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Cheap flights from Southampton to Key West from £630

SOU — EYW
8 Oct — 15 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Southampton to Key West

Enter your travel dates to find the best prices.

Cheapest flights from Southampton to Key West

Wed 21/1009:15 -
2 stops37h 00m
Wed 28/1007:40 -
2 stops20h 30m
Deal found 6/9£630
Tue 15/917:20 -
2 stops31h 40m
Mon 28/918:19 -
2 stops33h 26m
Deal found 7/9£786
Tue 15/909:05 -
2 stops39h 55m
Mon 28/907:40 -
2 stops19h 55m
Deal found 8/9£808
Tue 15/920:00 -
3 stops28h 17m
Mon 28/919:47 -
3 stops18h 43m
Deal found 7/9£996

Find flight deals from Southampton to Key West

Round-trip from

£630

Popular in

June

Cheapest in

September

Average price

£529
KLM
  • KLM
  • 21/10-28/10
  • 4 total stops
  • 57h 30m total
  • Southampton to Key West
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Highest demand for flights based on searches. 7% potential increase in price (£40 potential increase over avg. return price).
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Cheapest flight prices on average. 2% potential price decrease (£13 potential savings vs. average return price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Southampton to Key West that are best for you.

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Route

Depart

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Price

Cheapest return flight
Fastest return journey

SouthamptonKey West

SOU Southampton Eastleigh - EYW Key West

SOUEYW

Southampton Eastleigh

Wed 21/10

09:15-17:15

2 stops37h 00m

Key West

Wed 28/10

07:40-08:10

2 stops20h 30m

£630

SouthamptonKey West

SOU Southampton Eastleigh - EYW Key West

SOUEYW

Southampton Eastleigh

Sat 16/1

09:20-11:36

2 stops31h 16m

Key West

Tue 19/1

19:33-11:55

2 stops35h 22m

£961

Flights are sorted by cheapest return flights first.

Deals found on 6/9

Sorted by cheapest first

Best time to book a flight from Southampton to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Southampton with our price prediction graph.
Estimated return price

Related info for your journey

  • How long is the flight from Southampton to Key West?

    For as low as £961, KLM can have you in Key West from Southampton in 31h 16m. The distance between Southampton and Key West is about 4507 mi. Both multi-stop and direct flights can be found to your destination and back.

  • Can I find deals for flights from Southampton to Key West that include hotel bookings?

    Yes. In addition to deals on Southampton to Key West flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Southampton to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Key West.

  • Can I find deals for business class flights from Southampton to Key West?

    Yes. Cheapflights offers flight deals from Southampton to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Certainly. Search results for flights to Key West from Southampton shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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