 28m
Scandinavian Airlines
Tue 3/1107:10
CLT
-
MAN
2 stops21h 20m
Scandinavian Airlines
Deal found 14/7£580
Sun 15/1119:15
MAN
-
CLT
2 stops32h 01m
Scandinavian Airlines
Thu 26/1113:15
CLT
-
MAN
2 stops24h 20m
Scandinavian Airlines
Deal found 15/7£586
Wed 2/921:10
MAN
-
CLT
2 stops30h 48m
Scandinavian Airlines
Sun 6/913:57
CLT
-
MAN
2 stops37h 58m
Scandinavian Airlines
Deal found 14/7£589
Mon 14/920:25
MAN
-
CLT
2 stops31h 19m
Scandinavian Airlines
Fri 25/914:25
CLT
-
MAN
2 stops23h 05m
Scandinavian Airlines
Deal found 13/7£590
Thu 12/1119:15
MAN
-
CLT
2 stops32h 01m
Scandinavian Airlines
Wed 25/1116:30
CLT
-
MAN
2 stops21h 05m
Scandinavian Airlines
Deal found 15/7£596
Thu 10/919:10
MAN
-
CLT
2 stops31h 58m
Scandinavian Airlines
Mon 14/906:07
CLT
-
MAN
2 stops45h 48m
Scandinavian Airlines
Deal found 13/7£601
Sat 24/1019:10
MAN
-
SAV
2 stops31h 16m
Scandinavian Airlines
Sun 1/1112:43
SAV
-
MAN
2 stops39h 47m
Scandinavian Airlines
Deal found 14/7£601
Tue 15/919:10
MAN
-
CLT
2 stops31h 53m
Scandinavian Airlines
Fri 25/906:07
CLT
-
MAN
2 stops45h 48m
Scandinavian Airlines
Deal found 13/7£603

Find flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 16 July 2026.

Round-trip from

£551

One-way from

£268

Popular in

July

Cheapest in

January

Average price

£949
Scandinavian Airlines
  • Scandinavian Airlines
  • 29/8-5/9
  • 4 total stops
  • 36h 33m total
  • Manchester to South Carolina
Search Deals
28/8
  • 28/8
  • 3 total stops
  • 41h 31m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£54 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£15 potential savings vs. average return price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 16 July 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Wed 2/9

21:10-22:58

2 stops30h 48m

Charlotte Douglas

Sun 6/9

13:57-08:55

2 stops37h 58m

£592

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Wed 18/11

19:15-22:16

2 stops32h 01m

Charlotte Douglas

Wed 25/11

16:30-18:35

2 stops21h 05m

£596

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Sat 29/8

09:35-21:51

2 stops17h 16m

Savannah/Hilton Head

Sat 5/9

11:28-18:50

3 stops26h 22m

£601

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Thu 10/9

19:10-22:08

2 stops31h 58m

Charlotte Douglas

Mon 14/9

06:07-08:55

2 stops45h 48m

£601

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 1/9

06:55-10:24

2 stops32h 29m

Greenville

Wed 23/9

07:47-09:50

2 stops21h 03m

£772

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 7/10

10:40-20:43

1 stop15h 03m

Charleston

Sun 11/10

19:10-08:25

2 stops32h 15m

£792

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Thu 1/10

07:45-19:29

2 stops16h 44m

Greenville

Mon 5/10

17:56-13:10

2 stops14h 14m

£800

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Thu 8/10

11:00-23:47

2 stops17h 47m

Columbia Metropolitan

Tue 3/11

12:00-06:40

2 stops13h 40m

£803

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Mon 31/8

13:55-22:38

2 stops37h 43m

Myrtle Beach Intl

Tue 8/9

12:14-08:50

2 stops15h 36m

£804

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Tue 1/9

05:55-21:26

2 stops20h 31m

Greenville

Wed 23/9

05:45-07:15

1 stop20h 30m

£805

Flights are sorted by cheapest return flights first.

Deals found on 15/7

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, June is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £457). Flying from Manchester to South Carolina in July is currently the most expensive (average of £771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 16 July 2026.
See what other customers who have flown with KLM,Delta, andVirgin Atlantic from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,539 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.7

Entertainment

7.2

Crew

8.4

Overall

7.8

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
KLM
7.8
Good
1,539 reviews
KLM
7.8
Good
1,539 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.7

Entertainment

7.2

Crew

8.4

Overall

7.8

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Delta
7.8
Good
8,472 reviews
KLM
7.8
Good
1,539 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.7

Entertainment

7.2

Crew

8.4

Overall

7.8

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
Virgin Atlantic
7.5
Good
693 reviews
KLM
7.8
Good
1,539 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.7

Entertainment

7.2

Crew

8.4

Overall

7.8

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
American Airlines
7.1
Good
11,818 reviews
KLM
7.8
Good
1,539 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.7

Entertainment

7.2

Crew

8.4

Overall

7.8

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful
British Airways
6.7
Okay
8,120 reviews
KLM
7.8
Good
1,539 reviews
Check prices

Boarding

7.8

Food

7.3

Comfort

7.7

Entertainment

7.2

Crew

8.4

Overall

7.8

Reviews

1 / 20
6.0
Good

Anonymous,Apr 2026

OKC - ATL

Flight was ok - difficult as I had seat next to bathroom.. Food awful

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Manchester to South Carolina?

    Scandinavian Airlines, British Airways, and KLM can get you from Manchester to South Carolina in just under 15h 03m. Your travel time can differ by up to 17h 26m. Manchester and South Carolina are separated by a distance of 3948 mi. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Savannah/Hilton Head or Manchester - Columbia Metropolitan, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, June is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £457). Flying from Manchester to South Carolina in July is currently the most expensive (average of £771). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Manchester to South Carolina

Discover the top 5 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 16 July 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£541Average£747FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£555Average£771FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£597Average£752FlexibilityNo cancel feeOn-time75%
Search KLM flights
American AirlinesCheapest£621Average£672FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest£659Average£806FlexibilityNo cancel feeOn-timeN/A
Search Delta flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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