Find a great deal and save up to 8% by booking at least 46 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Southampton to St. Louis within the next two weeks, with the cheapest ticket starting at £700.
Due to multiple factors, expect to potentially pay more when booking in July. For low rates, January can be a great choice for travel to St. Louis. Flights to St. Louis from Southampton in January are about £672 on average during January, but can be found for as low as £509.
When flying from Southampton to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.