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Cheap flights from Manchester to South Carolina from £271

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 29/5. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
10 May — 17 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 April 2026.

Wed 13/506:35
MAN
-
CLT
3 stops34h 08m
Multiple Airlines
Wed 27/507:12
CLT
-
MAN
3 stops23h 08m
Multiple Airlines
Deal found 7/4£650
Thu 14/521:10
MAN
-
CLT
2 stops30h 37m
Scandinavian Airlines
Thu 28/506:03
CLT
-
MAN
2 stops25h 02m
Scandinavian Airlines
Deal found 7/4£655
Mon 5/1020:25
MAN
-
CLT
2 stops30h 51m
Scandinavian Airlines
Thu 8/1010:00
CLT
-
MAN
2 stops21h 05m
Scandinavian Airlines
Deal found 8/4£678
Thu 14/521:10
MAN
-
CLT
2 stops30h 37m
Scandinavian Airlines
Thu 4/606:03
CLT
-
MAN
2 stops25h 02m
Scandinavian Airlines
Deal found 7/4£686
Fri 22/509:35
MAN
-
CLT
2 stops18h 19m
Scandinavian Airlines
Sat 30/506:00
CLT
-
MAN
2 stops45h 55m
Scandinavian Airlines
Deal found 9/4£694
Wed 13/509:35
MAN
-
CLT
2 stops17h 31m
Scandinavian Airlines
Wed 27/506:10
CLT
-
MAN
2 stops31h 20m
Scandinavian Airlines
Deal found 7/4£697
Sun 12/419:30
MAN
-
CLT
2 stops31h 41m
Scandinavian Airlines
Tue 28/414:30
CLT
-
MAN
2 stops23h 00m
Scandinavian Airlines
Deal found 9/4£701
Fri 8/520:25
MAN
-
SAV
2 stops30h 08m
Scandinavian Airlines
Fri 5/611:43
SAV
-
MAN
2 stops17h 17m
Scandinavian Airlines
Deal found 7/4£707
Fri 22/509:35
MAN
-
CLT
2 stops18h 19m
Scandinavian Airlines
Fri 29/514:14
CLT
-
MAN
2 stops37h 41m
Scandinavian Airlines
Deal found 7/4£710
Tue 5/508:10
MAN
-
GSP
2 stops19h 55m
Multiple Airlines
Tue 12/512:07
GSP
-
MAN
2 stops27h 18m
Multiple Airlines
Deal found 7/4£710
Sun 24/520:55
MAN
-
SAV
2 stops31h 57m
Multiple Airlines
Sun 31/519:15
SAV
-
MAN
2 stops20h 10m
Multiple Airlines
Deal found 9/4£724
Thu 16/408:10
MAN
-
CHS
2 stops20h 49m
Multiple Airlines
Thu 4/611:18
CHS
-
MAN
2 stops28h 07m
Multiple Airlines
Deal found 5/4£730

Find flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 10 April 2026.

Round-trip from

£650

One-way from

£271

Popular in

July

Cheapest in

January

Average price

£728
13/5-27/5
  • 13/5-27/5
  • 6 total stops
  • 57h 16m total
  • Manchester to South Carolina
Search Deals
29/5
  • 29/5
  • 2 total stops
  • 38h 33m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (£81 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£14 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 April 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Mon 5/10

09:35-22:23

2 stops17h 48m

Charlotte Douglas

Thu 8/10

10:00-08:55

3 stops17h 55m

£753

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Wed 6/5

06:05-23:59

2 stops22h 54m

Columbia Metropolitan

Wed 13/5

19:38-23:15

2 stops22h 37m

£779

ManchesterColumbia

MAN - CAE

MANCAE

Manchester

Wed 6/5

10:40-19:29

1 stop13h 49m

Columbia Metropolitan

Wed 13/5

11:56-08:15

2 stops15h 19m

£780

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Mon 4/5

06:00-17:13

2 stops16h 13m

Myrtle Beach Intl

Mon 11/5

15:14-10:25

2 stops14h 11m

£799

ManchesterGreenville

MAN - GSP

MANGSP

Manchester

Thu 7/5

05:55-09:58

2 stops33h 03m

Greenville

Thu 14/5

06:00-10:25

2 stops23h 25m

£805

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Tue 14/7

13:00-23:55

1 stop15h 55m

Myrtle Beach Intl

Tue 21/7

16:16-08:50

1 stop11h 34m

£818

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Wed 29/4

21:10-22:49

2 stops30h 39m

Charlotte Douglas

Sun 3/5

06:00-08:55

2 stops45h 55m

£819

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Mon 4/5

05:55-17:11

2 stops16h 16m

Savannah/Hilton Head

Thu 14/5

07:15-08:20

1 stop20h 05m

£821

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Sat 9/5

13:15-23:40

1 stop15h 25m

Savannah/Hilton Head

Thu 14/5

11:43-08:20

1 stop15h 37m

£837

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Sun 24/5

20:00-20:01

2 stops29h 01m

Myrtle Beach Intl

Sun 31/5

20:41-08:50

2 stops31h 09m

£839

Flights are sorted by cheapest return flights first.

Deals found on 9/4

Showing 1-10 of 51 resultsSorted by cheapest first
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2
3
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6

Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, March is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £534). Flying from Manchester to South Carolina in July is currently the most expensive (average of £671). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 10 April 2026.
See what other customers who have flown with Delta,KLM, andVirgin Atlantic from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,400 reviews
Check prices

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,400 reviews
Delta
7.9
Good
8,400 reviews
Check prices

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,493 reviews
Delta
7.9
Good
8,400 reviews
Check prices

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Virgin Atlantic
7.5
Good
685 reviews
Delta
7.9
Good
8,400 reviews
Check prices

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,564 reviews
Delta
7.9
Good
8,400 reviews
Check prices

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,869 reviews
Delta
7.9
Good
8,400 reviews
Check prices

Boarding

8.1

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Manchester to South Carolina?

    Scandinavian Airlines, Lufthansa, and Virgin Atlantic can get you from Manchester to South Carolina in just under 13h 49m. Your travel time can differ by up to 9h 05m. Manchester and South Carolina are separated by a distance of 3940 mi. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Savannah/Hilton Head or Manchester - Charleston, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, March is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £534). Flying from Manchester to South Carolina in July is currently the most expensive (average of £671). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Manchester to South Carolina

Discover the top 5 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 10 April 2026.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest£538Average£684FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£567Average£753FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£599Average£776FlexibilityNo cancel feeOn-time75%
Search KLM flights
American AirlinesCheapest£623Average£674FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapest£661Average£808FlexibilityNo cancel feeOn-timeN/A
Search Delta flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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