Find flights
Deals
When to book
FAQs

Cheap flights from Comayagua to Panama City from £245

XPL — PTY
11 Oct — 18 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Comayagua to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Comayagua to Panama City

Tue 22/911:35 -
Nonstop2h 06m
Tue 6/1022:33 -
Nonstop2h 00m
Deal found 9/9£245
Mon 12/1004:48 -
Nonstop2h 06m
Wed 4/1111:48 -
Nonstop1h 59m
Deal found 8/9£252
Sat 19/913:51 -
Nonstop2h 06m
Wed 23/909:40 -
Nonstop2h 00m
Deal found 10/9£253
Wed 14/1013:51 -
Nonstop2h 06m
Sun 18/1022:33 -
Nonstop2h 00m
Deal found 10/9£262
Thu 17/904:48 -
Nonstop2h 06m
Sat 26/922:33 -
Nonstop2h 00m
Deal found 8/9£270
Wed 11/1113:56 -
Nonstop2h 09m
Fri 20/1122:33 -
Nonstop1h 59m
Deal found 10/9£279
Sun 8/1119:40 -
1 stop5h 30m
Mon 18/105:30 -
1 stop14h 15m
Deal found 8/9£282
Fri 30/1005:03 -
Nonstop2h 06m
Mon 2/1111:48 -
Nonstop1h 59m
Deal found 10/9£287
Tue 17/1113:56 -
Nonstop2h 09m
Sun 22/1122:33 -
Nonstop1h 59m
Deal found 10/9£296
Mon 23/1113:56 -
Nonstop2h 09m
Mon 30/1111:48 -
Nonstop1h 59m
Deal found 9/9£304
Mon 26/1013:59 -
Nonstop2h 06m
Sun 1/1122:33 -
Nonstop1h 59m
Deal found 10/9£308
Mon 14/913:51 -
Nonstop2h 06m
Wed 16/922:33 -
Nonstop2h 00m
Deal found 10/9£313

Find flight deals from Comayagua to Panama City

Round-trip from

£245

Popular in

August

Cheapest in

January

Average price

£272
Copa Airlines
  • Copa Airlines
  • 22/9-20/10
  • Nonstop
  • 4h 06m total
  • Comayagua to Panama City
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (£9 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (£2 potential savings vs. average return price).
Search Deals
Average for round-trip flights in September 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Comayagua to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Sat 17/10

04:48-07:54

Nonstop2h 06m

Panama City Tocumen Intl

Thu 22/10

11:48-12:48

Nonstop2h 00m

£245

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Fri 25/9

11:35-14:41

Nonstop2h 06m

Panama City Tocumen Intl

Wed 30/9

09:40-10:40

Nonstop2h 00m

£245

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Mon 21/9

13:51-16:57

Nonstop2h 06m

Panama City Tocumen Intl

Wed 23/9

09:40-10:40

Nonstop2h 00m

£245

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Mon 12/10

04:48-07:54

Nonstop2h 06m

Panama City Tocumen Intl

Fri 16/10

22:33-23:33

Nonstop2h 00m

£245

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Sat 26/9

13:51-16:57

Nonstop2h 06m

Panama City Tocumen Intl

Wed 30/9

11:48-12:48

Nonstop2h 00m

£253
Fastest return journey

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Tue 20/10

11:35-14:41

Nonstop2h 06m

Panama City Tocumen Intl

Wed 31/12

00:00-23:00

Nonstop0h 00m

£265

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Tue 12/1

13:59-17:05

Nonstop2h 06m

Panama City Tocumen Intl

Wed 31/12

00:00-23:00

Nonstop0h 00m

£265

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Fri 18/9

11:35-14:41

Nonstop2h 06m

Panama City Tocumen Intl

Wed 31/12

00:00-23:00

Nonstop0h 00m

£265

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Tue 15/9

11:35-14:41

Nonstop2h 06m

Panama City Tocumen Intl

Wed 31/12

00:00-23:00

Nonstop0h 00m

£265

ComayaguaPanama City

XPL Comayagua Palmerola Intl - PTY Panama City Tocumen Intl

XPLPTY

Comayagua Palmerola Intl

Mon 21/9

04:48-07:54

Nonstop2h 06m

Panama City Tocumen Intl

Wed 31/12

00:00-23:00

Nonstop0h 00m

£265

Flights are sorted by cheapest return flights first.

Deals found on 9/9

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Comayagua to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Comayagua with our price prediction graph.
Estimated return price

Cheapflights Insights

Everything you need to know about your flight from Comayagua to Panama City

How far ahead should I book a flight from Comayagua to Panama City?

The best time to book flights from Comayagua to Panama City is 88 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Comayagua to Panama City?

Currently, January is the cheapest month in which you can book a flight from Comayagua to Panama City (average of £231). Flying from Comayagua to Panama City in August is currently the most expensive (average of £273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from XPL to PTY?

When flying from Comayagua to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost for a return flight from Comayagua to Panama City?

Airfare is typical for this route at the moment.

Comayagua to Panama City flights typically cost between £245 and £306 in September.
The cheapest return price found within the last 5 days was £245 on Copa Airlines (22 Sept–20 Oct).

Related info for your journey

  • How popular is this Comayagua to Panama City flight route?

    This flight path from Comayagua Palmerola Intl to Panama City Tocumen Intl was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Comayagua to Panama City?

    Copa Airlines can get you from Comayagua to Panama City in just under 2h 06m. Your travel time will be generally consistent. Airlines will cover a distance of 667 mi. Generally, flights for this route are direct.

  • What are the most reliable airlines from Comayagua to Panama City?

    The top 3 most reliable airlines when flying from Comayagua to Panama City are Iberia (94%), Copa Airlines (91%) and KLM (90%).

  • Can I find deals for flights from Comayagua to Panama City that include hotel bookings?

    Yes. In addition to deals on Comayagua to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Comayagua to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Comayagua to Panama City.

  • Can I find deals for business class flights from Comayagua to Panama City?

    Yes. Cheapflights offers flight deals from Comayagua to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Comayagua to Panama City?

    Currently, January is the cheapest month in which you can book a flight from Comayagua to Panama City (average of £231). Flying from Comayagua to Panama City in August is currently the most expensive (average of £273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Browse thousands of different options on Cheapflights for your next trip

Fly with Cheapflights

How does Cheapflights help users find flights from Comayagua to Panama City?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Panama City from Comayagua today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Comayagua to Panama City?

Millions of users choose and trust Cheapflights to book the best flight deals from Comayagua to Panama City for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Comayagua to Panama City with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Comayagua to Panama City, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Comayagua to Panama City become cheaper?

Yes, Cheapflights offers price alerts on Comayagua to Panama City flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.