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Cheap flights from Southampton to San Francisco from £450

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 30/9. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — SFO
18 May — 25 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to San Francisco

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to San Francisco
Explore the most affordable flight options available from Southampton to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 April 2026.

Tue 2/609:20
SOU
-
SFO
2 stops23h 58m
Aer Lingus
Tue 9/617:40
SFO
-
SOU
1 stop17h 50m
Aer Lingus
Deal found 18/4£683
Wed 6/509:05
SOU
-
SFO
2 stops21h 42m
Delta
Wed 13/506:15
SFO
-
SOU
2 stops18h 20m
Delta
Deal found 18/4£701
Wed 6/509:20
SOU
-
SFO
1 stop14h 35m
Aer Lingus
Wed 13/517:40
SFO
-
SOU
1 stop17h 50m
Aer Lingus
Deal found 15/4£703
Wed 25/1109:20
SOU
-
SFO
1 stop14h 15m
British Airways
Sun 29/1118:20
SFO
-
SOU
1 stop14h 15m
British Airways
Deal found 17/4£749
Tue 2/609:20
SOU
-
SFO
2 stops23h 58m
Multiple Airlines
Tue 9/613:56
SFO
-
SOU
2 stops21h 34m
Multiple Airlines
Deal found 18/4£751
Mon 1/609:20
SOU
-
SFO
2 stops22h 49m
Aer Lingus
Mon 8/617:35
SFO
-
SOU
1 stop17h 55m
Aer Lingus
Deal found 17/4£754

Find flight deals from Southampton to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 April 2026.

Round-trip from

£683

One-way from

£450

Popular in

December

Cheapest in

February

Average price

£484
Aer Lingus
  • Aer Lingus
  • 2/6-9/6
  • 3 total stops
  • 41h 48m total
  • Southampton to San Francisco
Search Deals
British Airways
  • British Airways
  • 30/9
  • 1 total stop
  • 14h 35m total
  • Southampton to San Francisco
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£19 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£9 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 April 2026.
Use the filters below to find and compare flights from Southampton to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Tue 9/6

09:20-15:55

1 stop14h 35m

San Francisco

Thu 3/9

17:35-16:50

1 stop15h 15m

£822

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 2/7

09:05-22:35

2 stops21h 30m

San Francisco

Wed 15/7

14:19-17:35

2 stops19h 16m

£842

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 2/7

09:05-22:35

2 stops21h 30m

San Francisco

Tue 14/7

15:27-17:35

2 stops18h 08m

£842

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sun 7/6

20:00-15:50

1 stop27h 50m

San Francisco

Thu 3/9

19:30-09:45

2 stops30h 15m

£850

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 8/6

09:20-15:50

1 stop14h 30m

San Francisco

Fri 4/9

17:35-16:50

1 stop15h 15m

£851

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 2/7

09:20-15:50

1 stop14h 30m

San Francisco

Sun 12/7

16:35-19:25

2 stops18h 50m

£857

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Fri 29/5

06:50-17:40

2 stops18h 50m

San Francisco

Sun 7/6

17:40-19:30

1 stop17h 50m

£896
Fastest return journey

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Thu 16/7

09:20-15:50

1 stop14h 30m

San Francisco

Sun 9/8

17:40-16:50

1 stop15h 10m

£909

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Sat 4/7

09:20-15:55

1 stop14h 35m

San Francisco

Tue 14/7

17:40-16:50

1 stop15h 10m

£923
Cheapest one-way
Fastest single journey

SouthamptonSan Francisco

SOU - SFO

SOUSFO

Southampton Eastleigh

Mon 8/6

09:20-15:50

1 stop14h 30m

£499

Flights are sorted by cheapest return flights first.

Deals found on 14/4

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Southampton to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Southampton to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Southampton to San Francisco?

    British Airways and Delta can get you from Southampton to San Francisco in just under 14h 35m. Your travel time can differ by up to 6h 55m. Southampton and San Francisco are separated by a distance of 5349 mi. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Southampton to San Francisco that include hotel bookings?

    Yes. In addition to deals on Southampton to San Francisco flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to San Francisco.

  • Can I find deals for business class flights from Southampton to San Francisco?

    Yes. Cheapflights offers flight deals from Southampton to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Travelling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Newark
San Bruno
Bodega Bay
South San Francisco
Sunnyvale

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Southampton to San Francisco

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to San Francisco?

Cheapflights helps you search for flights from Southampton to San Francisco via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Southampton to San Francisco?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Southampton to San Francisco.

Can Cheapflights find flights from Southampton to San Francisco with no change fees?

Need flexible booking options for your flight to San Francisco from Southampton? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Southampton to San Francisco become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to San Francisco from Southampton today and book when prices fit your budget.

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