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Cheap flights from Manchester to South Carolina from £271

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAN — CHS
6 Feb — 13 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Manchester to South Carolina

Keep the following information in mind while searching for Manchester to South Carolina flight deals. Data was last updated 7 January 2026.

Round-trip from

£528

One-way from

£271

Popular in

August

Cheapest in

February

Average price

£634
20/2-27/2
  • 20/2-27/2
  • 4 total stops
  • 44h 03m total
  • Manchester to South Carolina
Search Deals
24/2
  • 24/2
  • 3 total stops
  • 50h 27m total
  • Manchester to South Carolina
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£57 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£18 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Find flight deals from Manchester to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Manchester to South Carolina
Explore the most affordable flight options available from Manchester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 7 January 2026.

Fri 20/206:05MAN - MYR
2 stops22h 52mMultiple Airlines
Fri 27/210:09MYR - MAN
2 stops21h 11mMultiple Airlines
Deal found 6/1£528
Thu 19/211:15MAN - CLT
2 stops17h 44mMultiple Airlines
Thu 26/209:21CLT - MAN
2 stops26h 39mMultiple Airlines
Deal found 5/1£539
Tue 13/115:50MAN - CLT
3 stops37h 09mMultiple Airlines
Tue 20/119:43CLT - MAN
3 stops36h 42mMultiple Airlines
Deal found 6/1£540
Thu 19/209:25MAN - MYR
2 stops19h 32mMultiple Airlines
Thu 26/210:09MYR - MAN
3 stops19h 11mMultiple Airlines
Deal found 5/1£563
Tue 13/115:50MAN - MYR
3 stops34h 14mMultiple Airlines
Tue 27/121:59MYR - MAN
3 stops31h 46mMultiple Airlines
Deal found 6/1£567
Sat 18/417:00MAN - CLT
3 stops32h 33mMultiple Airlines
Mon 4/509:20CLT - MAN
2 stops23h 30mMultiple Airlines
Deal found 6/1£569
Fri 24/420:25MAN - CLT
2 stops31h 24mScandinavian Airlines
Sat 9/510:00CLT - MAN
2 stops20h 45mScandinavian Airlines
Deal found 6/1£577
Tue 13/115:50MAN - MYR
3 stops34h 14mMultiple Airlines
Tue 20/115:39MYR - MAN
2 stops14h 06mMultiple Airlines
Deal found 6/1£580
Tue 13/107:40MAN - MYR
2 stops16h 09mFinnair
Tue 20/119:19MYR - MAN
2 stops16h 11mFinnair
Deal found 6/1£583
Wed 18/206:10MAN - SAV
2 stops19h 45mIberia
Wed 25/319:34SAV - MAN
2 stops16h 46mIberia
Deal found 5/1£583
Wed 29/410:40MAN - CHS
1 stop14h 59mVirgin Atlantic
Thu 14/506:00CHS - MAN
1 stop21h 20mVirgin Atlantic
Deal found 5/1£587
Mon 23/219:15MAN - CLT
2 stops31h 42mScandinavian Airlines
Mon 9/310:15CLT - MAN
2 stops19h 15mScandinavian Airlines
Deal found 5/1£588

Cheapflights Fare Finder

 
Customise your flight search to find flights from Manchester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 7 January 2026.
Use the filters below to find and compare flights from Manchester to South Carolina that are best for you.

Fly from

Manchester

Fly to

South Carolina

Route

Depart

Return

Price

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Fri 20/2

06:05-23:57

2 stops22h 52m

Myrtle Beach Intl

Fri 27/2

10:09-12:20

2 stops21h 11m

£528

ManchesterMyrtle Beach

MAN - MYR

MANMYR

Manchester

Thu 19/2

09:25-23:57

2 stops19h 32m

Myrtle Beach Intl

Thu 26/2

10:09-10:20

3 stops19h 11m

£563

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Sat 18/4

17:00-20:33

3 stops32h 33m

Charlotte Douglas

Mon 4/5

09:20-13:50

2 stops23h 30m

£569

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Fri 24/4

20:25-22:49

2 stops31h 24m

Charlotte Douglas

Sat 9/5

10:00-11:45

2 stops20h 45m

£577

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 18/2

06:10-20:55

2 stops19h 45m

Savannah/Hilton Head

Wed 25/3

19:34-16:20

2 stops16h 46m

£583

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 29/4

10:40-20:39

1 stop14h 59m

Charleston

Thu 14/5

06:00-08:20

1 stop21h 20m

£587

ManchesterCharlotte

MAN - CLT

MANCLT

Manchester

Wed 22/4

21:10-22:49

2 stops30h 39m

Charlotte Douglas

Thu 7/5

06:00-08:55

2 stops21h 55m

£589

ManchesterCharleston

MAN - CHS

MANCHS

Manchester

Wed 29/4

10:55-22:53

2 stops16h 58m

Charleston

Thu 14/5

12:27-11:35

2 stops18h 08m

£596

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Wed 18/2

13:00-23:57

1 stop15h 57m

Savannah/Hilton Head

Wed 25/3

13:47-10:30

1 stop16h 43m

£605

ManchesterSavannah

MAN - SAV

MANSAV

Manchester

Fri 20/2

06:05-19:23

2 stops18h 18m

Savannah/Hilton Head

Fri 27/2

19:20-14:50

2 stops14h 30m

£613

Flights are sorted by cheapest return flights first.

Deals found on 5/1

Showing 1-10 of 44 results
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Best time to book a flight from Manchester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Manchester with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to South Carolina

What is the cheapest month to book a flight from Manchester to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £517). Flying from Manchester to South Carolina in June is currently the most expensive (average of £623). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Manchester to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 7 January 2026.
See what other customers who have flown with Delta, KLM, andFinnair from Manchester to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,017 reviews
Check prices

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,017 reviews
Delta
7.9
Good
8,017 reviews
Check prices

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
KLM
7.7
Good
1,434 reviews
Delta
7.9
Good
8,017 reviews
Check prices

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Finnair
7.6
Good
1,345 reviews
Delta
7.9
Good
8,017 reviews
Check prices

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Virgin Atlantic
7.5
Good
678 reviews
Delta
7.9
Good
8,017 reviews
Check prices

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
British Airways
6.7
Okay
7,657 reviews
Delta
7.9
Good
8,017 reviews
Check prices

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Manchester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Manchester to South Carolina?

    For a flight from Manchester to South Carolina, you will be flying from Manchester. Manchester (MAN) is just 8.9 mi from the center of the city.

  • How long is the flight from Manchester to South Carolina?

    Scandinavian Airlines, Iberia, and Virgin Atlantic can get you from Manchester to South Carolina in just under 14h 59m. Your travel time can differ by up to 16h 25m. Manchester and South Carolina are separated by a distance of 3948 mi. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most popular routes from Manchester to South Carolina?

    While some choose either Manchester - Myrtle Beach Intl or Manchester - Charleston, Manchester - Charlotte Douglas is the most popular route from Manchester to South Carolina.

  • Can I find deals for flights from Manchester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Manchester to South Carolina flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Manchester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to South Carolina.

  • Can I find deals for business class flights from Manchester to South Carolina?

    Yes. Cheapflights offers flight deals from Manchester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Manchester to South Carolina (average of £517). Flying from Manchester to South Carolina in June is currently the most expensive (average of £623). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Manchester to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Manchester to South Carolina

Discover the top 6 airlines that operate flights from Manchester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 7 January 2026.
AirlineCheapestAverageFlexibilityOn-time
FinnairCheapest£529Average£621FlexibilityNo cancel feeOn-time76%
Search Finnair flights
British AirwaysCheapest£539Average£696FlexibilityNo cancel feeOn-time70%
Search British Airways flights
Virgin AtlanticCheapest£562Average£719FlexibilityNo cancel feeOn-time72%
Search Virgin Atlantic flights
KLMCheapest£575Average£749FlexibilityNo cancel feeOn-time75%
Search KLM flights
DeltaCheapest£618Average£775FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
Aer LingusCheapest£795Average£956FlexibilityNo cancel feeOn-timeN/A
Search Aer Lingus flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Manchester to South Carolina?

Deals for Manchester to South Carolina flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Manchester to South Carolina?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Manchester to South Carolina.

Can Cheapflights find flights from Manchester to South Carolina with no change fees?

Yes! Cheapflights helps users easily find flights from Manchester to South Carolina with no change fees.

Can Cheapflights notify me if prices for flights from Manchester to South Carolina become cheaper?

Of course! You can now track prices for flights from Manchester to South Carolina and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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