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Cheap flights from Southampton to Key Largo from £552

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — MIA
3 Jun — 10 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Key Largo

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Key Largo
Explore the most affordable flight options available from Southampton to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 4 May 2026.

Mon 31/817:20
SOU
-
MIA
1 stop26h 25m
Delta
Tue 8/916:55
MIA
-
SOU
1 stop18h 55m
Delta
Deal found 29/4£674
Tue 3/1117:30
SOU
-
MIA
2 stops28h 03m
Delta
Wed 11/1111:35
MIA
-
SOU
2 stops15h 45m
Delta
Deal found 3/5£682
Mon 31/817:20
SOU
-
MIA
1 stop26h 25m
Delta
Fri 11/907:00
MIA
-
SOU
2 stops20h 45m
Delta
Deal found 29/4£705
Thu 5/1117:30
SOU
-
MIA
2 stops28h 03m
Delta
Wed 11/1112:05
MIA
-
SOU
2 stops15h 15m
Delta
Deal found 3/5£712
Mon 31/817:20
SOU
-
MIA
1 stop26h 25m
Delta
Mon 7/911:35
MIA
-
SOU
2 stops16h 00m
Delta
Deal found 29/4£734
Wed 28/1009:20
SOU
-
MIA
1 stop12h 50m
British Airways
Wed 18/1119:05
MIA
-
SOU
1 stop19h 25m
British Airways
Deal found 29/4£736
Sun 30/817:30
SOU
-
MIA
2 stops28h 52m
Delta
Wed 9/911:35
MIA
-
SOU
2 stops16h 00m
Delta
Deal found 29/4£738
Thu 5/1117:30
SOU
-
MIA
2 stops28h 03m
Delta
Sat 14/1111:35
MIA
-
SOU
2 stops16h 15m
Delta
Deal found 3/5£741
Fri 28/818:05
SOU
-
MIA
1 stop25h 40m
Delta
Tue 8/916:55
MIA
-
SOU
1 stop18h 55m
Delta
Deal found 29/4£764
Sat 24/1017:20
SOU
-
MIA
1 stop27h 40m
Delta
Tue 3/1117:00
MIA
-
SOU
1 stop19h 00m
Delta
Deal found 3/5£768
Sun 8/1109:20
SOU
-
MIA
1 stop12h 50m
British Airways
Wed 11/1119:05
MIA
-
SOU
1 stop16h 30m
British Airways
Deal found 3/5£770

Find flight deals from Southampton to Key Largo

Keep the following information in mind while searching for Southampton to Key Largo flight deals. Data was last updated 4 May 2026.

Round-trip from

£674

One-way from

£552

Popular in

December

Cheapest in

September

Average price

£493
Delta
  • Delta
  • 31/8-9/9
  • 3 total stops
  • 42h 25m total
  • Southampton to Key Largo
Search Deals
7/8
  • 7/8
  • 3 total stops
  • 33h 55m total
  • Southampton to Key Largo
Search Deals
Highest demand for flights based on searches. 0% potential increase in price (£3 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£8 potential savings vs. average return price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 4 May 2026.
Use the filters below to find and compare flights from Southampton to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 23/10

09:05-00:52

2 stops20h 47m

Miami

Tue 3/11

17:00-17:00

1 stop19h 00m

£772

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 22/10

09:05-23:09

2 stops19h 04m

Miami

Wed 4/11

19:30-17:00

2 stops16h 30m

£772

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Tue 1/9

19:55-14:30

2 stops23h 35m

Miami

Tue 22/9

22:40-19:25

2 stops15h 45m

£780

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Mon 15/6

09:05-23:21

2 stops19h 16m

Miami

Mon 22/6

07:05-08:35

2 stops20h 30m

£810

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 13/6

09:15-10:21

2 stops30h 06m

Miami

Mon 29/6

07:05-08:35

2 stops20h 30m

£832

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 2/7

09:05-23:21

2 stops19h 16m

Miami

Mon 13/7

11:30-08:45

2 stops16h 15m

£832

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Fri 29/5

17:20-17:41

2 stops29h 21m

Miami

Tue 2/6

11:10-08:35

2 stops16h 25m

£833
Fastest return journey

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 2/7

09:05-23:21

2 stops19h 16m

Miami

Tue 14/7

16:55-08:45

1 stop10h 50m

£833

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Thu 2/7

09:05-23:21

2 stops19h 16m

Miami

Fri 17/7

14:09-08:45

2 stops13h 36m

£863

SouthamptonMiami

SOU - MIA

SOUMIA

Southampton Eastleigh

Sat 16/5

17:20-14:45

1 stop26h 25m

Miami

Thu 28/5

11:58-08:35

2 stops15h 37m

£865

Flights are sorted by cheapest return flights first.

Deals found on 30/4

Showing 1-10 of 24 resultsSorted by cheapest first
1
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3

Best time to book a flight from Southampton to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Key Largo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Southampton to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Southampton to Key Largo?

    Southampton Eastleigh (SOU), located 3.5 mi from the city center, is the airport you fly out of when you book flights from Southampton to Key Largo. 0 airlines have flights from Eastleigh to Key Largo on a regular basis. Booking flights from Southampton Eastleigh to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Southampton to Key Largo?

    A quick flight from Southampton to Key Largo can take about 20h 47m. Delta provides one of the quickest options available for as low as £772. There are 4381 mi between Southampton and Key Largo. This flight may include one or multiple stops.

  • Can I find deals for flights from Southampton to Key Largo that include hotel bookings?

    Yes. In addition to deals on Southampton to Key Largo flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Key Largo.

  • Can I find deals for business class flights from Southampton to Key Largo?

    Yes. Cheapflights offers flight deals from Southampton to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Fly with Cheapflights

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How does Cheapflights help users find flights from Southampton to Key Largo?

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Can Cheapflights find flights from Southampton to Key Largo with no change fees?

Yes, we can. To see specific flights from Southampton to Key Largo with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Southampton to Key Largo become cheaper?

Yes! Start tracking prices for Southampton to Key Largo flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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