How long is the flight from Southampton to Panama City?

Airlines like KLM fly from Southampton to Panama City in about 29h 30m. The time it takes to get you to your destination can typically vary by up to . The distance between Southampton and Panama City is about 5208 mi.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 inches per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

What is the cheapest time of day to fly from SOU to PTY?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Southampton to Panama City as you normally would.

Can I find deals for flights from Southampton to Panama City that include hotel bookings?

Yes. In addition to deals on Southampton to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.

How can I find direct flights from Southampton to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Panama City.

Can I find deals for business class flights from Southampton to Panama City?

Yes. Cheapflights offers flight deals from Southampton to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

£533+ Cheap Flights from Southampton to Panama City

Cheap flight deals from Southampton to Panama City

Enter your travel dates to find the best prices.

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Best

Last-minute

One-way

Cheapest flights from Southampton to Panama City
Explore the most affordable flight options available from Southampton to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 September 2026.

Mon 19/1017:20 -

1 stop29h 30m

Mon 26/1022:30 -

2 stops37h 35m

Deal found 4/9£740

Sat 17/1017:20 -

1 stop29h 30m

Sat 24/1011:25 -

2 stops39h 45m

Deal found 2/9£777

Sat 17/1017:20 -

1 stop29h 30m

Sat 24/1018:50 -

1 stop32h 20m

Deal found 2/9£867

Sun 4/1017:20 -

1 stop29h 30m

Sun 11/1018:50 -

1 stop31h 45m

Deal found 4/9£880

Sun 4/1020:00 -

2 stops28h 40m

Sun 11/1020:25 -

2 stops30h 15m

Deal found 4/9£935

Thu 31/1217:30 -

1 stop28h 00m

Sun 17/121:48 -

2 stops38h 12m

Deal found 6/9£956

Thu 31/1217:30 -

2 stops36h 50m

Sun 17/121:48 -

2 stops38h 12m

Deal found 6/9£983

Find flight deals from Southampton to Panama City

Round-trip from	£740
One-way from	£533
Popular in	December
Cheapest in	November
Average price	£666

KLM
19/10-26/10
3 total stops
67h 05m total
Southampton to Panama City

Search Deals

31/10-31/12
3 total stops
39h 25m total
Southampton to Panama City

Search Deals

Highest demand for flights based on searches. 3% potential increase in price (£17 potential increase over avg. return price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease (£12 potential savings vs. average return price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Southampton to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Sat 31/10

09:20-19:45

2 stops39h 25m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£571

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Sat 31/10

09:25-16:30

1 stop36h 05m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£726

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Mon 19/10

17:20-16:50

1 stop29h 30m

Panama City Tocumen Intl

Mon 26/10

22:30-17:05

2 stops37h 35m

£740

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Sat 17/10

17:20-16:50

1 stop29h 30m

Panama City Tocumen Intl

Sat 24/10

10:10-09:10

3 stops41h 00m

£819

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Sun 4/10

17:20-16:50

1 stop29h 30m

Panama City Tocumen Intl

Sun 11/10

18:50-08:35

1 stop31h 45m

£880

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Sat 12/9

17:20-12:58

2 stops49h 38m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£891

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Mon 14/9

09:05-12:58

2 stops57h 53m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£891

Fastest return journey

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Wed 16/9

09:15-12:58

2 stops33h 43m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£891

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Thu 17/9

17:20-12:58

2 stops49h 38m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£891

SouthamptonPanama City

SOU Southampton Eastleigh - PTY Panama City Tocumen Intl

SOUPTY

Southampton Eastleigh

Sun 13/9

09:15-12:58

2 stops33h 43m

Panama City Tocumen Intl

Wed 31/12

00:00-06:00

Nonstop0h 00m

£892

Flights are sorted by cheapest return flights first.

Deals found on 4/9

Showing 1-10 of 14 resultsSorted by cheapest first

Best time to book a flight from Southampton to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Southampton with our price prediction graph.

SOU-PTY

Estimated return price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Southampton to Panama City?
Airlines like KLM fly from Southampton to Panama City in about 29h 30m. The time it takes to get you to your destination can typically vary by up to . The distance between Southampton and Panama City is about 5208 mi.
Can I find deals for flights from Southampton to Panama City that include hotel bookings?
Yes. In addition to deals on Southampton to Panama City flights, Cheapflights offers holiday packages that include both flights and hotel.
How can I find direct flights from Southampton to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Southampton to Panama City.
Can I find deals for business class flights from Southampton to Panama City?
Yes. Cheapflights offers flight deals from Southampton to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Deals for Southampton to Panama City flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Southampton to Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights to Panama City from Southampton.

Can Cheapflights find flights from Southampton to Panama City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Southampton to Panama City flexibly with Cheapflights today.

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Yes! Start tracking prices for Southampton to Panama City flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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Cheap flights from Southampton to Panama City from £533

This is the cheapest retur flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/10. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Southampton to Panama City

Cheapest flights from Southampton to Panama CityExplore the most affordable flight options available from Southampton to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 September 2026.

Explore the most affordable flight options available from Southampton to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 September 2026.

Best flights from Southampton to Panama CityDiscover carefully curated flight deals from Southampton to Panama City that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 September 2026.

Discover carefully curated flight deals from Southampton to Panama City that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 September 2026.

Last-minute flights from Southampton to Panama CityDiscover last-minute flight deals from Southampton to Panama City. Data last updated 6 September 2026 and is based on user searches.

Discover last-minute flight deals from Southampton to Panama City. Data last updated 6 September 2026 and is based on user searches.

One-way flights from Southampton to Panama CitySearch for one-way flight options from Southampton to Panama City. Find affordable one-way fares based on user searches. Data last updated 6 September 2026.

Search for one-way flight options from Southampton to Panama City. Find affordable one-way fares based on user searches. Data last updated 6 September 2026.

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Best time to book a flight from Southampton to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Southampton with our price prediction graph.

Related info for your journey

How long is the flight from Southampton to Panama City?

Can I find deals for flights from Southampton to Panama City that include hotel bookings?

How can I find direct flights from Southampton to Panama City?

Can I find deals for business class flights from Southampton to Panama City?

Travelling to a place near Panama City?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Southampton to Panama City

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Complete your trip

Complete your trip to Panama City by adding a car hire and/or hotel booking to your travel itinerary.

Search flights from Southampton to Panama City by cabin class

Find flights from Southampton to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Southampton and Panama City flights

Browse other Southampton and Panama City flight options. Last updated on 6 September 2026.

Other flights from Southampton

Browse through other flights departing from Southampton. Flights are based on user searches made on Cheapflights and were last updated on 6 September 2026.

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Can Cheapflights notify me if prices for flights from Southampton to Panama City become cheaper?

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Cheapest flights from Southampton to Panama City
Explore the most affordable flight options available from Southampton to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 6 September 2026.

Best flights from Southampton to Panama City
Discover carefully curated flight deals from Southampton to Panama City that have cost, travel time, and stopovers in mind to ensure you get the best travel experience. Data last updated 6 September 2026.

Last-minute flights from Southampton to Panama City
Discover last-minute flight deals from Southampton to Panama City. Data last updated 6 September 2026 and is based on user searches.

One-way flights from Southampton to Panama City
Search for one-way flight options from Southampton to Panama City. Find affordable one-way fares based on user searches. Data last updated 6 September 2026.