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Cheap flights from Brussels Bruxelles-National Airport to Panama City from £459

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — PTY
18 Oct — 25 Oct1
1 adult
1 adult, Economy

Cheap flight deals from Bruxelles-National to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Bruxelles-National (BRU) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 September 2025.

Round-trip from

£457

Popular in

December

Cheapest in

May

Average price

£526
United Airlines
  • United Airlines
  • 9/2-6/3
  • 4 total stops
  • 62h 45m total
  • Brussels to Panama City
Search Deals
Highest demand for flights based on searches. 10% potential increase in price (£47 potential increase over avg. return price).
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Cheapest flight prices on average. 5% potential price decrease (£20 potential savings vs. average return price).
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Average for round-trip flights in September 2025
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Find flight deals from Bruxelles-National to Panama City

Cheapest flights from Bruxelles-National to Panama City
Explore the most affordable flight options available from Bruxelles-National to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 September 2025.

Sun 2/1111:55BRU - PTY
2 stops32h 00mUnited Airlines
Mon 17/1110:00PTY - BRU
1 stop16h 05mUnited Airlines
Deal found 16/9£459
Sun 2/1111:55BRU - PTY
2 stops32h 00mUnited Airlines
Wed 19/1110:00PTY - BRU
2 stops21h 15mUnited Airlines
Deal found 16/9£461
Wed 5/1111:55BRU - PTY
2 stops32h 00mUnited Airlines
Mon 24/1110:00PTY - BRU
1 stop16h 05mUnited Airlines
Deal found 17/9£462
Thu 16/1012:00BRU - PTY
2 stops32h 50mUnited Airlines
Thu 23/1009:45PTY - BRU
1 stop15h 00mUnited Airlines
Deal found 18/9£462
Sun 2/1111:55BRU - PTY
2 stops32h 00mUnited Airlines
Sun 16/1110:00PTY - BRU
2 stops21h 15mUnited Airlines
Deal found 17/9£463
Thu 9/1011:15BRU - PTY
1 stop33h 35mUnited Airlines
Wed 22/1009:45PTY - BRU
2 stops20h 30mUnited Airlines
Deal found 18/9£464
Sun 2/1111:55BRU - PTY
2 stops32h 00mUnited Airlines
Sun 9/1110:00PTY - BRU
2 stops18h 20mUnited Airlines
Deal found 18/9£466
Wed 5/1111:55BRU - PTY
2 stops32h 00mUnited Airlines
Sun 23/1110:00PTY - BRU
2 stops18h 10mUnited Airlines
Deal found 17/9£467
Wed 5/1118:55BRU - PTY
1 stop30h 50mAir Europa
Sat 29/1121:30PTY - BRU
1 stop14h 15mAir Europa
Deal found 17/9£487
Mon 3/1111:55BRU - PTY
2 stops32h 00mUnited Airlines
Sat 15/1110:00PTY - BRU
1 stop16h 05mUnited Airlines
Deal found 16/9£494
Tue 11/1111:55BRU - PTY
2 stops32h 00mUnited Airlines
Mon 19/110:00PTY - BRU
1 stop16h 05mUnited Airlines
Deal found 16/9£498

Cheapflights Fare Finder

 
Customise your flight search to find flights from Bruxelles-National to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 September 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Panama City that are best for you.

Fly from

Bruxelles-National

Fly to

Panama City

Route

Depart

Return

Price

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Thu 8/1

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Thu 5/2

16:41-08:05

2 stops33h 24m

£459

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Sun 2/11

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Thu 13/11

10:00-08:05

1 stop16h 05m

£459

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Sun 2/11

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Tue 18/11

10:00-13:15

2 stops21h 15m

£461

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Thu 4/12

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Mon 29/12

23:55-13:15

2 stops31h 20m

£461

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Tue 4/11

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Sun 16/11

10:00-13:15

2 stops21h 15m

£461

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Mon 3/11

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Thu 13/11

08:55-13:15

2 stops22h 20m

£461

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Tue 4/11

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Tue 18/11

08:55-13:15

2 stops22h 20m

£461

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Mon 3/11

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Mon 17/11

10:00-08:05

1 stop16h 05m

£462

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Mon 3/11

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Wed 19/11

10:00-08:05

1 stop16h 05m

£462

BrusselsPanama City

BRU - PTY

BRUPTY

Brussels Bruxelles-National

Mon 9/2

11:55-13:55

2 stops32h 00m

Panama City Tocumen Intl

Mon 9/3

22:55-07:50

2 stops26h 55m

£462

Flights are sorted by cheapest return flights first.

Deals found on 16/9

Showing 1-10 of 11 results
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2

Best time to book a flight from Bruxelles-National to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Bruxelles-National with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Brussels Bruxelles-National Airport to Panama City

How far ahead should I book a flight from Brussels Bruxelles-National Airport to Panama City?

Use this chart to determine the optimal time to book a return flight from Bruxelles-National to Panama City. Price data was last updated on 12 September 2025.

The best time to book flights from Brussels Bruxelles-National Airport to Panama City is 32 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Panama City?

Currently, April is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Panama City (average of £763). Flying from Brussels Bruxelles-National Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost for a return flight from Brussels Bruxelles-National Airport to Panama City?

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Brussels Bruxelles-National?

    If you book a flight to Panama City from Brussels Bruxelles-National, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Brussels Bruxelles-National to Tocumen Intl per day from 0 different airlines.

  • How long is the flight from Brussels Bruxelles-National Airport to Panama City?

    Departing from Brussels Bruxelles-National Airport to Panama City will take you 32h. The distance from Brussels Bruxelles-National Airport to Panama City is about 5462 mi.

  • Can I find deals for flights from Bruxelles-National to Panama City that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Panama City.

  • Can I find deals for business class flights from Bruxelles-National to Panama City?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Panama City (average of £763). Flying from Brussels Bruxelles-National Airport to Panama City in December is currently the most expensive (average of £1,051). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Can Cheapflights find flights from Bruxelles-National to Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Bruxelles-National to Panama City flexibly with Cheapflights today.

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Yes! Start tracking prices for Bruxelles-National to Panama City flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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