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Cheap flights from Southampton to Chicago O'Hare Intl Airport from £331

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/4. Fares are subject to change and may not be available on all flights or dates of travel.
SOU — ORD
21 Feb — 28 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to O'Hare Intl

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to O'Hare Intl
Explore the most affordable flight options available from Southampton to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 January 2026.

Wed 28/112:25
SOU
-
ORD
1 stop12h 50m
British Airways
Sun 1/221:00
ORD
-
SOU
1 stop32h 55m
British Airways
Deal found 19/1£498
Thu 23/409:10
SOU
-
ORD
1 stop16h 05m
British Airways
Sun 26/415:45
ORD
-
SOU
1 stop10h 55m
British Airways
Deal found 21/1£508
Sun 8/309:30
SOU
-
ORD
1 stop14h 25m
British Airways
Sun 15/316:50
ORD
-
SOU
1 stop10h 55m
British Airways
Deal found 21/1£531
Sat 7/309:25
SOU
-
ORD
1 stop10h 55m
Virgin Atlantic
Sat 14/317:25
ORD
-
SOU
1 stop10h 25m
Virgin Atlantic
Deal found 21/1£545
Mon 23/320:10
SOU
-
ORD
2 stops27h 10m
Multiple Airlines
Sun 29/315:45
ORD
-
SOU
1 stop10h 55m
Multiple Airlines
Deal found 19/1£552
Mon 23/308:50
SOU
-
ORD
1 stop11h 30m
Virgin Atlantic
Sun 29/316:20
ORD
-
SOU
1 stop18h 30m
Virgin Atlantic
Deal found 19/1£599

Find flight deals from Southampton to O'Hare Intl

Discover tips and strategies to find the most affordable flight options for your journey from Southampton (SOU) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 22 January 2026.

Round-trip from

£491

One-way from

£331

Popular in

July

Cheapest in

February

Average price

£465
British Airways
  • British Airways
  • 1/3-17/3
  • 2 total stops
  • 29h 40m total
  • Southampton to Chicago
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21/4
  • 21/4
  • 3 total stops
  • 38h 40m total
  • Southampton to Chicago
Search Deals
Highest demand for flights based on searches. 14% potential increase in price (£65 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (£10 potential savings vs. average return price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Southampton to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 22 January 2026.
Use the filters below to find and compare flights from Southampton to Chicago O'Hare Intl Airport that are best for you.

Fly from

Southampton

Fly to

O'Hare Intl

Route

Depart

Return

Price

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Thu 23/4

09:10-19:15

1 stop16h 05m

Chicago O'Hare Intl

Sun 26/4

15:45-08:40

1 stop10h 55m

£508

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Sun 8/3

09:30-18:55

1 stop14h 25m

Chicago O'Hare Intl

Sun 15/3

16:50-08:45

1 stop10h 55m

£531

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Mon 23/3

20:10-18:20

2 stops27h 10m

Chicago O'Hare Intl

Sun 29/3

15:45-08:40

1 stop10h 55m

£552

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Mon 23/3

08:50-15:20

1 stop11h 30m

Chicago O'Hare Intl

Sun 29/3

16:20-16:50

1 stop18h 30m

£599

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Sat 7/3

09:25-14:20

1 stop10h 55m

Chicago O'Hare Intl

Sat 14/3

17:59-17:05

2 stops42h 06m

£613

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Sat 7/3

17:30-22:54

2 stops35h 24m

Chicago O'Hare Intl

Sat 14/3

17:59-17:05

2 stops42h 06m

£675

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Tue 21/4

09:10-17:50

3 stops38h 40m

£331

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Tue 5/5

18:10-23:12

3 stops35h 02m

£335

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Tue 21/4

09:10-19:15

1 stop16h 05m

£374

SouthamptonChicago

SOU - ORD

SOUORD

Southampton Eastleigh

Tue 5/5

20:00-19:15

1 stop29h 15m

£435

Flights are sorted by cheapest return flights first.

Deals found on 20/1

Showing 1-10 of 15 results
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Best time to book a flight from Southampton to O'Hare Intl

Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Southampton with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Southampton to Chicago O'Hare Intl Airport

What is the cheapest month to book a flight from Southampton to Chicago O'Hare Intl Airport?

Currently, April is the cheapest month in which you can book a flight from Southampton to Chicago O'Hare Intl Airport (average of £121). Flying from Southampton to Chicago O'Hare Intl Airport in July is currently the most expensive (average of £501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Southampton to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Southampton to Chicago O'Hare Intl?

    Southampton Eastleigh (SOU) is the airport you will fly out of if you book a flight from Southampton to Chicago O'Hare Intl. You should not have trouble finding flights to Chicago O'Hare Intl from Eastleigh; the airport handles an average of 0 outbound flights to Chicago O'Hare Intl per day. You should also have plenty of airline options to choose from since 0 airlines have flights from the Southampton airport to Chicago O'Hare Intl. It is only a 3.5 mi journey to Eastleigh (SOU) from Southampton’s city center.

  • How long is the flight from Southampton to Chicago O'Hare Intl Airport?

    For as low as £599, British Airways can have you in Chicago O'Hare Intl Airport from Southampton in 11h 30m. Airlines will cover a distance of 3921 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Southampton to O'Hare Intl that include hotel bookings?

    Yes. In addition to deals on Southampton to O'Hare Intl flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to O'Hare Intl?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to O'Hare Intl.

  • Can I find deals for business class flights from Southampton to O'Hare Intl?

    Yes. Cheapflights offers flight deals from Southampton to O'Hare Intl by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Southampton to Chicago O'Hare Intl Airport?

    Currently, April is the cheapest month in which you can book a flight from Southampton to Chicago O'Hare Intl Airport (average of £121). Flying from Southampton to Chicago O'Hare Intl Airport in July is currently the most expensive (average of £501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Chicago O'Hare Intl Airport?

Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locations
Elk Grove Village

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Alternative routes for Southampton to O'Hare Intl

See prices for flight routes from nearby airports that may be better suited for you.
Heathrow to O'Hare Intl flights
Gatwick to O'Hare Intl flights
Heathrow to Midway flights
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Manchester to Midway flights
Edinburgh to Midway flights
Birmingham to O'Hare Intl flights
Gatwick to Midway flights
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Birmingham to Midway flights
Norwich to O'Hare Intl flights
Newcastle upon Tyne to O'Hare Intl flights
Leeds to Midway flights
Bristol to O'Hare Intl flights
Liverpool to O'Hare Intl flights
Southend to O'Hare Intl flights
Bristol to Midway flights
Newcastle upon Tyne to Midway flights
London City to Midway flights
Newquay to O'Hare Intl flights
Exeter to O'Hare Intl flights
Darlington to O'Hare Intl flights
Darlington to Midway flights
Southampton to Midway flights
Grimsby to O'Hare Intl flights
Doncaster to O'Hare Intl flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Southampton to O'Hare Intl?

When you search for this flight from Southampton to O'Hare Intl, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Southampton to O'Hare Intl?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Southampton to O'Hare Intl for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Southampton to O'Hare Intl with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Southampton to O'Hare Intl, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Southampton to O'Hare Intl become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to O'Hare Intl from Southampton today and book when prices fit your budget.

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