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Cheap flights from San Diego to Southampton from £509

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 20/6. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SOU
17 Apr — 24 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from San Diego to Southampton

Enter your travel dates to find the best prices.

Cheapest flights from San Diego to Southampton
Explore the most affordable flight options available from San Diego to Southampton. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 March 2026.

Mon 28/907:00
SAN
-
SOU
2 stops17h 35m
KLM
Tue 13/1009:05
SOU
-
SAN
2 stops22h 40m
KLM
Deal found 16/3£710
Wed 29/406:25
SAN
-
SOU
2 stops18h 10m
KLM
Wed 6/509:05
SOU
-
SAN
1 stop34h 45m
KLM
Deal found 14/3£749
Tue 26/513:40
SAN
-
SOU
1 stop34h 55m
KLM
Mon 8/617:20
SOU
-
SAN
1 stop26h 30m
KLM
Deal found 15/3£840
Tue 26/510:59
SAN
-
SOU
2 stops21h 51m
Delta
Mon 8/617:20
SOU
-
SAN
1 stop26h 30m
Delta
Deal found 15/3£844
Wed 1/406:15
SAN
-
SOU
2 stops18h 20m
KLM
Sun 5/409:15
SOU
-
SAN
2 stops19h 30m
KLM
Deal found 16/3£921
Tue 26/507:00
SAN
-
SOU
3 stops28h 30m
Multiple Airlines
Mon 8/618:20
SOU
-
SAN
2 stops29h 05m
Multiple Airlines
Deal found 15/3£1,139
Wed 1/417:15
SAN
-
SOU
2 stops19h 30m
Multiple Airlines
Sun 5/409:20
SOU
-
SAN
3 stops34h 40m
Multiple Airlines
Deal found 16/3£1,998

Find flight deals from San Diego to Southampton

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Southampton (SOU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 18 March 2026.

Round-trip from

£749

One-way from

£509

Popular in

June

Cheapest in

October

Average price

£570
KLM
  • KLM
  • 29/4-6/5
  • 3 total stops
  • 52h 55m total
  • San Diego to Southampton
Search Deals
Delta
  • Delta
  • 20/6
  • 2 total stops
  • 19h 15m total
  • San Diego to Southampton
Search Deals
Highest demand for flights based on searches. 25% potential increase in price (£159 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£26 potential savings vs. average return price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from San Diego to Southampton that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 18 March 2026.
Use the filters below to find and compare flights from San Diego to Southampton that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Wed 29/4

06:25-08:35

2 stops18h 10m

Southampton Eastleigh

Wed 6/5

09:05-11:50

1 stop34h 45m

£749

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Tue 26/5

10:59-16:50

2 stops21h 51m

Southampton Eastleigh

Mon 8/6

09:05-22:48

2 stops21h 43m

£896
Fastest return journey

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Wed 1/4

06:15-08:35

2 stops18h 20m

Southampton Eastleigh

Sun 5/4

09:15-20:45

2 stops19h 30m

£921

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Wed 1/4

17:15-20:45

2 stops19h 30m

Southampton Eastleigh

Sun 5/4

09:20-12:00

3 stops34h 40m

£1,998

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Sun 23/8

16:45-08:25

2 stops31h 40m

Southampton Eastleigh

Thu 27/8

18:20-17:50

2 stops31h 30m

£4,194
Cheapest one-way
Fastest single journey

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Sat 20/6

13:40-08:35

1 stop34h 55m

£645

Flights are sorted by cheapest return flights first.

Deals found on 16/3

Sorted by cheapest first

Best time to book a flight from San Diego to Southampton

Have a flexible travel schedule? Discover the best time to fly to Southampton from San Diego with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Southampton

What is the cheapest month to book a flight from San Diego to Southampton?

Currently, December is the cheapest month in which you can book a flight from San Diego to Southampton (average of £352). Flying from San Diego to Southampton in June is currently the most expensive (average of £702). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Southampton. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Diego to Southampton?

    KLM and Delta can get you from San Diego to Southampton in just under 18h 10m. Your travel time can differ by up to 3h 41m. San Diego and Southampton are separated by a distance of 5462 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from San Diego to Southampton that include hotel bookings?

    Yes. In addition to deals on San Diego to Southampton flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Southampton?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Southampton.

  • Can I find deals for business class flights from San Diego to Southampton?

    Yes. Cheapflights offers flight deals from San Diego to Southampton by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Southampton?

    Currently, December is the cheapest month in which you can book a flight from San Diego to Southampton (average of £352). Flying from San Diego to Southampton in June is currently the most expensive (average of £702). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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How does Cheapflights help users find flights from San Diego to Southampton?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Southampton from San Diego today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from San Diego to Southampton?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from San Diego to Southampton.

Can Cheapflights find flights from San Diego to Southampton with no change fees?

Yes, we can. To see specific flights from San Diego to Southampton with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from San Diego to Southampton become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Southampton from San Diego today and book when prices fit your budget.

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