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Cheap flights from Prague to Southampton from £110

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 24/5. Fares are subject to change and may not be available on all flights or dates of travel.
PRG — SOU
30 May — 6 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Prague to Southampton

Enter your travel dates to find the best prices.

Cheapest flights from Prague to Southampton
Explore the most affordable flight options available from Prague to Southampton. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 April 2026.

Tue 12/506:20
PRG
-
SOU
1 stop14h 10m
Multiple Airlines
Sat 16/512:15
SOU
-
PRG
2 stops21h 10m
Multiple Airlines
Deal found 26/4£175
Sat 25/709:50
PRG
-
SOU
1 stop27h 15m
Multiple Airlines
Sat 8/818:50
SOU
-
PRG
1 stop13h 50m
Multiple Airlines
Deal found 29/4£213
Mon 11/518:35
PRG
-
SOU
2 stops25h 55m
Multiple Airlines
Sun 24/509:20
SOU
-
PRG
2 stops26h 15m
Multiple Airlines
Deal found 27/4£234
Mon 11/508:50
PRG
-
SOU
1 stop24h 45m
KLM
Sun 24/509:15
SOU
-
PRG
1 stop22h 05m
KLM
Deal found 27/4£343
Wed 29/420:30
PRG
-
SOU
1 stop13h 05m
KLM
Sat 9/517:20
SOU
-
PRG
1 stop4h 15m
KLM
Deal found 25/4£350

Find flight deals from Prague to Southampton

Discover tips and strategies to find the most affordable flight options for your journey from Prague (PRG) to Southampton (SOU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 April 2026.

Round-trip from

£175

One-way from

£110

Popular in

April

Cheapest in

January

Average price

£116
12/5-16/5
  • 12/5-16/5
  • 3 total stops
  • 35h 20m total
  • Prague to Southampton
Search Deals
24/5
  • 24/5
  • 2 total stops
  • 41h 55m total
  • Prague to Southampton
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (£6 potential increase over avg. return price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (£2 potential savings vs. average return price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customise your flight search to find flights from Prague to Southampton that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 858,174 searches. Data last updated 30 April 2026.
Use the filters below to find and compare flights from Prague to Southampton that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest return flight

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Tue 12/5

07:10-08:05

2 stops25h 55m

Southampton Eastleigh

Sat 16/5

12:15-10:25

2 stops21h 10m

£176

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Mon 11/5

18:35-19:30

2 stops25h 55m

Southampton Eastleigh

Sun 24/5

09:20-12:35

2 stops26h 15m

£234

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Sat 25/7

13:55-12:05

2 stops23h 10m

Southampton Eastleigh

Sat 8/8

07:50-08:50

2 stops24h 00m

£276

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Mon 11/5

08:50-08:35

1 stop24h 45m

Southampton Eastleigh

Sun 24/5

09:15-08:20

1 stop22h 05m

£343
Fastest return journey

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Fri 4/9

07:05-19:25

2 stops13h 20m

Southampton Eastleigh

Sat 5/9

10:15-09:45

2 stops22h 30m

£487

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Tue 12/5

17:10-12:55

2 stops20h 45m

Southampton Eastleigh

Sat 16/5

19:40-23:10

2 stops26h 30m

£547

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Fri 15/5

07:05-08:25

2 stops26h 20m

Southampton Eastleigh

Mon 18/5

12:20-23:15

2 stops9h 55m

£631

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Fri 15/5

07:05-12:05

2 stops30h 00m

Southampton Eastleigh

Tue 19/5

15:15-23:25

2 stops31h 10m

£664
Cheapest one-way

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Sun 24/5

15:45-08:40

2 stops41h 55m

£110

PragueSouthampton

PRG - SOU

PRGSOU

Václav Havel Prague

Fri 7/8

17:50-09:45

2 stops16h 55m

£244

Flights are sorted by cheapest return flights first.

Deals found on 29/4

Showing 1-10 of 17 resultsSorted by cheapest first
1
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Best time to book a flight from Prague to Southampton

Have a flexible travel schedule? Discover the best time to fly to Southampton from Prague with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Prague to Southampton. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Prague to Southampton?

    Departing from Prague to Southampton will take you 24h 45m. There are 687 mi between Prague and Southampton.

  • Can I find deals for flights from Prague to Southampton that include hotel bookings?

    Yes. In addition to deals on Prague to Southampton flights, Cheapflights offers holiday packages that include both flights and hotel.

  • How can I find direct flights from Prague to Southampton?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Prague to Southampton.

  • Can I find deals for business class flights from Prague to Southampton?

    Yes. Cheapflights offers flight deals from Prague to Southampton by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Why should you use Cheapflights to find cheap flight tickets from Prague to Southampton?

Cheapflights simply makes it quick and affordable to book flights from Prague to Southampton by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Prague to Southampton with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Prague to Southampton flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Prague to Southampton become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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