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Cheap flights from San Diego to Southampton from £357

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/7. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SOU
3 Mar — 10 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from San Diego to Southampton

Enter your travel dates to find the best prices.

Cheapest flights from San Diego to Southampton
Explore the most affordable flight options available from San Diego to Southampton. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 1 February 2026.

Tue 28/713:40
SAN
-
SOU
1 stop19h 55m
Delta
Wed 12/818:05
SOU
-
SAN
1 stop25h 45m
Delta
Deal found 30/1£637
Sun 26/706:15
SAN
-
SOU
2 stops27h 20m
Delta
Wed 12/818:05
SOU
-
SAN
1 stop25h 45m
Delta
Deal found 30/1£640
Thu 30/707:00
SAN
-
SOU
2 stops17h 45m
Delta
Wed 12/818:05
SOU
-
SAN
1 stop25h 45m
Delta
Deal found 30/1£676
Tue 28/713:40
SAN
-
SOU
1 stop19h 55m
Delta
Sat 15/809:15
SOU
-
SAN
2 stops18h 43m
Delta
Deal found 30/1£687
Sun 26/706:20
SAN
-
SOU
2 stops18h 25m
Delta
Sat 15/809:15
SOU
-
SAN
2 stops18h 43m
Delta
Deal found 30/1£691
Wed 19/813:35
SAN
-
SOU
2 stops35h 10m
Air Europa
Mon 31/817:20
SOU
-
SAN
1 stop26h 30m
Air Europa
Deal found 31/1£697
Sun 3/506:15
SAN
-
SOU
2 stops18h 20m
Scandinavian Airlines
Sat 9/517:20
SOU
-
SAN
2 stops34h 53m
Scandinavian Airlines
Deal found 28/1£721
Thu 30/707:00
SAN
-
SOU
2 stops17h 45m
Delta
Sat 15/809:15
SOU
-
SAN
2 stops34h 47m
Delta
Deal found 30/1£735
Wed 19/806:20
SAN
-
SOU
2 stops18h 25m
Multiple Airlines
Mon 31/809:05
SOU
-
SAN
2 stops17h 49m
Multiple Airlines
Deal found 31/1£761
Sun 26/706:20
SAN
-
SOU
2 stops18h 25m
Delta
Sun 9/809:15
SOU
-
SAN
2 stops22h 04m
Delta
Deal found 30/1£881
Thu 30/713:40
SAN
-
SOU
1 stop19h 55m
Delta
Fri 14/809:15
SOU
-
SAN
1 stop34h 35m
Delta
Deal found 30/1£907

Find flight deals from San Diego to Southampton

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Southampton (SOU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 1 February 2026.

Round-trip from

£637

One-way from

£357

Popular in

June

Cheapest in

October

Average price

£515
Delta
  • Delta
  • 28/7-12/8
  • 2 total stops
  • 45h 40m total
  • San Diego to Southampton
Search Deals
Delta
  • Delta
  • 28/7
  • 1 total stop
  • 19h 55m total
  • San Diego to Southampton
Search Deals
Highest demand for flights based on searches. 25% potential increase in price (£154 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (£25 potential savings vs. average return price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from San Diego to Southampton that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 1 February 2026.
Use the filters below to find and compare flights from San Diego to Southampton that are best for you.

Fly from

San Diego

Fly to

Southampton

Route

Depart

Return

Price

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Tue 28/7

07:00-17:35

2 stops26h 35m

Southampton Eastleigh

Wed 12/8

18:05-11:50

1 stop25h 45m

£640

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Mon 27/7

22:10-17:35

2 stops35h 25m

Southampton Eastleigh

Wed 12/8

18:05-11:50

1 stop25h 45m

£640

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Sun 26/7

06:15-17:35

2 stops27h 20m

Southampton Eastleigh

Wed 12/8

18:05-11:50

1 stop25h 45m

£640

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Thu 30/7

07:00-08:45

2 stops17h 45m

Southampton Eastleigh

Wed 12/8

18:05-11:50

1 stop25h 45m

£676

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Tue 28/7

13:40-17:35

1 stop19h 55m

Southampton Eastleigh

Sat 15/8

09:15-19:58

2 stops18h 43m

£687

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Sun 26/7

06:20-08:45

2 stops18h 25m

Southampton Eastleigh

Sat 15/8

09:15-19:58

2 stops18h 43m

£691

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Mon 27/7

22:10-08:45

2 stops26h 35m

Southampton Eastleigh

Sat 15/8

09:15-19:58

2 stops18h 43m

£691

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Sun 3/5

06:15-08:35

2 stops18h 20m

Southampton Eastleigh

Sat 9/5

17:20-20:13

2 stops34h 53m

£721

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Tue 28/7

14:00-17:35

2 stops19h 35m

Southampton Eastleigh

Sun 9/8

09:15-21:44

2 stops20h 29m

£881

San DiegoSouthampton

SAN - SOU

SANSOU

San Diego

Tue 28/7

13:40-17:35

1 stop19h 55m

£357

Flights are sorted by cheapest return flights first.

Deals found on 30/1

Showing 1-10 of 14 results
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Best time to book a flight from San Diego to Southampton

Have a flexible travel schedule? Discover the best time to fly to Southampton from San Diego with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Southampton

What is the cheapest month to book a flight from San Diego to Southampton?

Currently, December is the cheapest month in which you can book a flight from San Diego to Southampton (average of £342). Flying from San Diego to Southampton in June is currently the most expensive (average of £665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Southampton. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Diego to Southampton?

    Delta can get you from San Diego to Southampton in just under 26h 35m. Your travel time can differ by up to . San Diego and Southampton are separated by a distance of 5462 mi.

  • Can I find deals for flights from San Diego to Southampton that include hotel bookings?

    Yes. In addition to deals on San Diego to Southampton flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Southampton?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Southampton.

  • Can I find deals for business class flights from San Diego to Southampton?

    Yes. Cheapflights offers flight deals from San Diego to Southampton by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Southampton?

    Currently, December is the cheapest month in which you can book a flight from San Diego to Southampton (average of £342). Flying from San Diego to Southampton in June is currently the most expensive (average of £665). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Diego to Southampton

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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from San Diego to Southampton?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Southampton from San Diego today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from San Diego to Southampton?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from San Diego to Southampton.

Can Cheapflights find flights from San Diego to Southampton with no change fees?

Yes, we can. To see specific flights from San Diego to Southampton with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from San Diego to Southampton become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Southampton from San Diego today and book when prices fit your budget.

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